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The REPROCELL Blog

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Latest Posts

Why PBMCs matter in gene and cell therapies

Why PBMCs matter in gene and cell therapies

Explore the vital role of PBMCs in gene therapy and translational research, highlighting their importance in understanding immune responses and treatment efficacy.

23 July 2026

Empowering the Future of Gene Editing with StemEdit OC-1 Protein

Empowering the Future of Gene Editing with StemEdit OC-1 Protein

Discover the innovative StemEdit OC-1 Protein, a generative AI-designed gene-editing enzyme that enhances genome engineering with improved safety and efficiency.

20 July 2026

Induced Pluripotent Stem Cells: History and A Look Back

Induced Pluripotent Stem Cells: History and A Look Back

Explore the fascinating history of induced pluripotent stem cells, from early research milestones to recent advancements in cellular reprogramming techniques.

16 July 2026

From Biospecimen to Insight: How Human Tissue Improves Translational Confidence Bridging the Translational Gap in Drug Discovery

From Biospecimen to Insight: How Human Tissue Improves Translational Confidence Bridging the Translational Gap in Drug Discovery

Explore how human tissue models enhance drug discovery by bridging the gap between preclinical findings and clinical success, improving translational confidence.

25 June 2026

Streamlining PBMC Processing for Reliable Results in Multi-Site Clinical Trials: Key Challenges and Solutions

Streamlining PBMC Processing for Reliable Results in Multi-Site Clinical Trials: Key Challenges and Solutions

Explore the challenges and solutions in PBMC processing for multi-site clinical trials, ensuring reliable results and data integrity for research success.

11 June 2026

Featured Posts

Why PBMCs matter in gene and cell therapies

Why PBMCs matter in gene and cell therapies

Explore the vital role of PBMCs in gene therapy and translational research, highlighting their importance in understanding immune responses and treatment efficacy.

23 July 2026

Empowering the Future of Gene Editing with StemEdit OC-1 Protein

Empowering the Future of Gene Editing with StemEdit OC-1 Protein

Discover the innovative StemEdit OC-1 Protein, a generative AI-designed gene-editing enzyme that enhances genome engineering with improved safety and efficiency.

20 July 2026

Induced Pluripotent Stem Cells: History and A Look Back

Induced Pluripotent Stem Cells: History and A Look Back

Explore the fascinating history of induced pluripotent stem cells, from early research milestones to recent advancements in cellular reprogramming techniques.

16 July 2026

From Biospecimen to Insight: How Human Tissue Improves Translational Confidence Bridging the Translational Gap in Drug Discovery

From Biospecimen to Insight: How Human Tissue Improves Translational Confidence Bridging the Translational Gap in Drug Discovery

Explore how human tissue models enhance drug discovery by bridging the gap between preclinical findings and clinical success, improving translational confidence.

25 June 2026

Streamlining PBMC Processing for Reliable Results in Multi-Site Clinical Trials: Key Challenges and Solutions

Streamlining PBMC Processing for Reliable Results in Multi-Site Clinical Trials: Key Challenges and Solutions

Explore the challenges and solutions in PBMC processing for multi-site clinical trials, ensuring reliable results and data integrity for research success.

11 June 2026

AI-Designed CRISPR Enables Hypoimmune iPSC Engineering for Off-the-Shelf Cell Therapy

AI-Designed CRISPR Enables Hypoimmune iPSC Engineering for Off-the-Shelf Cell Therapy

REPROCELL's StemEdit platform enables the creation of hypoimmune iPSCs for scalable off-the-shelf cell therapies, reducing immune rejection and enhancing patient access.

04 June 2026

What Are Off-Target Effects in Cellular Gene Editing? Risks, Detection, and Solutions

What Are Off-Target Effects in Cellular Gene Editing? Risks, Detection, and Solutions

Explore off-target effects in gene editing, from CRISPR risks and AI-driven detection to genomic safety in iPSC therapies.

20 May 2026

What to Look for in a Global Central Lab Partner for Clinical Trials

What to Look for in a Global Central Lab Partner for Clinical Trials

Selecting the right global central lab partner is crucial for clinical trial success, impacting data quality, logistics, and regulatory compliance.

14 May 2026

The Resurgence of New Approach Methodologies (NAMs) in Drug Discovery and Safety Assessment

The Resurgence of New Approach Methodologies (NAMs) in Drug Discovery and Safety Assessment

Explore how New Approach Methodologies are revolutionizing drug discovery and safety assessment by enhancing human-relevant research and reducing reliance on animal testing.

30 April 2026

Inside the Sample Lifecycle: How Central Labs Protect Data from Collection to Analysis

Inside the Sample Lifecycle: How Central Labs Protect Data from Collection to Analysis

Explore how central laboratories safeguard data integrity throughout the sample lifecycle, from collection to analysis, ensuring reliable outcomes in research.

13 April 2026

Mapping the Competitive Landscape of Human Tissue-Based Drug Discovery

Mapping the Competitive Landscape of Human Tissue-Based Drug Discovery

Explore how REPROCELL leads in human tissue-based drug discovery, addressing market gaps and offering innovative, disease-relevant solutions for better therapeutic outcomes.

02 April 2026

5 Hard Truths About Bringing Stem Cell Therapies to the Clinic

5 Hard Truths About Bringing Stem Cell Therapies to the Clinic

Discover the essential truths behind developing clinical-grade stem cell therapies and learn how to navigate the complexities of GMP manufacturing successfully.

30 March 2026

Donor Variability in Ex Vivo Human Tissue Studies: Challenge, Feature, or Translational Advantage

Donor Variability in Ex Vivo Human Tissue Studies: Challenge, Feature, or Translational Advantage

Explore how donor variability in ex vivo human tissue studies enhances translational research by providing insights into patient heterogeneity and improving drug discovery.

