Scientific Publications
Recent Publications by REPROCELL Scientists
Genomics & molecular services
Mutational landscape of BRCA gene mutations in Indian breast cancer patients: retrospective insights from a diagnostic lab
Rosy Chikkala, Deepak Bhayal, Nikki Rani, Rama Modali, Kishor Bhatia & Bhawna Dubey
Egyptian Journal of Medical Human Genetics, 5 September 2024
DOI: 10.1186/s43042-024-00567-6
Alvetex
Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites
Kirsty Goncalves, Stefan Przyborski
Neural Regeneration Research, 29 July 2024
DOI: 10.4103/NRR.NRR-D-23-01628
Alvetex
Cell Senescence-Independent Changes of Human Skin Fibroblasts with Age
Nicola Fullard, James Wordsworth, Ciaran Welsh, Victoria Maltman, Charlie Bascom, Ryan Tasseff, Robert Isfort, Lydia Costello, Rebekah-Louise Scanlan, Stefan Przyborski, and Daryl Shanley
Cells, 9 April 2024
DOI: 10.3390/cells13080659
iPSCs
Characterization of human iPSC-derived sensory neurons and their functional assessment using multi electrode array
Minami Hiranuma, Yuichi Okuda, Yuuka Fujii, Jean-Philippe Richard & Tomohisa Watanabe
Scientific Reports, 12 March 2024
DOI: 10.1038/s41598-024-55602-8
Alvetex
An in vitro model to study immune activation, epithelial disruption and stromal remodelling in inflammatory bowel disease and fistulising Crohn’s disease
Claire L. Mobbs, Nicole J. Darling and Stefan Przyborski
Frontiers in Immunology, 12 February 2024
DOI: 10.3389/fimmu.2024.1357690
ec23
Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23
Arto Määttä, Rebecca Nixon, Neil Robinson, Carrie A Ambler, Kirsty Goncalves, Victoria Maltman, Stefan Przyborski
J Cosmet Dermatol, 03 January 2023
DOI: 10.1111/jocd.15629
Alvetex
Development of a mammalian neurosensory full-thickness skin equivalent and its application to screen sensitizing stimuli
Freer M, Darling N, Goncalves K, Mills KJ, Przyborski S.
Bioeng Transl Med, January 2023
DOI: 10.1002/btm2.10484
Alvetex
Application of biomimetic surfaces and 3D culture technology to study the role of extracellular matrix interactions in neurite outgrowth and inhibition
K.E.Goncalves, S.Phillips, D.S.H.Shah, D.Athey, S.A.Przyborski
Biomaterials Advances, 23 November 2022
DOI: 10.1016/j.bioadv.2022.213204
Alvetex
Investigation into the effect of skin tone modulators and exogenous stress on skin pigmentation utilizing a novel bioengineered skin equivalent
Kirsty Goncalves, Paola De Los Santos Gomez, Lydia Costello, Lucy Smith, Hugh Mead, Amy Simpson, Stefan Przyborski
Bioengineering and Translational Medicine, 26 September 2022
DOI: 10.1002/btm2.10415
Alvetex
Recreating Tissue Structures Representative of Teratomas In Vitro Using a Combination of 3D Cell Culture Technology and Human Embryonic Stem Cells
Alejandro Hidalgo Aguilar, Lucy Smith, Dominic Owens, Rebecca Quelch, and Stefan Przyborski
Bioengineering 2022, 9(5), 185, 22 April 2022
DOI: 10.3390/bioengineering9050185
iPSCs
Clinically compatible advances in blood-derived endothelial progenitor cell isolation and reprogramming for translational applications
Sarah Eminli, Baraa Kwieder, Kevin Yi, Christopher JZ Huang, Jung-Il Moon, C-Hong Chang, Fedir N Kiskin, Nicholas W Morrell, Brad Hamilton, Amer A Rana
New Biotechnology, 25 July 2021
DOI: 10.1016/j.nbt.2021.02.001
Alvetex
Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts
