Unparallelled access to human biospecimens

The Bioserve global biorepository of human tissue samples is one of the largest commercial biorepositories in the world.

We have over 600,000 biospecimens collected on four different continents from various nationalities and ethnicities. The samples were collected from 120,000 unique donors under a strict Institutional Review Board (IRB).

All the samples in our global biorepository are anonymized with no link to the donor. Each sample has extensive demographic data including three generations of ethnicity and clinical information collected using a Case Report Form (CRF).

All the donors were consented, so that samples can be used for medical research, commercial research, and nucleic acid analysis, such as sequencing and expression analysis.

Each human tissue sample is accompanied with:

• Detailed demographic information, including family history for three generations
• Gold standard clinical diagnostic information
• Complete drug history, including adverse events
• Full pathology report, including H and E slides
• Complete phenotypic data

Samples consist of fresh frozen tumor and normal adjacent tissues, whole blood, serum, plasma, DNA, RNA and Formalin Fixed Paraffin Embedded (FFPE) blocks from both tumor and normal tissues and various diseases.

Fresh frozen tissues are stored in liquid nitrogen freezers in the vapor phase at −190° C; serum, plasma, and RNA are stored in −80°C freezers; DNAs are stored in −20°C; FFPE blocks are stored at room temperature.

Global biorepository

We have the human tissue samples you need — or we can procure them

If we donʼt already have a sample in our global biorepository that meets your exact requirements, we can source what you need. We have a growing network of partners with their own inventories of biospecimens. Plus, we can reach out for you beyond our network to establish even more procurement connections.

Biospecimen Partner Network

The procurement of high-quality, well-annotated, and properly consented biospecimens by the research community is complicated, cumbersome, and too often unsuccessful. Academic, government, and industry researchers often pursue fragmented search strategies ranging from inquiries to academic core facilities, to perusal of commercial vendor inventories, to establishing collaborations directly with health care practitioners for specimen access. Each of these approaches has limitations including limited specimen availability, prohibitive costs, or lack of access to appropriate collaborators.

The REPROCELL Bioserve partner network is a collaborative model that effectively reduces these complications. In addition to our global biorepositoryʼs inventory of many thousands of samples, our network has a vast and diverse range of human tissue samples. With our Partner Network we have created a single point of contact for the research community, providing unparalleled access to over 1.5 million biospecimens.

Custom Collections: Orphan Disease Network

Even with so many biospecimens available via our Bioserve Partner Network, we sometimes get requests for samples that we donʼt have on hand. In these situations, our custom prospective sample collections services can fulfil our clientsʼ needs. With our custom collections services, we can ask our our entire partner network to explore in multiple localities, so that we can quickly track down and obtain the specific samples you need. If theyʼre out there, we can find them.

• We are experts at new collection site recruitment, training, and monitoring.
• You can get back to your research.
• The job of procuring high quality tissue samples is in good hands.

In our prospective sample collections we can provide customized case report forms that specify the exact the types of sample data you need. We can also prepare your specimens according to your own protocols and requirements. We can provide short- to long-term specimen storage, either at REPROCELLʼs state-of-the-art banking facility or at the sample collection site. And, when you are ready to have them sent to you, we can ship your custom biospecimens directly from the storage location on the same day.