12 March 2026

REPROCELL Attends Japan-Maryland Night 2026

REPROCELL Attends Japan-Maryland Night 2026

REPROCELL was honored to attend Japan-Maryland Night on Wednesday March 4th 2026  Maryland State, USA, hosted by the Embassy of Japan (in Washington DC).

06 March 2026

From StemRNA™ Clinical Seed Clone to GMP-Ready Cell Therapy Programs

From StemRNA™ Clinical Seed Clone to GMP-Ready Cell Therapy Programs

Discover how REPROCELL’s StemRNA™ Clinical iPSC Seed Clones streamline the path to GMP-ready cell therapy, simplifying regulatory processes and enabling scalable, high-quality manufacturing.

27 February 2026

Preserving the Microenvironment-Advances in Ex Vivo Colonic Tissue Culture for IBD Drug Discovery

Preserving the Microenvironment-Advances in Ex Vivo Colonic Tissue Culture for IBD Drug Discovery

Advances in ex vivo colonic tissue culture preserve the microenvironment, enhancing IBD drug discovery by maintaining native tissue architecture and immune complexity for more predictive research models.

26 February 2026

Integrating AI with Ex Vivo Data: How Machine Learning Is Enhancing Predictive Accuracy in Human Tissue Studies

Integrating AI with Ex Vivo Data: How Machine Learning Is Enhancing Predictive Accuracy in Human Tissue Studies

Discover how integrating AI with ex vivo human tissue data is revolutionizing drug discovery by enhancing predictive accuracy and bridging the gap between preclinical and clinical research.

12 February 2026

The Critical Role of Central Laboratory Services in Regulatory Compliance and Data Integrity

The Critical Role of Central Laboratory Services in Regulatory Compliance and Data Integrity

Explore the critical role of Central Laboratory Services in ensuring data integrity and regulatory compliance in drug development. Learn how CLS supports reliable, reproducible, and auditable data.

27 January 2026

Modeling Fibrosis Progression Ex Vivo: Opportunities for Anti-Fibrotic Drug Screening

Modeling Fibrosis Progression Ex Vivo: Opportunities for Anti-Fibrotic Drug Screening

Explore the benefits of ex vivo human tissue models for fibrosis research and anti-fibrotic drug screening, offering a more accurate alternative to conventional preclinical methods.

15 January 2026

OpenCRISPR-1: The First AI-Designed CRISPR Editor for High-Precision Gene & Cell Therapy

OpenCRISPR-1: The First AI-Designed CRISPR Editor for High-Precision Gene & Cell Therapy

Discover OpenCRISPR-1 — the first fully AI-designed CRISPR–Cas editor. Built by generative large language model, it enables high-efficiency, high-specificity genome and base editing in human cells. Ideal for cell therapy, stem-cell research, and advanced gene-editing workflows.

16 December 2025

Enhancing Experimental Precision with the Alvetex® Advanced Culture System

Enhancing Experimental Precision with the Alvetex® Advanced Culture System

Discover how Alvetex® Advanced enhances experimental precision with its flexible and functional 3D culture system for creating biologically accurate human skin models.

04 December 2025

iPSC-, MSC- and iMSC-Derived Exosome Therapeutics: The Cell-Free Future of Regenerative Medicine

iPSC-, MSC- and iMSC-Derived Exosome Therapeutics: The Cell-Free Future of Regenerative Medicine

Explore the future of regenerative medicine with iPSC-, MSC-, and iMSC-derived exosome therapeutics, focusing on their advantages, challenges, and clinical potential.

19 November 2025

Using Ex Vivo Skin Explants to Study Local Immune Responses in Psoriasis and Atopic Dermatitis

Using Ex Vivo Skin Explants to Study Local Immune Responses in Psoriasis and Atopic Dermatitis

Explore the use of ex vivo skin explants to study local immune responses in chronic inflammatory skin diseases like psoriasis and atopic dermatitis.

17 November 2025

The Enduring Value of Organ Baths in Modern Drug Discovery

The Enduring Value of Organ Baths in Modern Drug Discovery

Discover the enduring value of organ baths in drug discovery and their critical role in ensuring the efficacy and safety of new therapies.

06 November 2025

REPROCELL’s Global Biorepository, the solution to your human tissue sample requirements

REPROCELL’s Global Biorepository, the solution to your human tissue sample requirements

Our biorepository's carefully governed infrastructure ensures specimens are collected, processed, stored, and distributed under rigorous, standardized conditions.

23 October 2025

How Human Tissue Testing Adds Commercial Value for Shareholders

How Human Tissue Testing Adds Commercial Value for Shareholders

Discover how human tissue testing enhances shareholder value, exploring its impact on drug discovery, precision medicine, and regenerative medicine within the life sciences industry.

03 September 2025

Current Landscape of FDA Stem Cell Approvals and Trials 2023-2025

Current Landscape of FDA Stem Cell Approvals and Trials 2023-2025

Discover the latest advancements and FDA approvals in stem cell therapies, including iPSC and MSC treatments, reshaping the 2023-2025 clinical landscape.

02 September 2025

NIH Announces End to Exclusive Funding for Animal Model Research

NIH Announces End to Exclusive Funding for Animal Model Research

NIH ends exclusive funding for animal model research, promoting New Approach Methodologies like organ-on-a-chip systems and human tissue testing.

18 August 2025

Revolutionizing IBD Research with Innovative In Vitro Models

Revolutionizing IBD Research with Innovative In Vitro Models

Catch a glimpse into the future of inflammatory bowel disease (IBD) research with our ground breaking in vitro models.

