
How Biomarkers Are Shaping the Future of Skin Disease Treatment
04 February 2025
Discover how biomarkers are revolutionizing the treatment of skin diseases by enabling more precise and effective therapies.

Redefining Success in IBD Drug Discovery with Human Tissue Models
11 December 2024
Redefining IBD drug discovery with a dual-pronged approach through human bioengineered and fresh tissue.

Key Strategies Central Labs Use to Fast-Track Time to Market
18 November 2024
Learn how central labs use automation, outsourcing, and AI to accelerate drug development, reduce costs, and improve clinical trial accuracy and efficiency.

REPROCELL's Advanced Skin Tissue Engineering
31 October 2024
Discover REPROCELL's pioneering 3D skin tissue engineering, enhancing drug development and skincare research with accurate and robust human skin models.

From Fibroblasts to Cancer-Attacking Cells: Insights from Recent Research on Natural Killer Cells Derived from Clinical Grade iPSCs
16 October 2024
Discover the differentiation potential of induced pluripotent stem cells (iPSC) to cytotoxic NK cells, including recent advancements in research and therapy.

The Power of Human Tissue Models in Preclinical Research
03 October 2024
Discover how human tissue models are transforming drug safety assessments and improving outcomes in preclinical research through real-world case studies.

Understanding Safety Pharmacology in Human Tissues
26 August 2024
Explore the role of safety pharmacology in drug discovery, and the importance of human tissue studies for predicting and mitigating potential effects.

Breaking Ground in Alzheimer’s Research: A New Path to Drug Discovery and Personalized Medicine
22 August 2024
Breaking new ground in Alzheimer's research, a study by Durham University uncovers potential therapeutic targets using advanced stem cell technology.

AI in Drug Discovery: The Role of SHAP in Pharmacology
11 July 2024
Learn how Explainable AI, like SHAP, is transforming drug discovery by providing transparency and clarity in machine learning models.

Harnessing Functional Genomics to Revolutionize Inflammatory Bowel Disease Treatment
07 June 2024
Discover how functional genomics is transforming IBD treatment with groundbreaking research on ETS2's role in inflammation.

Leveraging Human Tissue Models with Preclinical and Drug Discovery CRO
05 April 2024
Our Preclinical and Drug Discovery CRO is transforming the landscape of drug development with new technologies and ethically sourced human tissue models.

Data Privacy and Protection in AI for Precision Medicine
31 October 2023
Discover how AI is revolutionizing data protection and security in precision medicine.

Bias in AI for precision medicine
02 October 2023
Without proper and due consideration in the design and delivery of new therapies and diagnostics, there is a risk that biased datasets will skew outcomes towards certain groups.

Why do patients respond differently to drugs? AI may provide an answer
05 May 2023
Learn how artificial intelligence combined with human tissue testing could help us understand why patients respond to drugs differently.

Wire myography: the ultimate guide (protocol included)
25 April 2023
Learn how to measure the reactivity and functional response of arteries in the wire myograph system in our wire myograph protocol.

Alternative testing methods covered by the FDA Modernization Act 2.0
06 March 2023
Discover whether the FDA Modernization Act 2.0. will increase the use of non-animal, alternative testing methods in drug development.

Everything you need to know about the motilin receptor
21 February 2023
Explore the function, physiology, & pharmacology of the motilin receptor. Discover what models can be used to investigate motilin mimetics preclinically.

Make a Difference with Fresh Residual Human Tissue Donation for Research – How to Get Involved!
31 January 2023
Discover the importance of fresh human tissue to healthcare development. Explore some of the options to donate residual tissue to pharmaceutical research.

Clinical Trials: An Evolutionary Perspective
18 January 2023
Find out how clinical trial systems and processes have developed and evolved during human history.

From rat aorta to resistance arteries: measuring vascular contractility
16 January 2023
Explore how isolated blood vessels can be used to determine drug behavior and discover translational alternatives to measuring vascular tone in rat aorta.

Everything we know about resistance arteries
21 November 2022
Learn about the physiology of resistance arteries in health and disease. Discover why they are important for controlling blood flow to vital organs.

4 ways ex vivo models offer Pharma better alternatives to animal testing
01 November 2022
Learn more about ex vivo models, and how these under-appreciated systems are helping Pharma reduce animal testing.

How to isolate PBMCs from whole blood using density gradient centrifugation
19 October 2022
Find out how to isolate PBMCs from whole blood samples using density gradient centrifugation a.k.a. the Ficoll Overlay method.

