REPROCELL Publications

Recent Publications by REPROCELL Scientists

Alvetex

Cell Senescence-Independent Changes of Human Skin Fibroblasts with Age
Nicola Fullard, James Wordsworth, Ciaran Welsh, Victoria Maltman, Charlie Bascom, Ryan Tasseff, Robert Isfort, Lydia Costello, Rebekah-Louise Scanlan, Stefan Przyborski, and Daryl Shanley

Cells
9 April 2024
DOI: 10.3390/cells13080659

iPSCs

Characterization of human iPSC-derived sensory neurons and their functional assessment using multi electrode array
Minami Hiranuma, Yuichi Okuda, Yuuka Fujii, Jean-Philippe Richard & Tomohisa Watanabe

Scientific Reports
12 March 2024
DOI: 10.1038/s41598-024-55602-8

Alvetex

An in vitro model to study immune activation, epithelial disruption and stromal remodelling in inflammatory bowel disease and fistulising Crohn’s disease
Claire L. Mobbs, Nicole J. Darling and Stefan Przyborski

Frontiers in Immunology
12 February 2024
DOI: 10.3389/fimmu.2024.1357690

ec23

Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23
Arto Määttä, Rebecca Nixon, Neil Robinson, Carrie A Ambler, Kirsty Goncalves, Victoria Maltman, Stefan Przyborski

J Cosmet Dermatol
03 January 2023
DOI: 10.1111/jocd.15629

Alvetex

Development of a mammalian neurosensory full-thickness skin equivalent and its application to screen sensitizing stimuli
Freer M, Darling N, Goncalves K, Mills KJ, Przyborski S.

Bioeng Transl Med
January 2023
DOI: 10.1002/btm2.10484

Alvetex

Application of biomimetic surfaces and 3D culture technology to study the role of extracellular matrix interactions in neurite outgrowth and inhibition
K.E.Goncalves, S.Phillips, D.S.H.Shah, D.Athey, S.A.Przyborski

Biomaterials Advances
23 November 2022
DOI: 10.1016/j.bioadv.2022.213204

Alvetex

Investigation into the effect of skin tone modulators and exogenous stress on skin pigmentation utilizing a novel bioengineered skin equivalent
Kirsty Goncalves, Paola De Los Santos Gomez, Lydia Costello, Lucy Smith, Hugh Mead, Amy Simpson, Stefan Przyborski

Bioengineering and Translational Medicine
26 September 2022
DOI: 10.1002/btm2.10415

Alvetex

Recreating Tissue Structures Representative of Teratomas In Vitro Using a Combination of 3D Cell Culture Technology and Human Embryonic Stem Cells
Alejandro Hidalgo Aguilar, Lucy Smith, Dominic Owens, Rebecca Quelch, and Stefan Przyborski

Bioengineering 2022, 9(5), 185
22 April 2022
DOI: 10.3390/bioengineering9050185

iPSCs

Clinically compatible advances in blood-derived endothelial progenitor cell isolation and reprogramming for translational applications
Sarah Eminli, Baraa Kwieder, Kevin Yi, Christopher JZ Huang, Jung-Il Moon, C-Hong Chang, Fedir N Kiskin, Nicholas W Morrell, Brad Hamilton, Amer A Rana

New Biotechnology
25 July 2021
DOI: 10.1016/j.nbt.2021.02.001

Alvetex

Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts
L A Smith, A Hidalgo Aguilar, D D G Owens, R H Quelch, E Knight and S A Przyborski

Frontiers in Cell Development and Biology
06 May 2021
DOI: 10.3389/fcell.2021.667246

Alvetex

Use of Porous Polystyrene Scaffolds to Bioengineer Human Epithelial Tissues In Vitro
Costello L, Darling N, Freer M, Bradbury S, Mobbs C, Przyborski S

Methods in Molecular Biology (Clifton, N.J.)
1 January 2021
DOI: 10.1007/978-1-0716-1246-0_20

iPSCs

Protocol: Generation of Human iPSCs by Reprogramming with the Unmodified Synthetic mRNA
Robert R Annand, 24 November 2020

Part of the book series: Methods in Molecular Biology (MIMB), volume 2239

Alvetex

Bioengineering Novel in vitro Co-culture Models That Represent the Human Intestinal Mucosa With Improved Caco-2 Structure and Barrier Function
Nicole J Darling, Claire L Mobbs, Ariana L González-Hau, Matthew Freer and Stefan Przyborski

Frontiers in Bioengineering and Biotechnology
31 August 2020
DOI: 10.3389/fbioe.2020.00992

Alvetex

Applications of novel bioreactor technology to enhance the viability and function of cultured cells and tissues
H W Hoyle, L A Smith, R J Williams and S A Przyborski

The Royal Society — Interface Focus
14 February 2020
DOI: 10.1098/rsfs.2019.0090

Alvetex

Dataset supporting “Multiple scattering in scanning helium microscopy”
Lambrick S, Vozdecky L, Bergin M, Halpin J E, MacLaren D A, Dastoor P C, Przyborski S A, et al.

University of Cambridge, Apollo Repository
31 January 2020
DOI: 10.17863/CAM.48316

iPSCs

Comparative study between lactose-silk fibroin conjugates and extracellular matrices as a substrate for the culture of human induced pluripotent stem cell-derived hepatocytes
Yohkoa Gotoh, Shigob Niimi, Kenichic Tamura, Rinac Akahira, Mitsuruc Inamura

Bio-Medical Materials and Engineering
12 May 2020
DOI: 10.3233/BME-201078

iPSCs

Wnt inhibition facilitates RNA-mediated reprogramming of human somatic cells to naive pluripotency
Nicholas Bredenkamp, Jian Yang, James Clarke, Giuliano Giuseppe Stirparo, Ferdinand von Meyenn, Sabine Dietmann, Duncan Baker, Rosalind Drummond, Yongming Ren, Dongwei Li, Chuman Wu, Maria Rostovskaya, Sarah Eminli-Meissner, Austin Smith, Ge Guo

Stem Cell Reports
10 December 2019
DOI: 10.1016/j.stemcr.2019.10.009 

Alvetex

Engineering a Multilayered Skin Equivalent: The Importance of Endogenous Extracellular Matrix Maturation to Provide Robustness and Reproducibility
Lydia Costello, Nicola Fullard, Mathilde Roger, Steven Bradbury, Teresa Dicolandrea, Robert Isfort, Charles Bascom, Stefan Przyborski

Skin Tissue Engineering
31 May 2019
DOI: 10.1007/978-1-4939-9473-1_9

iPSCs

Generation of safe and therapeutically effective human induced pluripotent stem cell‐derived hepatocyte‐like cells for regenerative medicine
Kazuo Takayama, Naoki Akita, Natsumi Mimura, Rina Akahira, Yukimasa Taniguchi, Makoto Ikeda, Fuminori Sakurai, Osamu Ohara, Tomohiro Morio, Kiyotoshi Sekiguchi, and Hiroyuki Mizuguchi

Hepatology Communications
21 October 2017
DOI: 10.1002/hep4.1111 

iPSCs

Efficient reprogramming of human fibroblasts and blood-derived endothelial progenitor cells using nonmodified RNA for reprogramming and immune evasion
Poleganov MA, Eminli S, Beissert T, Herz S, Moon J-I, Goldmann J, Beyer A, Heck R, Burkhart I, Roldan DB, Tureci O, Yi K, Hamilton B, Sahin U.

Human Gene Therapy
27 August 2015
DOI: 10.1089/hum.2015.045