11 August 2025

Why Early Genetic Variant Detection in iPSC Cultures Is Critical for Safe and Regulatory-Compliant Cell Therapies

Why Early Genetic Variant Detection in iPSC Cultures Is Critical for Safe and Regulatory-Compliant Cell Therapies

Explore the crucial role of early genetic variant detection in iPSC cultures for ensuring safe, effective, and regulatory-compliant cell therapies. Learn about risk profiling and REPROCELL’s solutions.

01 August 2025

Subcutaneous Artery Assays Help Us to Understand Blood Pressure Regulation

Subcutaneous Artery Assays Help Us to Understand Blood Pressure Regulation

Explore how subcutaneous artery assays enhance understanding of blood pressure regulation and aid in the development of safer, more effective cardiovascular drugs.

07 July 2025

Able Biott Single-use Bioreactors Enhance the Development of Disease Models and Cell Therapy

Able Biott Single-use Bioreactors Enhance the Development of Disease Models and Cell Therapy

Discover how Able Biott single-use bioreactors enhance disease modeling and cell therapy development through scalable, efficient iPSC culture solutions.

03 July 2025

Why mRNA Reprogramming Is the Key to Safer and Faster iPSC Generation?

Why mRNA Reprogramming Is the Key to Safer and Faster iPSC Generation?

Discover how mRNA reprogramming enhances the safety, efficiency, and scalability of iPSC generation for therapeutic applications. Explore REPROCELL's innovative technologies and services.

10 June 2025

New Therapeutic Targets: The Role of IL17-Related Genes in Precision Medicine

New Therapeutic Targets: The Role of IL17-Related Genes in Precision Medicine

Discover how IL-17 related genes could revolutionize psoriasis treatment, offering new therapeutic targets and paving the way for precision medicine advancements.

09 June 2025

Balancing Efficacy and Cognitive Health In Bladder Assays

Balancing Efficacy and Cognitive Health In Bladder Assays

New approaches in OAB treatment focus on balancing efficacy and cognitive health, using alternatives to anticholinergics and personalized medicine to improve patient outcomes.

23 May 2025

Breaking Barriers in Women’s Health: The World’s First Live Birth Using Fertilo

Breaking Barriers in Women’s Health: The World’s First Live Birth Using Fertilo

Discover how Gameto achieved the world’s first live birth using Fertilo, a revolutionary in vitro oocyte maturation technology. Learn about its stem cell-driven innovation and how it's transforming fertility care for women worldwide.

21 May 2025

Key Strategies Central Labs Use to Fast-Track Time to Market

Key Strategies Central Labs Use to Fast-Track Time to Market

Learn how central labs use automation, outsourcing, and AI to accelerate drug development, reduce costs, and improve clinical trial accuracy and efficiency.

21 May 2025

Key Challenges in Clinical iPSC Applications: How REPROCELL Helps You Succeed

Key Challenges in Clinical iPSC Applications: How REPROCELL Helps You Succeed

Overcome key challenges in clinical iPSC applications with REPROCELL's ethical sourcing, advanced reprogramming, and tailored solutions for reliable, scalable therapies.

12 May 2025

Epigenetic Modifications: Their Role in iPSC Reprogramming and Differentiation

Epigenetic Modifications: Their Role in iPSC Reprogramming and Differentiation

Explore the critical role of epigenetic mechanisms like DNA methylation and histone modifications in iPSC reprogramming and differentiation. Learn how optimizing epigenetic stability enhances reprogramming efficiency, reduces variability, and ensures safer, more reliable iPSC applications for research and therapy.

02 May 2025

REPROCELL Connects with Maryland Governor Moore During His Japan Visit

REPROCELL Connects with Maryland Governor Moore During His Japan Visit

Maryland Governor Moore strengthens biotech ties with Japan, highlighting REPROCELL's pivotal role in the Maryland-Kanagawa partnership during his trade mission.

22 April 2025

Exosomes from Stem Cells: iPSC vs. MSC-Derived Exosomes for Aesthetic and Regenerative Medicine

Exosomes from Stem Cells: iPSC vs. MSC-Derived Exosomes for Aesthetic and Regenerative Medicine

Discover how iPSC and MSC-derived exosomes revolutionize skin rejuvenation and anti-aging treatments in aesthetic medicine. Main Point Summary: The blog explores the potential of exosomes derived from induced pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs) for skin rejuvenation and anti-aging treatments in aesthetic medicine, comparing their effectiveness, mechanisms, and applications.

14 April 2025

Can Stem Cells Revolutionize Sustainable Food Production?

Can Stem Cells Revolutionize Sustainable Food Production?

Discover how stem cell technology is transforming sustainable food production, offering ethical and scalable alternatives to conventional meat, dairy, and seafood.

31 March 2025

Advancing Clinical Research Through Patient Engagement: The Impact of Tissue Biopsy Donation

Advancing Clinical Research Through Patient Engagement: The Impact of Tissue Biopsy Donation

Discover how patient engagement and tissue biopsy donation are revolutionizing clinical research, enhancing personalized medicine, and fostering deeper collaboration between researchers and patients.

19 March 2025

Qkineʼs Animal-Free Growth Factors and Cytokines are ideal for Stem Cell Culture

Qkineʼs Animal-Free Growth Factors and Cytokines are ideal for Stem Cell Culture

Qkine's growth factors and cytokines are of exceptional bioactivity and purity - essential for maintaining and differentiating stem cell cultures.

07 March 2025

Prince George’s County Economic Development Corporation Visits REPROCELL USA

Prince George’s County Economic Development Corporation Visits REPROCELL USA

REPROCELL USA hosts Prince George's County Economic Development Corporation, showcasing their biotech services and highlighting the benefits of operating in PG County.

