
How Biomarkers Are Shaping the Future of Skin Disease Treatment
04 February 2025
Discover how biomarkers are revolutionizing the treatment of skin diseases by enabling more precise and effective therapies.

Breaking Barriers in Women’s Health: The World’s First Live Birth Using Fertilo
21 January 2025
Discover how Gameto achieved the world’s first live birth using Fertilo, a revolutionary in vitro oocyte maturation technology. Learn about its stem cell-driven innovation and how it's transforming fertility care for women worldwide.

Redefining Success in IBD Drug Discovery with Human Tissue Models
11 December 2024
Redefining IBD drug discovery with a dual-pronged approach through human bioengineered and fresh tissue.

Pharma AI is Changing Clinical Trials by Optimizing Patient Selection
27 November 2024
AI is revolutionizing clinical trials by optimizing patient selection, improving trial outcomes, and accelerating the development of new drugs.

Key Strategies Central Labs Use to Fast-Track Time to Market
18 November 2024
Learn how central labs use automation, outsourcing, and AI to accelerate drug development, reduce costs, and improve clinical trial accuracy and efficiency.

REPROCELL's Advanced Skin Tissue Engineering
31 October 2024
Discover REPROCELL's pioneering 3D skin tissue engineering, enhancing drug development and skincare research with accurate and robust human skin models.

Plasma or Serum? – You Decide.
17 October 2024
Discover the key differences between plasma and serum, their collection methods, and their impact on clinical and experimental outcomes.

From Fibroblasts to Cancer-Attacking Cells: Insights from Recent Research on Natural Killer Cells Derived from Clinical Grade iPSCs
16 October 2024
Discover the differentiation potential of induced pluripotent stem cells (iPSC) to cytotoxic NK cells, including recent advancements in research and therapy.

The Power of Human Tissue Models in Preclinical Research
03 October 2024
Discover how human tissue models are transforming drug safety assessments and improving outcomes in preclinical research through real-world case studies.

What you should know about the FDA’s Biological License Application Process
19 September 2024
Learn about the FDA's Biological License Application process, including submission requirements, review phases, and expedited pathways for biologics approvals.

High Prevalence of BRCA Mutations in Indian Breast Cancer Patients: Insights from a Diagnostic Lab
09 September 2024
High prevalence of BRCA mutations in Indian breast cancer patients underscores the need for tailored genetic testing and early detection strategies.

Understanding Safety Pharmacology in Human Tissues
26 August 2024
Explore the role of safety pharmacology in drug discovery, and the importance of human tissue studies for predicting and mitigating potential effects.

Breaking Ground in Alzheimer’s Research: A New Path to Drug Discovery and Personalized Medicine
22 August 2024
Breaking new ground in Alzheimer's research, a study by Durham University uncovers potential therapeutic targets using advanced stem cell technology.

Nucleic Acid Extraction in Clinical Research
08 August 2024
REPROCELL is revolutionizing drug discovery in clinical research through nucleic acid extraction.

Embracing Every Pathway with #NoWrongPath
06 August 2024
This year, we took part in the social media movement #NoWrongPath. Discover our colleagues inspiring story about how he got to where he is today!

Need To Conduct a Multi-Variable Study? REPROCELL Can Help with That!
18 July 2024
Conducting a multi-variable study on cancer risk and family history? Discover how our biorepository and custom collections can assist in your research.

AI in Drug Discovery: The Role of SHAP in Pharmacology
11 July 2024
Learn how Explainable AI, like SHAP, is transforming drug discovery by providing transparency and clarity in machine learning models.

Custom Oligosynthesis: Tailoring Solutions for Specific Research Needs
27 June 2024
Custom oligosynthesis offers tailored solutions for specific research needs, enhancing genetic research, diagnostics, and therapeutics.

Engineered Pigmented Skin Equivalents Reveal UV Protection Mechanisms
18 June 2024
Discover how engineered pigmented skin equivalents reveal UV protection mechanisms and offer insights into skin health at a molecular level.

