REPROCELL’s Drug Discovery and Clinical Services

Research Stem Cell Services

• Overview
• Donor Recruitment and Patient-Derived Cells
• Target Cell Isolation
• iPSC Reprogramming Service
• iPSC Expansion, Characterization and Banking
• Neuronal Differentiation Services
• iPSC Genome Editing by CRISPR-SNIPER

Clinical Stem Cell Services

• GMP iPSC Master Cell Bank
• GMP-Grade iPSC Manufacturing
• Clinical iPSCs FAQ

Gene Editing Services

• CRISPR-SNIPER Gene Editing Service

Preclinical & Drug Discovery CRO

• Overview

• Drug Discovery Assay Catalog

• Human Tissue Assays
  • Inflammatory Bowel Disease
  • Skin Disease
  • Respiratory
  • ADME DMPK
  • Species Comparison
  • Genitourinary
  • Gastrointestinal Motility
  • Cardiovascular

• Platform Technologies
  • Tissue Baths and Wire Myographs
  • Ussing Chambers
  • Ex vivo Tissue Culture
  • Alvetex 3D Tissue Models

• Why Human Tissue?
  • The Use of Human Fresh Tissues in the Drug Discovery Pipeline
  • Drug Discovery Phases

Clinical Laboratory Services

• Overview

• Central Laboratory Services
  • Study Logistics
    • Kit Preparation & Shipment
    • Quality & Project Management
    • Biospecimen Storage
  • Biospecimen Processing
    • Whole Blood Processing
    • DNA & RNA Extraction
    • Cell Isolation & Enrichment
    • Primary Cell Derivation

Human Tissue Samples

• Overview
• Global Biorepository
• Biospecimen Partner Network
• Prospective Sample Collections
• FAQ – Biospecimens and Molecular Services

Genomic Services

• Overview
• DNA & RNA Extraction
• Real-Time PCR
• Biomarker Discovery & Validation
  • SNPlates™ – ready-made case control studies
• Next Generation Sequencing
  • What is Circulating Tumor DNA (ctDNA)?

Diagnostic Services

Therapeutic Pipeline

• Overview
• Q-cell GPR Cell Therapy
• Stemchymal MSC therapy