03 March 2025

The Therapeutic Advantage of Induced Pluripotent Stem Cells-Derived Mesenchymal Stem Cells (iMSCs)

The Therapeutic Advantage of Induced Pluripotent Stem Cells-Derived Mesenchymal Stem Cells (iMSCs)

Discover the clinical benefits and advancements of using induced pluripotent stem cells-derived mesenchymal stem cells (iMSCs) in regenerative medicine and therapeutic applications.

24 February 2025

REPROCELL Makes its First Appearance at Japan-Maryland Night

REPROCELL Makes its First Appearance at Japan-Maryland Night

REPROCELL made its debut at Japan-Maryland Night, fostering connections with political and scientific communities to further its mission and showcase its genomic services.

18 February 2025

How Biomarkers Are Shaping the Future of Skin Disease Treatment

How Biomarkers Are Shaping the Future of Skin Disease Treatment

Discover how biomarkers are revolutionizing the treatment of skin diseases by enabling more precise and effective therapies.

04 February 2025

Redefining Success in IBD Drug Discovery with Human Tissue Models

Redefining Success in IBD Drug Discovery with Human Tissue Models

Redefining IBD drug discovery with a dual-pronged approach through human bioengineered and fresh tissue.

11 December 2024

Pharma AI is Changing Clinical Trials by Optimizing Patient Selection

Pharma AI is Changing Clinical Trials by Optimizing Patient Selection

AI is revolutionizing clinical trials by optimizing patient selection, improving trial outcomes, and accelerating the development of new drugs.

27 November 2024

REPROCELL's Advanced Skin Tissue Engineering

REPROCELL's Advanced Skin Tissue Engineering

Discover REPROCELL's pioneering 3D skin tissue engineering, enhancing drug development and skincare research with accurate and robust human skin models.

31 October 2024

Plasma or Serum? – You Decide

Plasma or Serum? – You Decide

Discover the key differences between plasma and serum, their collection methods, and their impact on clinical and experimental outcomes.

17 October 2024

From Fibroblasts to Cancer-Attacking Cells: Insights from Recent Research on Natural Killer Cells Derived from Clinical Grade iPSCs

From Fibroblasts to Cancer-Attacking Cells: Insights from Recent Research on Natural Killer Cells Derived from Clinical Grade iPSCs

Discover the differentiation potential of induced pluripotent stem cells (iPSC) to cytotoxic NK cells, including recent advancements in research and therapy.

16 October 2024

The Power of Human Tissue Models in Preclinical Research

The Power of Human Tissue Models in Preclinical Research

Discover how human tissue models are transforming drug safety assessments and improving outcomes in preclinical research through real-world case studies.

03 October 2024

What you should know about the FDA’s Biological License Application Process

What you should know about the FDA’s Biological License Application Process

Learn about the FDA's Biological License Application process, including submission requirements, review phases, and expedited pathways for biologics approvals.

19 September 2024

High Prevalence of BRCA Mutations in Indian Breast Cancer Patients: Insights from a Diagnostic Lab

High Prevalence of BRCA Mutations in Indian Breast Cancer Patients: Insights from a Diagnostic Lab

High prevalence of BRCA mutations in Indian breast cancer patients underscores the need for tailored genetic testing and early detection strategies.

09 September 2024

Understanding Safety Pharmacology in Human Tissues

Understanding Safety Pharmacology in Human Tissues

Explore the role of safety pharmacology in drug discovery, and the importance of human tissue studies for predicting and mitigating potential effects.

26 August 2024

Breaking Ground in Alzheimer’s Research: A New Path to Drug Discovery and Personalized Medicine

Breaking Ground in Alzheimer’s Research: A New Path to Drug Discovery and Personalized Medicine

Breaking new ground in Alzheimer's research, a study by Durham University uncovers potential therapeutic targets using advanced stem cell technology.

22 August 2024

Nucleic Acid Extraction in Clinical Research

Nucleic Acid Extraction in Clinical Research

REPROCELL is revolutionizing drug discovery in clinical research through nucleic acid extraction.

08 August 2024

Embracing Every Career Pathway with #NoWrongPath

Embracing Every Career Pathway with #NoWrongPath

This year, we took part in the social media movement #NoWrongPath. Discover our colleagues inspiring story about how he got to where he is today!

06 August 2024

Need To Conduct a Multi-Variable Study? REPROCELL Can Help with That!

Need To Conduct a Multi-Variable Study? REPROCELL Can Help with That!

Conducting a multi-variable study on cancer risk and family history? Discover how our biorepository and custom collections can assist in your research.

18 July 2024

AI in Drug Discovery: The Role of SHAP in Pharmacology

AI in Drug Discovery: The Role of SHAP in Pharmacology

Learn how Explainable AI, like SHAP, is transforming drug discovery by providing transparency and clarity in machine learning models.

11 July 2024

Custom Oligosynthesis: Tailoring Solutions for Specific Research Needs

Custom Oligosynthesis: Tailoring Solutions for Specific Research Needs

Custom oligosynthesis offers tailored solutions for specific research needs, enhancing genetic research, diagnostics, and therapeutics.

27 June 2024

Engineered Pigmented Skin Equivalents Reveal UV Protection Mechanisms

Engineered Pigmented Skin Equivalents Reveal UV Protection Mechanisms

Discover how engineered pigmented skin equivalents reveal UV protection mechanisms and offer insights into skin health at a molecular level.

18 June 2024

Harnessing Functional Genomics to Revolutionize Inflammatory Bowel Disease Treatment

Harnessing Functional Genomics to Revolutionize Inflammatory Bowel Disease Treatment

Discover how functional genomics is transforming IBD treatment with groundbreaking research on ETS2's role in inflammation.

07 June 2024

REPROCELL USA Inaugurates New GMP Laboratory

REPROCELL USA Inaugurates New GMP Laboratory

May 15, 2024: REPROCELL USA inaugurated its new GMP BioManufacturing Lab. The facility enables hiPSC and hMSC generation in a contaminant-free environment.