Harnessing Functional Genomics to Revolutionize Inflammatory Bowel Disease Treatment
07 June 2024
Discover how functional genomics is transforming IBD treatment with groundbreaking research on ETS2's role in inflammation.

REPROCELL USA Inaugurates New GMP Laboratory
07 June 2024
May 15, 2024: REPROCELL USA inaugurated its new GMP BioManufacturing Lab. The facility enables hiPSC and hMSC generation in a contaminant-free environment.

Harnessing the Power of Mesenchymal Stem Cells
27 May 2024
Discover the groundbreaking potential of Mesenchymal Stem Cells (MSCs) in biomedical research and therapeutic development.

What to consider when selecting a central laboratory provider
07 May 2024
There are a lot of factors to take into consideration when choosing a central laboratory service. Let's walk through them together.

Leveraging Human Tissue Models with Preclinical and Drug Discovery CRO
05 April 2024
Our Preclinical and Drug Discovery CRO is transforming the landscape of drug development with new technologies and ethically sourced human tissue models.

ec23: A Promising ATRA Alternative for Advancing Stem Cell Research
13 December 2023
Learn how ec23 acts as a improved alternative to ATRA.

Quality Control: What is really in your hiPSC culture?
11 December 2023
Whatever the goals of your project, a robust QC testing protocol assessing sterility, pluripotency, and genetic abnormalities, while maintaining sample identity, is critical.

Exploring CHIR99021: The Key to Stem Cell Research and Beyond
20 November 2023
CHIR 99021 effects on Wnt/β-catenin pathway

Data Privacy and Protection in AI for Precision Medicine
31 October 2023
Discover how AI is revolutionizing data protection and security in precision medicine.

Bias in AI for precision medicine
02 October 2023
Without proper and due consideration in the design and delivery of new therapies and diagnostics, there is a risk that biased datasets will skew outcomes towards certain groups.

Outsourcing AI-assisted clinical trial analytics software: what to consider
29 August 2023
Outsourcing clinical trial analytics? Choose a vendor that prioritizes security, data quality, and model explainability.

Editing B2M and CIITA to Create Hypoimmune Cell Lines for Cell Therapy
29 August 2023
Gene editing is a viable approach for reducing immunogenicity of iPSC-derived therapeutic cells. The B2M and CIITA HLA-regulatory genes are good targets.

Clinical trial analytics using AI: everything you need to know
14 August 2023
Explore the power of clinical trial analytics in shaping healthcare. Learn about data insights, machine learning, bias, and ethical considerations

Why do patients respond differently to drugs? AI may provide an answer
05 May 2023
Learn how artificial intelligence combined with human tissue testing could help us understand why patients respond to drugs differently.

Wire myography: the ultimate guide (protocol included)
25 April 2023
Learn how to measure the reactivity and functional response of arteries in the wire myograph system in our wire myograph protocol.

Alternative testing methods covered by the FDA Modernization Act 2.0
06 March 2023
Discover whether the FDA Modernization Act 2.0. will increase the use of non-animal, alternative testing methods in drug development.

Everything you need to know about the motilin receptor
21 February 2023
Explore the function, physiology, & pharmacology of the motilin receptor. Discover what models can be used to investigate motilin mimetics preclinically.

Make a Difference with Fresh Residual Human Tissue Donation for Research – How to Get Involved!
31 January 2023
Discover the importance of fresh human tissue to healthcare development. Explore some of the options to donate residual tissue to pharmaceutical research.

Clinical Trials: An Evolutionary Perspective
18 January 2023
Find out how clinical trial systems and processes have developed and evolved during human history.

From rat aorta to resistance arteries: measuring vascular contractility
16 January 2023
Explore how isolated blood vessels can be used to determine drug behavior and discover translational alternatives to measuring vascular tone in rat aorta.

Recombinant Human Laminins and their Use in Cell Culture
05 January 2023
Discover the biological processes that laminin regulates. Learn more about the use of laminin in stem cell research and culture.

Everything we know about resistance arteries
21 November 2022
Learn about the physiology of resistance arteries in health and disease. Discover why they are important for controlling blood flow to vital organs.