L A Smith, A Hidalgo Aguilar, D D G Owens, R H Quelch, E Knight and S A Przyborski
Frontiers in Cell Development and Biology, 06 May 2021
DOI: 10.3389/fcell.2021.667246
Alvetex
Use of Porous Polystyrene Scaffolds to Bioengineer Human Epithelial Tissues In Vitro
Costello L, Darling N, Freer M, Bradbury S, Mobbs C, Przyborski S
Methods in Molecular Biology (Clifton, N.J.), 1 January 2021
DOI: 10.1007/978-1-0716-1246-0_20
iPSCs
Protocol: Generation of Human iPSCs by Reprogramming with the Unmodified Synthetic mRNA
Robert R Annand, 24 November 2020
Part of the book series: Methods in Molecular Biology (MIMB), volume 2239
Alvetex
Bioengineering Novel in vitro Co-culture Models That Represent the Human Intestinal Mucosa With Improved Caco-2 Structure and Barrier Function
Nicole J Darling, Claire L Mobbs, Ariana L González-Hau, Matthew Freer and Stefan Przyborski
Frontiers in Bioengineering and Biotechnology, 31 August 2020
DOI: 10.3389/fbioe.2020.00992
Alvetex
Applications of novel bioreactor technology to enhance the viability and function of cultured cells and tissues
H W Hoyle, L A Smith, R J Williams and S A Przyborski
The Royal Society — Interface Focus, 14 February 2020
DOI: 10.1098/rsfs.2019.0090
Alvetex
Dataset supporting “Multiple scattering in scanning helium microscopy”
Lambrick S, Vozdecky L, Bergin M, Halpin J E, MacLaren D A, Dastoor P C, Przyborski S A, et al.
University of Cambridge, Apollo Repository, 31 January 2020
DOI: 10.17863/CAM.48316
iPSCs
Comparative study between lactose-silk fibroin conjugates and extracellular matrices as a substrate for the culture of human induced pluripotent stem cell-derived hepatocytes
Yohkoa Gotoh, Shigob Niimi, Kenichic Tamura, Rinac Akahira, Mitsuruc Inamura
Bio-Medical Materials and Engineering, 12 May 2020
DOI: 10.3233/BME-201078
iPSCs
Wnt inhibition facilitates RNA-mediated reprogramming of human somatic cells to naive pluripotency
Nicholas Bredenkamp, Jian Yang, James Clarke, Giuliano Giuseppe Stirparo, Ferdinand von Meyenn, Sabine Dietmann, Duncan Baker, Rosalind Drummond, Yongming Ren, Dongwei Li, Chuman Wu, Maria Rostovskaya, Sarah Eminli-Meissner, Austin Smith, Ge Guo
Stem Cell Reports, 10 December 2019
DOI: 10.1016/j.stemcr.2019.10.009
Alvetex
Engineering a Multilayered Skin Equivalent: The Importance of Endogenous Extracellular Matrix Maturation to Provide Robustness and Reproducibility
Lydia Costello, Nicola Fullard, Mathilde Roger, Steven Bradbury, Teresa Dicolandrea, Robert Isfort, Charles Bascom, Stefan Przyborski
Skin Tissue Engineering, 31 May 2019
DOI: 10.1007/978-1-4939-9473-1_9
iPSCs
Generation of safe and therapeutically effective human induced pluripotent stem cell‐derived hepatocyte‐like cells for regenerative medicine
Kazuo Takayama, Naoki Akita, Natsumi Mimura, Rina Akahira, Yukimasa Taniguchi, Makoto Ikeda, Fuminori Sakurai, Osamu Ohara, Tomohiro Morio, Kiyotoshi Sekiguchi, and Hiroyuki Mizuguchi
Hepatology Communications, 21 October 2017
DOI: 10.1002/hep4.1111
iPSCs
Efficient reprogramming of human fibroblasts and blood-derived endothelial progenitor cells using nonmodified RNA for reprogramming and immune evasion
Poleganov MA, Eminli S, Beissert T, Herz S, Moon J-I, Goldmann J, Beyer A, Heck R, Burkhart I, Roldan DB, Tureci O, Yi K, Hamilton B, Sahin U.
Human Gene Therapy, 27 August 2015
DOI: 10.1089/hum.2015.045
