Genitourinary Assays
We offer an extensive range of assays in human genitourinary tissues including uterus, bladder, prostate, ureter and urethra. Our scientists can estimate the therapeutic efficacy of potential new therapies or assess the likelihood of off-target effects in these tissues.
Diagram of the organ bath model used for our Genitourinary studies.
Explore our Genitourinary Assays
Uterine Contractility
Alterations in uterine function can have significant consequences for human health, impacting conditions such as pregnancy and dysmenorrhea. We provide advanced uterine contractility assays using fresh, functional human uterine tissue to determine whether your test article induces contraction or relaxation of this critical organ.
Uterine Relaxation
We offer the unique capability to evaluate both uterine contraction and uterine relaxation in response to your test article. Understanding how compounds affect uterine relaxation is crucial for developing therapies targeting conditions such as preterm labor and dysmenorrhea, where excessive contractions must be controlled to ensure patient safety and comfort.
Bladder Contraction and Relaxation
One of our key areas of expertise is the assessment of smooth muscle contraction/ relaxation in fresh, functional human bladder tissues. We source bladder tissue multiple times a month, allowing us to evaluate the efficacy of your novel compounds in both normal and overactive bladder conditions.
Ureter Relaxation
The ureter is a structure that connects the kidneys to the bladder. It has a smooth muscle layer that propels urine to the bladder via peristalsis. Our organ bath system can be used to assess the effect of your test article on ureter relaxation (or contraction).
Urethra Contraction
The urethra plays a crucial role in the excretion of urine and semen. Any alterations in its structure or function, such as those caused by prostate hypertrophy, can significantly affect this process. We offer a comprehensive range of human-based services to evaluate the effects of your test compound on the contraction or relaxation of the human urethra.