Everything we know about the human relaxin peptide family
28 September 2022
Discover the physiology and pharmacology of the human relaxin peptide family and their analogs. Learn about the role of human tissue in ex vivo research.

Endogenous and exogenous affectors of uterine contractility
27 September 2022
Discover everything you need to know about ex vivo uterine contractility models. Learn about the use of uterine tissue in drug development and research.

How human fresh tissue models are helping RCD405 achieve regulatory approval
17 August 2022
Discover how Arcede Pharma recently used human tissue testing to generate preclinical efficacy data for their compound RCD405.

What are PBMCs? Everything you need to know about Peripheral Blood Mononuclear Cells
10 August 2022
PBMC is short for Peripheral Blood Mononuclear Cell, or any blood cell with a single nucleus. Many of our immune cells are PBMCs, including lymphocytes.

Protocol for buffy coat preparation from whole blood
09 August 2022
Read our simple, three-step protocol for buffy coat preparation from whole blood. Learn how you can isolate the buffy-coat from whole blood samples.

Protocol for PBMC isolation from buffy coat samples
09 August 2022
Learn how to isolate Peripheral Blood Mononuclear Cells (PBMCs) from buffy coat samples. Discover a protocol for the isolation and counting of PBMCs.

Ultimate guide to nonanimal cardiovascular safety pharmacology
03 August 2022
Discover examples of receptors that are flagged during receptor binding studies and which can then be explored through functional assays.

Everything you need to know about the 5-HT2B receptor
01 July 2022
Explore the key physiological and pharmacological features of the 5-HT2B receptor plus its long and complicated relationship with cardiotoxicity.

Limitations of the isolated perfused heart and alternative models
24 May 2022
Discover the various limitations of the isolated perfused heart model, and human, ex vivo alternatives you can incorporate into your research instead.

Everything we know about the 5-HT2A (serotonin) receptor
04 May 2022
Read our ultimate guide to the 5-HT2A serotonin receptor. Discover the pharmacology and physiology of 5-HT2A in the nervous and cardiovascular systems.

Everything we know about the 5-HT1B receptor
21 April 2022
Discover everything scientists know, so far, about the pharmacology, molecular structure, and function of the human 5HT1B and 5HT1D receptor.

Skin biopsy and ex vivo culture methods
29 March 2022
Looking for skin biopsy and ex vivo culture methods to use in your research? Discover a range of ex vivo and in vitro skin models outlined in this article.

The influence of the microbiome on inflammatory bowel disease
18 March 2022
Learn about the the influence of the gut microbiome on inflammatory bowel disease (IBD) and how precision medicine may change the way we treat IBD.

What is Human Tissue Testing?
14 March 2022
Discover the definition of human tissue testing and how it can enhance your drug discovery research on the REPROCELL blog.

REPROCELL Solutions for Skin Disease Researchers
04 March 2022
Looking to outsource your skin disease research? Discover REPROCELL's range of solutions for skin disease researchers today.
![Predicting Psoriasis Drug Efficacy in Human Skin [INFOGRAPHIC]](https://www.reprocell.com/hs-fs/hubfs/07AUG20%20human%20skin%20microscopy%20histology%20cross%20section-1.jpeg?width=756&height=425&name=07AUG20%20human%20skin%20microscopy%20histology%20cross%20section-1.jpeg)
Predicting Psoriasis Drug Efficacy in Human Skin [INFOGRAPHIC]
03 March 2022
View our infographic and discover how REPROCELL scientists helped Pharma to predicting psoriasis drug efficacy in human skin biopsies.

Inserts or plates for your 3D cell culture?
28 February 2022
Struggling to decide between inserts or plates for your 3D cell culture? Visit our blog and discover how to choose the best 3D system for your research.

How to improve your 3D Cell Culture using Small-scale Perfusion Systems
15 February 2022
Discover how to improve your 3D cell culture using small-scale perfusion systems on the REPROCELL blog.

Enhance your epithelial barriers assay using Alvetex®
07 February 2022
Looking to improve the translatability of your epithelial models? Find out how to enhance your epithelial barriers assay using Alvetex.

How we established an in vitro Parkinson’s Disease model
24 November 2021
Discover how to establish an in vitro Parkinson’s Disease model using iPSC-derived neurons - from patient screening to neuronal maturation.

