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Bioreactor Systems for Scalable iPSC and 3D Cell Culture


Move beyond 2D culture with bioreactor systems designed for reproducible, scalable 3D models and stem cell workflows. 

As drug discovery, stem cell research, and cell therapy development advance, researchers are increasingly adopting 3D culture systems, including spheroids, organoids, and iPSC-derived models, to generate data that better reflects human biology.

REPROCELL provides a portfolio of bioreactor solutions that support the transition from traditional culture methods to scalable, controlled and reproducible 3D workflows.

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ABLE® Bioreactor Systems

The ABLE 3D Magnetic Stir and Disposable Bioreactor System provides a low-shear, uniform-agitation culture environment optimized for suspension cultivation of stem cells. The 30 mL bioreactor vessel is designed with delta-shaped impellers and a conical shaft, offering ideal spheroid forming culture conditions for iPS cell cultivation and subsequent differentiation in the same flask.

able-500-ml-disposable-bioreactor-p297-201_medium

BioThrust™ Bioreactor Systems

Designed and manufactured by BioThrust GmbH (Germany). The ComfyCell bioreactors are a revolutionary approach to scalable CGT manufacturing, leveraging the proprietary Membrane Stirrer to increase gas transfer 10-fold while reducing shear forces to a minimum and eliminating all foaming, even at commercial volumes of up to 200L.

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2mag Stirrer Systems

bioMIXdrive – stirring drives for cell cultures: designed for careful and protective mixing of cell suspensions and culture broths, developed for highest demands as well as warming-free and uncompromising continuous operations for e.g. in CO2-incubators.

bioMIXcontrol – external control units: designed for bioMIXdrive stirring drives.

2mag bioMIXdrive 1 with bioMIXcontrol

 


Supporting the Transition from 2D Culture to Scalable 3D Models

Researchers are increasingly adopting 3D culture systems, including spheroids, organoids, and induced pluripotent stem cell (iPSC)-derived models, to generate data that better reflects human biology. Bioreactor systems provide the controlled culture environments needed to support these advanced models, improving nutrient delivery, oxygen transfer, and overall culture consistency compared to traditional static methods. This enables the development of more physiologically relevant in vitro models while reducing experimental variability.

Whether you are transitioning from 2D to 3D culture, expanding sensitive stem cell populations, or scaling established workflows, REPROCELL offers bioreactor solutions designed to support every stage of your research. By combining controlled culture conditions, low-shear environments, and scalable platform options, our bioreactor portfolio helps researchers achieve reproducible results and confidently advance from early feasibility studies to more complex and translational applications.


Request a demo (UK & Europe only)