4 ways ex vivo models offer Pharma better alternatives to animal testing
01 November 2022
Learn more about ex vivo models, and how these under-appreciated systems are helping Pharma reduce animal testing.

How to isolate PBMCs from whole blood using density gradient centrifugation
19 October 2022
Find out how to isolate PBMCs from whole blood samples using density gradient centrifugation a.k.a. the Ficoll Overlay method.

REPROCELL’s Stemgent Brings mRNA Reprogramming to the Clinical Sector
14 October 2022
Discover how REPROCELL has employed its StemRNA™ 4th Generation Reprogramming Technology to bring the power of mRNA reprogramming to the clinical sector.

Everything we know about the human relaxin peptide family
28 September 2022
Discover the physiology and pharmacology of the human relaxin peptide family and their analogs. Learn about the role of human tissue in ex vivo research.

Endogenous and exogenous affectors of uterine contractility
27 September 2022
Discover everything you need to know about ex vivo uterine contractility models. Learn about the use of uterine tissue in drug development and research.

How human fresh tissue models are helping RCD405 achieve regulatory approval
17 August 2022
Discover how Arcede Pharma recently used human tissue testing to generate preclinical efficacy data for their compound RCD405.

What are PBMCs? Everything you need to know about Peripheral Blood Mononuclear Cells
10 August 2022
PBMC is short for Peripheral Blood Mononuclear Cell, or any blood cell with a single nucleus. Many of our immune cells are PBMCs, including lymphocytes.

Protocol for buffy coat preparation from whole blood
09 August 2022
Read our simple, three-step protocol for buffy coat preparation from whole blood. Learn how you can isolate the buffy-coat from whole blood samples.

Protocol for PBMC isolation from buffy coat samples
09 August 2022
Learn how to isolate Peripheral Blood Mononuclear Cells (PBMCs) from buffy coat samples. Discover a protocol for the isolation and counting of PBMCs.

REPROCELL: What makes our biobank stand out?
04 August 2022
Disocver REPROCELL, a leader in its industry located in Maryland that is home to over 600,000 biospecimens collected from approximately 120,000 donors.

Ultimate guide to nonanimal cardiovascular safety pharmacology
03 August 2022
Discover examples of receptors that are flagged during receptor binding studies and which can then be explored through functional assays.

Everything you need to know about the 5-HT2B receptor
01 July 2022
Explore the key physiological and pharmacological features of the 5-HT2B receptor plus its long and complicated relationship with cardiotoxicity.

Limitations of the isolated perfused heart and alternative models
24 May 2022
Discover the various limitations of the isolated perfused heart model, and human, ex vivo alternatives you can incorporate into your research instead.

Everything we know about the 5-HT2A (serotonin) receptor
04 May 2022
Read our ultimate guide to the 5-HT2A serotonin receptor. Discover the pharmacology and physiology of 5-HT2A in the nervous and cardiovascular systems.

Everything we know about the 5-HT1B receptor
21 April 2022
Discover everything scientists know, so far, about the pharmacology, molecular structure, and function of the human 5HT1B and 5HT1D receptor.

Skin biopsy and ex vivo culture methods
29 March 2022
Looking for skin biopsy and ex vivo culture methods to use in your research? Discover a range of ex vivo and in vitro skin models outlined in this article.

The influence of the microbiome on inflammatory bowel disease
18 March 2022
Learn about the the influence of the gut microbiome on inflammatory bowel disease (IBD) and how precision medicine may change the way we treat IBD.

What is Human Tissue Testing?
14 March 2022
Discover the definition of human tissue testing and how it can enhance your drug discovery research on the REPROCELL blog.

REPROCELL Solutions for Skin Disease Researchers
04 March 2022
Looking to outsource your skin disease research? Discover REPROCELL's range of solutions for skin disease researchers today.
![Predicting Psoriasis Drug Efficacy in Human Skin [INFOGRAPHIC]](https://www.reprocell.com/hs-fs/hubfs/07AUG20%20human%20skin%20microscopy%20histology%20cross%20section-1.jpeg?width=756&height=425&name=07AUG20%20human%20skin%20microscopy%20histology%20cross%20section-1.jpeg)
Predicting Psoriasis Drug Efficacy in Human Skin [INFOGRAPHIC]
03 March 2022
View our infographic and discover how REPROCELL scientists helped Pharma to predicting psoriasis drug efficacy in human skin biopsies.