07 June 2024

Harnessing the Power of Mesenchymal Stem Cells

Harnessing the Power of Mesenchymal Stem Cells

Discover the groundbreaking potential of Mesenchymal Stem Cells (MSCs) in biomedical research and therapeutic development.

27 May 2024

What to consider when selecting a central laboratory services provider

What to consider when selecting a central laboratory services provider

There are a lot of factors to take into consideration when choosing a central laboratory service. Let's walk through them together.

07 May 2024

Leveraging Human Tissue Models with Preclinical and Drug Discovery CRO

Leveraging Human Tissue Models with Preclinical and Drug Discovery CRO

Our Preclinical and Drug Discovery CRO is transforming the landscape of drug development with new technologies and ethically sourced human tissue models.

05 April 2024

ec23: A Promising ATRA Alternative for Advancing Stem Cell Research

ec23: A Promising ATRA Alternative for Advancing Stem Cell Research

Learn how ec23 acts as a improved alternative to ATRA.

13 December 2023

Quality Control: What is really in your hiPSC culture?

Quality Control: What is really in your hiPSC culture?

Whatever the goals of your project, a robust QC testing protocol assessing sterility, pluripotency, and genetic abnormalities, while maintaining sample identity, is critical.

11 December 2023

Exploring CHIR99021: The Key to Stem Cell Research and Beyond

Exploring CHIR99021: The Key to Stem Cell Research and Beyond

CHIR 99021 effects on Wnt/β-catenin pathway

20 November 2023

Data Privacy and Protection in AI for Precision Medicine

Data Privacy and Protection in AI for Precision Medicine

Discover how AI is revolutionizing data protection and security in precision medicine.

31 October 2023

Bias in AI for precision medicine

Bias in AI for precision medicine

Without proper and due consideration in the design and delivery of new therapies and diagnostics, there is a risk that biased datasets will skew outcomes towards certain groups.

02 October 2023

Outsourcing AI-assisted clinical trial analytics software: what to consider

Outsourcing AI-assisted clinical trial analytics software: what to consider

Outsourcing clinical trial analytics? Choose a vendor that prioritizes security, data quality, and model explainability.

29 August 2023

Editing B2M and CIITA to Create Hypoimmune Cell Lines for Cell Therapy

Editing B2M and CIITA to Create Hypoimmune Cell Lines for Cell Therapy

Gene editing is a viable approach for reducing immunogenicity of iPSC-derived therapeutic cells. The B2M and CIITA HLA-regulatory genes are good targets.

29 August 2023

Clinical trial analytics using AI: everything you need to know

Clinical trial analytics using AI: everything you need to know

Explore the power of clinical trial analytics in shaping healthcare. Learn about data insights, machine learning, bias, and ethical considerations

14 August 2023

Why do patients respond differently to drugs? AI may provide an answer

Why do patients respond differently to drugs? AI may provide an answer

Learn how artificial intelligence combined with human tissue testing could help us understand why patients respond to drugs differently.

05 May 2023

Wire myography: the ultimate guide (protocol included)

Wire myography: the ultimate guide (protocol included)

Learn how to measure the reactivity and functional response of arteries in the wire myograph system in our wire myograph protocol.

25 April 2023

Alternative testing methods covered by the FDA Modernization Act 2.0

Alternative testing methods covered by the FDA Modernization Act 2.0

Discover whether the FDA Modernization Act 2.0. will increase the use of non-animal, alternative testing methods in drug development.

06 March 2023

Everything you need to know about the motilin receptor

Everything you need to know about the motilin receptor

Explore the function, physiology, & pharmacology of the motilin receptor. Discover what models can be used to investigate motilin mimetics preclinically.

21 February 2023

Make a Difference with Fresh Residual Human Tissue Donation for Research – How to Get Involved!

Make a Difference with Fresh Residual Human Tissue Donation for Research – How to Get Involved!

Discover the importance of fresh human tissue to healthcare development. Explore some of the options to donate residual tissue to pharmaceutical research.

31 January 2023

Clinical Trials: An Evolutionary Perspective

Clinical Trials: An Evolutionary Perspective

Find out how clinical trial systems and processes have developed and evolved during human history.

18 January 2023

From rat aorta to resistance arteries: measuring vascular contractility

From rat aorta to resistance arteries: measuring vascular contractility

Explore how isolated blood vessels can be used to determine drug behavior and discover translational alternatives to measuring vascular tone in rat aorta.

16 January 2023

Recombinant Human Laminins and their Use in Cell Culture

Recombinant Human Laminins and their Use in Cell Culture

Discover the biological processes that laminin regulates. Learn more about the use of laminin in stem cell research and culture.

05 January 2023

Everything we know about resistance arteries

Everything we know about resistance arteries

Learn about the physiology of resistance arteries in health and disease. Discover why they are important for controlling blood flow to vital organs.

21 November 2022

Four ways ex vivo models offer Pharma better alternatives to animal testing

Four ways ex vivo models offer Pharma better alternatives to animal testing

Learn more about ex vivo models, and how these under-appreciated systems are helping Pharma reduce animal testing.

01 November 2022

How to isolate PBMCs from whole blood using density gradient centrifugation

How to isolate PBMCs from whole blood using density gradient centrifugation

Find out how to isolate PBMCs from whole blood samples using density gradient centrifugation a.k.a. the Ficoll Overlay method.

19 October 2022

REPROCELL’s Stemgent Brings mRNA Reprogramming to the Clinical Sector

REPROCELL’s Stemgent Brings mRNA Reprogramming to the Clinical Sector

Discover how REPROCELL has employed its StemRNA™ 4th Generation Reprogramming Technology to bring the power of mRNA reprogramming to the clinical sector.

