Meet us next:   BIO International Convention 2025 – 4 September  ●  ELRIG – Drug Discovery in Scotland 2025 – 17 September  ●  The Cell & Gene Meeting on the Mesa 2025 – 6-8 October (in person) & 9-10 October (virtual)  ●  ELRIG – Drug Discovery – 21-22 October  ●  more on our events calendar
Prices for NutriStem, NutriCoat, and NutriFreez products will increase effective 1st August. Lock in the current price by getting your order by 31st July.

Stem Cell, Drug Discovery, and Analytical Services

Our services help stem cell and drug discovery scientists around the world advance their preclinical and clinical research.

Clinical Stem Cell Services

iPSC and MSC GMP master cell bank and clinical cell product manufacturing.

We provide end-to-end support for your cell therapy project, from sourcing clinically and commercially consented human tissues to GMP-compliant manufacturing. Using our proprietary non-integrating StemRNA™ Reprogramming Technology, we generate clinical iPSC Seed Clones that meet FDA, EMA, and PMDA standards. These clones can be expanded in a GMP environment to create Master Cell Banks (MCBs) for further cell therapy manufacturing. We provide GMP MCB services for iPSCs, iMSCs (iPSC-derived MSCs), and MSCs (also known as Mesenchymal Stem Cells, Mesenchymal Stromal Cells, or Medicinal Signalling Cells) at our GMP facility in Beltsville, USA, and through our European partner, Histocell.

Research Stem Cell Services

Footprint-free iPSC reprogramming and differentiation.

We have a complete portfolio of services for the reprogramming and differentiation of high-quality induced pluripotent stem cells (iPSCs). Our research stem cell services include donor recruitment, target cell isolation, iPSC reprogramming, expansion, characterization, neuronal differentiation, and gene editing. Using our proprietary RNA based technology, our services and products for stem cell scientists are used by leading pharmaceutical and biotechnology companies as well as top academic and government research institutions all around the world.

Gene Editing Services

With CRIPSR-SNIPER, the most efficient gene editing technique.

Through our collaboration with GenAhead Bio, we provide StemEdit – CRISPR-SNIPER clinical gene editing services. This novel approach to genome modification makes it possible to achieve otherwise challenging mutations such as the insertion of large gene fragments, biallelic mutations, and multiple gene knockouts – all with increased screening efficiency. CRISPR-SNIPER greatly increases the likelihood of project success. Our clinical gene editing service projects include bulk screening for optimal conditions, scheduled cloning, PCR confirmation of transfection and all required QC to ensure your clinically gene edited cells are suitable for cell therapy development.

Precision Medicine Services

Revolutionizing the way medicines are developed and selected for patients.

Our precision medicine services include our new Pharmacology-AI machine learning platform. Developed in collaboration with IBM and STFC, our automated system rapidly identifies the features driving variation in patient outcomes – streamlining the development of effective patient stratification strategies. Scientists and clinicians with clinical or genomic data can use Pharmacology-AI to identify the key features driving biomarker levels, drug response, or clinical outcome. Our experts can enable IBD researchers to analyze their data via our platform to identify the key ʻomicʼ or clinical features driving differences in drug or biomarker response. We are also developing applications for a number of other organ systems and therapeutic areas.

Preclinical and Drug Discovery CRO

Preclinical drug development using human fresh tissue testing.

Our GLP contract research services in human tissues have been trusted by the top pharma and biotech companies since 2002. We provide data that is highly predictive of in vivo drug responses by characterising drug safety, efficacy and absorption in human fresh tissues or bioengineered human tissues, de-risking later clinical trials. Through our extensive clinical networks in the USA and the UK, we have ready access to healthy and diseased human living tissues and organs. We also offer a range of assays in human bioengineered tissue models built on our Alvetex® platform, including models of IBD, skin and IPF, and can create custom assays for your drug discovery programs.

Preclinical and Drug Discovery CRO (overview)

Drug Discovery Assay Catalog

Clinical Laboratory Services

Comprehensive, personalized solutions for clinical research.

Our integrated network of central laboratories can support your clinical trial sample processing needs across three continents, from our accredited laboratories in the USA, UK, India, and Japan. Our GLP/GCLP and ISO compliant systems are operational 24/7. We offer a range of options including kit preparation, logistics, biospecimen processing and storage, biomarker discovery, and testing. We can coordinate, process, test, and analyze a range of fresh human biospecimens to meet the demands of your clinical research.

Human Tissue Samples

Quality biospecimens linked to detailed clinical and demographic data.

Our global biorepository of human tissue samples provides leading academic and industry researchers with access to over 600,000 human DNA, serum and tissue samples linked to detailed clinical and demographic data from 120,000 consented and anonymized patients on four continents. Customers of our human tissue samples and related molecular services include nearly every major pharmaceutical and biotechnology company, as well as top industry, academic, and government research institutions.

Genomic Services

Intensive customer service from assay design to data delivery.

We have more than two decades of experience in extracting nucleic acids from a wide variety of starting materials. We have a large capacity to isolate different nucleic acids from a range of biospecimens, including blood, solid tissues, swabs, and formalin-fixed paraffin embedded blocks. Our preclinical genomic services include DNA and RNA extraction, biomarker discovery and validation, real-time PCR, and next generation sequencing.

NEW in 2024: following expansion, Bioserve India (part of the REPROCELL Group) is now offering its oligonucleotide services worldwide.