How SynFire® Technology can benefit your research
03 March 2022
SynFire neural cells more closely resemble real human biology than many other iPSC-based systems, resulting in better prediction of compound behaviour.

Inserts or plates for your 3D cell culture?
28 February 2022
Struggling to decide between inserts or plates for your 3D cell culture? Visit our blog and discover how to choose the best 3D system for your research.

How to improve your 3D Cell Culture using Small-scale Perfusion Systems
15 February 2022
Discover how to improve your 3D cell culture using small-scale perfusion systems on the REPROCELL blog.

Enhance your epithelial barriers assay using Alvetex®
07 February 2022
Looking to improve the translatability of your epithelial models? Find out how to enhance your epithelial barriers assay using Alvetex.

Everything you need to know about the REPROCELL iPSC Biobank
30 November 2021
Interested in learning about our off-the-shelf iPSCs? Read our blog article and discover everything you need to know about the REPROCELL iPSC Biobank.

How we established an in vitro Parkinson’s Disease model
24 November 2021
Discover how to establish an in vitro Parkinson’s Disease model using iPSC-derived neurons - from patient screening to neuronal maturation.

How digital droplet PCR can improve CRISPR gene editing (with examples)
05 October 2021
Looking to understand how digital PCR can improve your genome editing projects? Learn how digital PCR can improve your CRISPR gene editing (with examples).

What is digital droplet PCR and how can it improve stem cell therapies?
13 September 2021
Discover the definition of digital droplet PCR and how can it improve the safety of your stem cell therapies.

The ultimate guide to REPROCELL’s GMP iPSC manufacturing service
09 September 2021
Find out everything you need to know about REPROCELL's clinical stem cell services in our ultimate guide to REPROCELL’s GMP iPSC manufacturing service.

The ultimate guide to REPROCELL’s stem cell research services
16 August 2021
Looking to outsource your stem cell research project? Discover everything you need to know in our ultimate guide to REPROCELL’s stem cell research services

Will mRNA change medicine for good?
12 August 2021
Find out if mRNA will change medicine for good. Read about the molecules rise to fame in 2020 and how it could be used to treat diseases such as cancer.

Our top 10 stem cell culture products
02 July 2021
Read our countdown of the op 10 stem cell culture products sold by REPROCELL as chosen by our customers.

Human tissue testing and precision medicine
08 June 2021
Find out how a recent nature article has sparked interest in the use of human tissue testing for precision medicine.

The ultimate guide to Alvetex
31 May 2021
Find out everything you need to know about Alvetex technology in our ultimate guide to Alvetex.

How to bioengineer epithelial tissues in vitro
25 May 2021
Looking to bioengineer epithelial tissues in vitro? Find out how Alvetex can be used to create full-thickness epithelial tissues on the REPROCELL blog.

Improving precision medicine strategies with human tissue testing
29 April 2021
Discover how you can improve your precision medicine strategies with human tissue testing.

Precision medicine for the COVID-19 pandemic
03 February 2021
Learn how precision medicine could help to end the COVID-19 pandemic by accelerating the processes of understanding and treating disease.

Protocol for immunocytochemistry of stem cells
29 January 2021
Read our tried-and-tested protocol for immunocytochemistry of stem cells and optimize your antibody concentrations.

Five reasons to choose StemRNA 3rd Gen Reprogramming Technology
04 December 2020
Looking for a more efficient iPSC reprogramming kit? Discover five reasons you should choose StemRNA 3rd Gen Reprogramming Technology for iPSC generation.