14 October 2022

Everything we know about the human relaxin peptide family

Everything we know about the human relaxin peptide family

Discover the physiology and pharmacology of the human relaxin peptide family and their analogs. Learn about the role of human tissue in ex vivo research.

28 September 2022

Endogenous and exogenous affectors of uterine contractility

Endogenous and exogenous affectors of uterine contractility

Discover everything you need to know about ex vivo uterine contractility models. Learn about the use of uterine tissue in drug development and research.

27 September 2022

How human fresh tissue models are helping RCD405 achieve regulatory approval

How human fresh tissue models are helping RCD405 achieve regulatory approval

Discover how Arcede Pharma recently used human tissue testing to generate preclinical efficacy data for their compound RCD405.

17 August 2022

What are PBMCs? Everything you need to know about Peripheral Blood Mononuclear Cells

What are PBMCs? Everything you need to know about Peripheral Blood Mononuclear Cells

PBMC is short for Peripheral Blood Mononuclear Cell, or any blood cell with a single nucleus. Many of our immune cells are PBMCs, including lymphocytes.

10 August 2022

Protocol for buffy coat preparation from whole blood

Protocol for buffy coat preparation from whole blood

Read our simple, three-step protocol for buffy coat preparation from whole blood. Learn how you can isolate the buffy-coat from whole blood samples.

09 August 2022

Protocol for PBMC isolation from buffy coat samples

Protocol for PBMC isolation from buffy coat samples

Learn how to isolate Peripheral Blood Mononuclear Cells (PBMCs) from buffy coat samples. Discover a protocol for the isolation and counting of PBMCs.

09 August 2022

REPROCELL: What makes our human tissue biorepository stand out?

REPROCELL: What makes our human tissue biorepository stand out?

Disocver REPROCELL, a leader in its industry located in Maryland that is home to over 600,000 biospecimens collected from approximately 120,000 donors.

04 August 2022

The ultimate guide to non-animal cardiovascular safety pharmacology

The ultimate guide to non-animal cardiovascular safety pharmacology

Discover examples of receptors that are flagged during receptor binding studies and which can then be explored through functional assays.

03 August 2022

Everything you need to know about the 5-HT2B receptor

Everything you need to know about the 5-HT2B receptor

Explore the key physiological and pharmacological features of the 5-HT2B receptor plus its long and complicated relationship with cardiotoxicity.

01 July 2022

Limitations of the isolated perfused heart and alternative models

Limitations of the isolated perfused heart and alternative models

Discover the various limitations of the isolated perfused heart model, and human, ex vivo alternatives you can incorporate into your research instead.

24 May 2022

Everything we know about the 5-HT2A (serotonin) receptor

Everything we know about the 5-HT2A (serotonin) receptor

Read our ultimate guide to the 5-HT2A serotonin receptor. Discover the pharmacology and physiology of 5-HT2A in the nervous and cardiovascular systems.

04 May 2022

Everything we know about the 5-HT1B receptor

Everything we know about the 5-HT1B receptor

Discover everything scientists know, so far, about the pharmacology, molecular structure, and function of the human 5HT1B and 5HT1D receptor.

21 April 2022

Skin biopsy and ex vivo culture methods

Skin biopsy and ex vivo culture methods

Looking for skin biopsy and ex vivo culture methods to use in your research? Discover a range of ex vivo and in vitro skin models outlined in this article.

29 March 2022

The influence of the microbiome on inflammatory bowel disease

The influence of the microbiome on inflammatory bowel disease

Learn about the the influence of the gut microbiome on inflammatory bowel disease (IBD) and how precision medicine may change the way we treat IBD.

18 March 2022

What is Human Tissue Testing?

What is Human Tissue Testing?

Discover the definition of human tissue testing and how it can enhance your drug discovery research on the REPROCELL blog.

14 March 2022

REPROCELL Solutions for Skin Disease Researchers

REPROCELL Solutions for Skin Disease Researchers

Looking to outsource your skin disease research? Discover REPROCELL's range of solutions for skin disease researchers today.

04 March 2022

Predicting Psoriasis Drug Efficacy in Human Skin [Infographic]

Predicting Psoriasis Drug Efficacy in Human Skin [Infographic]

View our infographic and discover how REPROCELL scientists helped Pharma to predicting psoriasis drug efficacy in human skin biopsies.

03 March 2022

Inserts or plates for your 3D cell culture?

Inserts or plates for your 3D cell culture?

Struggling to decide between inserts or plates for your 3D cell culture? Visit our blog and discover how to choose the best 3D system for your research.

28 February 2022

How to improve your 3D Cell Culture using Small-scale Perfusion Systems

How to improve your 3D Cell Culture using Small-scale Perfusion Systems

Discover how to improve your 3D cell culture using small-scale perfusion systems on the REPROCELL blog.

15 February 2022

Enhance your epithelial barriers assay using Alvetex®

Enhance your epithelial barriers assay using Alvetex®

Looking to improve the translatability of your epithelial models? Find out how to enhance your epithelial barriers assay using Alvetex.

07 February 2022

Everything you need to know about the REPROCELL iPSC Biobank

Everything you need to know about the REPROCELL iPSC Biobank

Interested in learning about our off-the-shelf iPSCs? Read our blog article and discover everything you need to know about the REPROCELL iPSC Biobank.

30 November 2021

How we established an in vitro Parkinson’s Disease model

How we established an in vitro Parkinson’s Disease model

Discover how to establish an in vitro Parkinson’s Disease model using iPSC-derived neurons - from patient screening to neuronal maturation.