Human tissue testing and precision medicine
08 June 2021
Find out how a recent nature article has sparked interest in the use of human tissue testing for precision medicine.

The ultimate guide to Alvetex
31 May 2021
Find out everything you need to know about Alvetex technology in our ultimate guide to Alvetex.

How to bioengineer epithelial tissues in vitro
25 May 2021
Looking to bioengineer epithelial tissues in vitro? Find out how Alvetex can be used to create full-thickness epithelial tissues on the REPROCELL blog.

Precision medicine for the COVID-19 pandemic
03 February 2021
Learn how precision medicine could help to end the COVID-19 pandemic by accelerating the processes of understanding and treating disease.

What is Translational Science?
11 September 2020
Discover the definition of translational research and how it can improve drug discovery and development programs.
![This light-activated treatment could help patients with peripheral artery disease [INTERVIEW]](https://www.reprocell.com/hs-fs/hubfs/07AUG20%20heart%20disease%20blockage%20blood%20vessel%20fat%20deposit.jpeg?width=756&height=425&name=07AUG20%20heart%20disease%20blockage%20blood%20vessel%20fat%20deposit.jpeg)
This light-activated treatment could help patients with peripheral artery disease [INTERVIEW]
01 September 2020
Discover how this light-activated treatment could help patients with peripheral artery disease in this interview with the researchers.

4 Examples of human models of respiratory diseases
03 August 2020
Looking for human models of respiratory diseases? Find 4 examples of translational respiratory disease models on the REPROCELL blog.

Using 3D culture to improve Caco-2 permeability assays
14 July 2020
Looking to elevate your permeability projects? Find out how you can use 3D culture to improve your Caco-2 permeability assays from REPROCELL.

How to Characterize the Barrier Properties of Alvetex®-Based Mucosal Models
06 April 2020
Find out how to Characterize the Barrier Properties of your Alvetex®-Based Mucosal Models on the REPROCELL blog.

4 reasons human tissues should be used to predict drug bioavailability
29 January 2020
Find out why human tissues should be used to predict drug bioavailability and permeability on the REPROCELL blog.

How to estimate drug permeability using the Ussing Chamber technique
22 January 2020
Looking to estimate drug permeability using the Ussing Chamber technique? Find out how on the REPROCELL blog.

IBDiscovery: Combining patient and drug discovery data to transform healthcare
16 September 2019
Learn how REPROCELL's IBDisocvery project is combining patient and drug discovery data to transform healthcare.

An Improved Model for IBD Drug Discovery
11 July 2019
Looking to find an improved model for IBD drug discovery? Find out the benefits of human tissue testing on the REPROCELL blog.

Advances in diagnostics, treatments, and frontiers of research in IBD
13 June 2019
Find out the latest advances in diagnostics, treatments, and frontiers of research in IBD on the REPROCELL blog.

How Human Organoculture can Improve Precision Medicine Strategies
05 June 2019
Discover how human organoculture can be used to improve precision medicine strategies on the REPROCELL blog.

Will The Microbiome Become The Next Hot Topic For Cancer Research?
16 May 2019
Discover whether the microbiome will become the next hot topic for cancer research on the REPROCELL blog.

REPROCELL Solutions for Respiratory Disease Researchers
29 April 2019
Looking to outsource your respiratory disease research? Find out more about REPROCELL's solutions for respiratory disease researchers.

Using human iPSCs as an in vitro model for regenerative medicine and disease modelling
22 February 2019
The conventional drug discovery pathway is a very inefficient process with the majority of candidate drugs not reaching the market due to safety and/or efficacy issues. But the use of iPSCs allows high throughput screening of therapies and disease-specific treatment using patient-specific models.

The gut microbiome in health and disease: the future for diagnosis and treatment of IBD and IBS?
12 February 2019
Discover whether the gut microbiome, in health and disease, is the future for diagnosis and treatment of IBD and IBS on the REPROCELL blog.

REPROCELL Solutions for Gastrointestinal Researchers
25 October 2018
Looking to outsource your gastrointestinal research? Find out more about REPROCELL's service solutions for gastrointestinal researchers.

How animal testing is inaccurate and the alternatives
25 May 2018
Find out how animal experimentation can lead to adverse drug effects on the REPROCELL blog.

Human Tissue Testing in Drug Discovery and Development
27 March 2018
Discover how human tissue testing can be used in drug discovery and development to make the process smarter and more efficient.