What is Translational Science?
11 September 2020
Discover the definition of translational research and how it can improve drug discovery and development programs.
![This light-activated treatment could help patients with peripheral artery disease [INTERVIEW]](https://www.reprocell.com/hs-fs/hubfs/07AUG20%20heart%20disease%20blockage%20blood%20vessel%20fat%20deposit.jpeg?width=756&height=425&name=07AUG20%20heart%20disease%20blockage%20blood%20vessel%20fat%20deposit.jpeg)
This light-activated treatment could help patients with peripheral artery disease [INTERVIEW]
01 September 2020
Discover how this light-activated treatment could help patients with peripheral artery disease in this interview with the researchers.

4 Examples of human models of respiratory diseases
03 August 2020
Looking for human models of respiratory diseases? Find 4 examples of translational respiratory disease models on the REPROCELL blog.

Using 3D culture to improve Caco-2 permeability assays
14 July 2020
Looking to elevate your permeability projects? Find out how you can use 3D culture to improve your Caco-2 permeability assays from REPROCELL.

CRISPR-Cas9: Big Data, Precision Medicine and Universal Cell Therapy
13 April 2020
Find out how CRISPR-Cas9 can enhance big data, precision medicine, and universal cell therapy on the REPROCELL blog.

How to Characterize the Barrier Properties of Alvetex®-Based Mucosal Models
06 April 2020
Find out how to Characterize the Barrier Properties of your Alvetex®-Based Mucosal Models on the REPROCELL blog.

How CRISPR-SNIPER compares to other gene editing techniques
01 April 2020
Want to find out how CRISPR-SNIPER compares to other gene editing techniques? Discover the benefits of this advanced editing system on the REPROCELL blog.
![A Visual Guide to CRISPR-SNIPER Gene Editing [INFOGRAPHIC]](https://www.reprocell.com/hs-fs/hubfs/07AUG20%20crispr%20cas%20gene%20editing%20dna.jpeg?width=756&height=425&name=07AUG20%20crispr%20cas%20gene%20editing%20dna.jpeg)
A Visual Guide to CRISPR-SNIPER Gene Editing [INFOGRAPHIC]
30 March 2020
Discover the benefits of our advanced genome editing system in this visual guide to CRISPR-SNIPER gene editing [INFOGRAPHIC].
![How is Stemchymal® performing in Clinical Trials? [INFOGRAPHIC]](https://www.reprocell.com/hs-fs/hubfs/21JAN20%20Mesnchymal%20Stem%20Cells%20MSC-1.jpeg?width=756&height=425&name=21JAN20%20Mesnchymal%20Stem%20Cells%20MSC-1.jpeg)
How is Stemchymal® performing in Clinical Trials? [INFOGRAPHIC]
16 March 2020
Wondering how is Stemchymal® performing in Clinical Trials? Discover the main findings from Stemchymal's clinical trials in our infographic.

3 challenges facing the introduction of iPSC-derived therapies
12 February 2020
Discover three of the main challenges facing the introduction of iPSC-derived therapies on the REPROCELL blog.

4 ways stem cells can be used in medical treatments
12 February 2020
Looking to find out how stem cells be used in medical treatments? Find 4 ways stem cells can be used therapeutically on the REPROCELL blog.

5 Benefits of Precision Medicine
07 February 2020
Find out the top 5 benefits of precision medicine, to drug developers to patients, on the REPROCELL blog.

4 reasons human tissues should be used to predict drug bioavailability
29 January 2020
Find out why human tissues should be used to predict drug bioavailability and permeability on the REPROCELL blog.

How to estimate drug permeability using the Ussing Chamber technique
22 January 2020
Looking to estimate drug permeability using the Ussing Chamber technique? Find out how on the REPROCELL blog.

Cost Effective, Lab-scale Spheroid Culture of iPSCs
21 January 2020
Looking for cost effective, lab-scale, spheroid culture of iPSCs? Discover how the ABLE Bioreactor enables smarter cell production - no experience needed.

4 TED Talks discussing the future of regenerative medicine
19 December 2019
Learn about the current limitations facing the future of regenerative medicine through these four TED Talks.

Stem cells offer hope for sufferers of Spinocerebellar Ataxia
08 November 2019
Discover how stem cell treatments can offer hope for sufferers of Spinocerebellar Ataxia (SCA).