24 November 2021

How digital droplet PCR can improve CRISPR gene editing (with examples)

How digital droplet PCR can improve CRISPR gene editing (with examples)

Looking to understand how digital PCR can improve your genome editing projects? Learn how digital PCR can improve your CRISPR gene editing (with examples).

05 October 2021

What is digital droplet PCR and how can it improve stem cell therapies?

What is digital droplet PCR and how can it improve stem cell therapies?

Discover the definition of digital droplet PCR and how can it improve the safety of your stem cell therapies.

13 September 2021

The ultimate guide to REPROCELL’s GMP iPSC manufacturing service

The ultimate guide to REPROCELL’s GMP iPSC manufacturing service

Find out everything you need to know about REPROCELL's clinical stem cell services in our ultimate guide to REPROCELL’s GMP iPSC manufacturing service.

09 September 2021

The ultimate guide to REPROCELL’s stem cell research services

The ultimate guide to REPROCELL’s stem cell research services

Looking to outsource your stem cell research project? Discover everything you need to know in our ultimate guide to REPROCELL’s stem cell research services

16 August 2021

Will mRNA change medicine for good?

Will mRNA change medicine for good?

Find out if mRNA will change medicine for good. Read about the molecules rise to fame in 2020 and how it could be used to treat diseases such as cancer.

12 August 2021

Our top 10 stem cell culture products

Our top 10 stem cell culture products

Read our countdown of the op 10 stem cell culture products sold by REPROCELL as chosen by our customers.

02 July 2021

Human tissue testing and precision medicine

Human tissue testing and precision medicine

Find out how a recent nature article has sparked interest in the use of human tissue testing for precision medicine.

08 June 2021

The ultimate guide to Alvetex

The ultimate guide to Alvetex

Find out everything you need to know about Alvetex technology in our ultimate guide to Alvetex.

31 May 2021

How to bioengineer epithelial tissues in vitro

How to bioengineer epithelial tissues in vitro

Looking to bioengineer epithelial tissues in vitro? Find out how Alvetex can be used to create full-thickness epithelial tissues on the REPROCELL blog.

25 May 2021

Improving precision medicine strategies with human tissue testing

Improving precision medicine strategies with human tissue testing

Discover how you can improve your precision medicine strategies with human tissue testing.

29 April 2021

Precision medicine for the COVID-19 pandemic

Precision medicine for the COVID-19 pandemic

Learn how precision medicine could help to end the COVID-19 pandemic by accelerating the processes of understanding and treating disease.

03 February 2021

Protocol for immunocytochemistry of stem cells

Protocol for immunocytochemistry of stem cells

Read our tried-and-tested protocol for immunocytochemistry of stem cells and optimize your antibody concentrations.

29 January 2021

Five reasons to choose StemRNA 3rd Gen Reprogramming Technology

Five reasons to choose StemRNA 3rd Gen Reprogramming Technology

Looking for a more efficient iPSC reprogramming kit? Discover five reasons you should choose StemRNA 3rd Gen Reprogramming Technology for iPSC generation.

04 December 2020

What is Translational Science?

What is Translational Science?

Discover the definition of translational research and how it can improve drug discovery and development programs.

11 September 2020

This light-activated treatment could help patients with peripheral artery disease [Interview]

This light-activated treatment could help patients with peripheral artery disease [Interview]

Discover how this light-activated treatment could help patients with peripheral artery disease in this interview with the researchers.

01 September 2020

Four Examples of human models of respiratory diseases

Four Examples of human models of respiratory diseases

Looking for human models of respiratory diseases? Find 4 examples of translational respiratory disease models on the REPROCELL blog.

03 August 2020

Using 3D culture to improve Caco-2 permeability assays

Using 3D culture to improve Caco-2 permeability assays

Looking to elevate your permeability projects? Find out how you can use 3D culture to improve your Caco-2 permeability assays from REPROCELL.

14 July 2020

CRISPR-Cas9: Big Data, Precision Medicine and Universal Cell Therapy

CRISPR-Cas9: Big Data, Precision Medicine and Universal Cell Therapy

Find out how CRISPR-Cas9 can enhance big data, precision medicine, and universal cell therapy on the REPROCELL blog.

13 April 2020

How to Characterize the Barrier Properties of Alvetex®-Based Mucosal Models

How to Characterize the Barrier Properties of Alvetex®-Based Mucosal Models

Find out how to Characterize the Barrier Properties of your Alvetex®-Based Mucosal Models on the REPROCELL blog.

06 April 2020

How is Stemchymal® performing in Clinical Trials? [Infographic]

How is Stemchymal® performing in Clinical Trials? [Infographic]

Wondering how is Stemchymal® performing in Clinical Trials? Discover the main findings from Stemchymal's clinical trials in our infographic.

16 March 2020

Three challenges facing the introduction of iPSC-derived therapies

Three challenges facing the introduction of iPSC-derived therapies

Discover three of the main challenges facing the introduction of iPSC-derived therapies on the REPROCELL blog.

12 February 2020

Four ways stem cells can be used in medical treatments

Four ways stem cells can be used in medical treatments

Looking to find out how stem cells be used in medical treatments? Find 4 ways stem cells can be used therapeutically on the REPROCELL blog.

12 February 2020

Five Benefits of Precision Medicine

Five Benefits of Precision Medicine

Find out the top 5 benefits of precision medicine, to drug developers to patients, on the REPROCELL blog.

07 February 2020

Four reasons human tissues should be used to predict drug bioavailability

Four reasons human tissues should be used to predict drug bioavailability

Find out why human tissues should be used to predict drug bioavailability and permeability on the REPROCELL blog.

29 January 2020

How to estimate drug permeability using the Ussing Chamber technique

How to estimate drug permeability using the Ussing Chamber technique

Looking to estimate drug permeability using the Ussing Chamber technique? Find out how on the REPROCELL blog.