How to mass culture induced pluripotent stem cells (iPSCs)
30 October 2019
Discover how to mass culture induced pluripotent stem cells (iPSCs) using a reactor culture system on the REPROCELL blog.

Improve Gene-Editing Success with CRISPR-SNIPER Technology
29 October 2019
The Ultimate Guide to CRISPR-SNIPER technology: a gene-editing system that overcomes the limitations of conventional CRISPR systems.

What are the advantages of an internship to employers?
23 October 2019
Find out the advantages of an internship to employers on the REPROCELL blog. Discover how hiring an intern can benefit your company and employees.

Which stem cell reprogramming technology should I use?
17 October 2019
Wondering which stem cell reprogramming technology you should use for your iPSC project? Discover the pros and cons of RNA Reprogramming from REPROCELL.

IBDiscovery: Combining patient and drug discovery data to transform healthcare
16 September 2019
Learn how REPROCELL's IBDisocvery project is combining patient and drug discovery data to transform healthcare.

What is CRISPR-SNIPER Gene Editing?
02 September 2019
Discover the definition of CRISPR-SNIPER and how this advanced gene editing system can improve your edits.

Machine Learning and Big Data in Precision Medicine
08 August 2019
Discover how machine learning and big data can be used in precision medicine to cut costs, reduce errors and gain faster drug approvals.

Pluripotent Potential for Clinical Application
25 July 2019
Discover the potential of induced pluripotent stem cells (iPSCs) for clinical application on the REPROCELL blog.

An Improved Model for IBD Drug Discovery
11 July 2019
Looking to find an improved model for IBD drug discovery? Find out the benefits of human tissue testing on the REPROCELL blog.

Advances in diagnostics, treatments, and frontiers of research in IBD
13 June 2019
Find out the latest advances in diagnostics, treatments, and frontiers of research in IBD on the REPROCELL blog.

How Human Organoculture can Improve Precision Medicine Strategies
05 June 2019
Discover how human organoculture can be used to improve precision medicine strategies on the REPROCELL blog.

Will The Microbiome Become The Next Hot Topic For Cancer Research?
16 May 2019
Discover whether the microbiome will become the next hot topic for cancer research on the REPROCELL blog.

REPROCELL Solutions for Respiratory Disease Researchers
29 April 2019
Looking to outsource your respiratory disease research? Find out more about REPROCELL's solutions for respiratory disease researchers.

Stem Cells for Autism
03 April 2019
Visit the REPROCELL blog and find out how stem cells could be used to treat autism in the future.

Neurite Outgrowth Assays using StemRNA Neuro
20 March 2019
Find out more about REPROCELL's neurite outgrowth assay that uses StemRNA Neuro cells.

Using human iPSCs as an in vitro model for regenerative medicine and disease modelling
22 February 2019
The conventional drug discovery pathway is a very inefficient process with the majority of candidate drugs not reaching the market due to safety and/or efficacy issues. But the use of iPSCs allows high throughput screening of therapies and disease-specific treatment using patient-specific models.

The gut microbiome in health and disease: the future for diagnosis and treatment of IBD and IBS?
12 February 2019
Discover whether the gut microbiome, in health and disease, is the future for diagnosis and treatment of IBD and IBS on the REPROCELL blog.

Tissue Sourcing for the Development of iPSC-derived Disease Models
06 February 2019
Looking to source primary tissues for iPSC generation? Find out more about tissue sourcing for the development of iPSC-derived disease models.

REPROCELL Solutions for Gastrointestinal Researchers
25 October 2018
Looking to outsource your gastrointestinal research? Find out more about REPROCELL's service solutions for gastrointestinal researchers.

How animal testing is inaccurate and the alternatives
25 May 2018
Find out how animal experimentation can lead to adverse drug effects on the REPROCELL blog.

Human Tissue Testing in Drug Discovery and Development
27 March 2018
Discover how human tissue testing can be used in drug discovery and development to make the process smarter and more efficient.

Xeno-free culture of stem cells in NutriStem® hPSC XF medium
05 February 2018
Find out more information about the xeno-free culture of stem cells using NutriStem® hPSC XF medium.