22 January 2020

Cost Effective, Lab-scale Spheroid Culture of iPSCs

Cost Effective, Lab-scale Spheroid Culture of iPSCs

Looking for cost effective, lab-scale, spheroid culture of iPSCs? Discover how the ABLE Bioreactor enables smarter cell production - no experience needed.

21 January 2020

4 TED Talks discussing the future of regenerative medicine

4 TED Talks discussing the future of regenerative medicine

Learn about the current limitations facing the future of regenerative medicine through these four TED Talks.

19 December 2019

Stem cells offer hope for sufferers of Spinocerebellar Ataxia

Stem cells offer hope for sufferers of Spinocerebellar Ataxia

Discover how stem cell treatments can offer hope for sufferers of Spinocerebellar Ataxia (SCA).

08 November 2019

How to mass culture induced pluripotent stem cells (iPSCs) using the ABLE Bioreactor System

How to mass culture induced pluripotent stem cells (iPSCs) using the ABLE Bioreactor System

Discover how to mass culture induced pluripotent stem cells (iPSCs) in spheroids using the ABLE Bioreactor System.

30 October 2019

What are the advantages of an internship to employers?

What are the advantages of an internship to employers?

Find out the advantages of an internship to employers on the REPROCELL blog. Discover how hiring an intern can benefit your company and employees.

23 October 2019

Which stem cell reprogramming technology should I use?

Which stem cell reprogramming technology should I use?

Wondering which stem cell reprogramming technology you should use for your iPSC project? Discover the pros and cons of RNA Reprogramming from REPROCELL.

17 October 2019

IBDiscovery: Combining patient and drug discovery data to transform healthcare

IBDiscovery: Combining patient and drug discovery data to transform healthcare

Learn how REPROCELL's IBDisocvery project is combining patient and drug discovery data to transform healthcare.

16 September 2019

Machine Learning and Big Data in Precision Medicine

Machine Learning and Big Data in Precision Medicine

Discover how machine learning and big data can be used in precision medicine to cut costs, reduce errors and gain faster drug approvals.

08 August 2019

Pluripotent Potential for Clinical Application

Pluripotent Potential for Clinical Application

Discover the potential of induced pluripotent stem cells (iPSCs) for clinical application on the REPROCELL blog.

25 July 2019

An Improved Model for IBD Drug Discovery

An Improved Model for IBD Drug Discovery

Looking to find an improved model for IBD drug discovery? Find out the benefits of human tissue testing on the REPROCELL blog.

11 July 2019

Advances in diagnostics, treatments, and frontiers of research in IBD

Advances in diagnostics, treatments, and frontiers of research in IBD

Find out the latest advances in diagnostics, treatments, and frontiers of research in IBD on the REPROCELL blog.

13 June 2019

How Human Organoculture can Improve Precision Medicine Strategies

How Human Organoculture can Improve Precision Medicine Strategies

Discover how human organoculture can be used to improve precision medicine strategies on the REPROCELL blog.

05 June 2019

Will The Microbiome Become The Next Hot Topic For Cancer Research?

Will The Microbiome Become The Next Hot Topic For Cancer Research?

Discover whether the microbiome will become the next hot topic for cancer research on the REPROCELL blog.

16 May 2019

REPROCELL Solutions for Respiratory Disease Researchers

REPROCELL Solutions for Respiratory Disease Researchers

Looking to outsource your respiratory disease research? Find out more about REPROCELL's solutions for respiratory disease researchers.

29 April 2019

Stem Cells for Autism

Stem Cells for Autism

Visit the REPROCELL blog and find out how stem cells could be used to treat autism in the future.

03 April 2019

Neurite Outgrowth Assays using StemRNA Neuro

Neurite Outgrowth Assays using StemRNA Neuro

Find out more about REPROCELL's neurite outgrowth assay that uses StemRNA Neuro cells.

20 March 2019

Using human iPSCs as an in vitro model for regenerative medicine and disease modelling

Using human iPSCs as an in vitro model for regenerative medicine and disease modelling

The conventional drug discovery pathway is a very inefficient process with the majority of candidate drugs not reaching the market due to safety and/or efficacy issues. But the use of iPSCs allows high throughput screening of therapies and disease-specific treatment using patient-specific models.

22 February 2019

The gut microbiome in health and disease: the future for diagnosis and treatment of IBD and IBS?

The gut microbiome in health and disease: the future for diagnosis and treatment of IBD and IBS?

Discover whether the gut microbiome, in health and disease, is the future for diagnosis and treatment of IBD and IBS on the REPROCELL blog.

12 February 2019

Tissue Sourcing for the Development of iPSC-derived Disease Models

Tissue Sourcing for the Development of iPSC-derived Disease Models

Looking to source primary tissues for iPSC generation? Find out more about tissue sourcing for the development of iPSC-derived disease models.

06 February 2019

REPROCELL Solutions for Gastrointestinal Researchers

REPROCELL Solutions for Gastrointestinal Researchers

Looking to outsource your gastrointestinal research? Find out more about REPROCELL's service solutions for gastrointestinal researchers.

25 October 2018

How animal testing is inaccurate and the alternatives

How animal testing is inaccurate and the alternatives

Find out how animal experimentation can lead to adverse drug effects on the REPROCELL blog.

25 May 2018

Human Tissue Testing in Drug Discovery and Development

Human Tissue Testing in Drug Discovery and Development

Discover how human tissue testing can be used in drug discovery and development to make the process smarter and more efficient.

27 March 2018

Xeno-free culture of stem cells in NutriStem® hPSC XF medium

Xeno-free culture of stem cells in NutriStem® hPSC XF medium

Find out more information about the xeno-free culture of stem cells using NutriStem® hPSC XF medium.

05 February 2018