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Small Molecules

Stemgent™ Stemolecule™ by REPROCELL®


Listed by Product Name

hES Cell Cloning & Recovery Supplement (01-0014-500)
Stemgent hES Cell Cloning & Recover Supplement is a 1000× concentrate of Thiazovivin (2mM). In culture media it significantly improves the likelihood of primaryful sub-cloning from single cells, and increases attachment after passaging. This supplement is a ROCK inhibitor (see Thiazovivin, cat. # 04-0017 for more information).
More information →
01-0014-500 5 × 100 µL

USA Store UK/Europe Store

A83-01 (04-0014) 
A83-01 is a selective inhibitor of the transforming growth factor-beta (TGF-β) type I receptor ALK5, the Activin/Nodal receptor ALK4, and the nodal receptor ALK71.
More information →
04-0014 2 mg
04-0014-10 10 mg
USA Store UK/Europe Store
ALK5 Inhibitor (RepSox) (04-0015)
ALK5 Inhibitor (also known as RepSox, E 616452, and SJN 2511) is a selective and ATP-competitive inhibitor of the TGF-β family type I receptor of activin receptor-like kinase (ALK5).
More information →
04-0015 1 mg
USA Store UK/Europe Store
All-Trans Retinoic Acid (04-0021)
All-Trans Retinoic Acid (ATRA) is the oxidized form of Vitamin A, functioning as a signaling molecule for various developmental pathways that control differentiation and proliferation.
More information →
04-0021 100 mg
USA Store UK/Europe Store
CHIR99021 (04-0004)
CHIR99021 is a highly potent, specific and effective inhibitor of glycogen synthase kinase 3 beta (GSK-3β).
More information →
04-0004 2 mg
04-0004-10 10 mg
04-0004-02 2 mg (10 mM)
USA Store UK/Europe Store
Cyclopamine (04-0022)
Cyclopamine is a steroid alkaloid isolated from the corn lily (Veratrum californicum) that is a Smoothened antagonist involved in both embryogenesis and cancer progression.
More information →
04-0022 2 mg
USA Store UK/Europe Store
DAPT (04-0041)
DAPT (a.k.a. GSI-IX or LY-374973) is a cell-permeable dipeptide that inhibits γ-secretase and indirectly inhibits Notch, a γ-secretase substrate.
More information →
04-0041 5 mg
USA Store UK/Europe Store
Dorsomorphin (04-0024)
Dorsomorphin dihydrochloride (a.k.a. Compound C) is a potent inhibitor of AMP-activated protein kinase (AMPK) and bone morphogenic protein (BMP) signaling.
More information →
04-0024 2 mg
USA Store UK/Europe Store
Doxycycline hyclate (04-0016)
Doxycycline hyclate (dox) is a broad spectrum antibiotic derivative of tetracycline and an inhibitor of matrix metalloproteinases.
More information →
04-0016 10 mg
USA Store UK/Europe Store
ec23 (SRP002)
A light-stable pan-RAR receptor agonist that maintains the same biological activity as ATRA (all-trans retinoic acid).
More information →
SRP002 5 mg
SRP002-2 2 × 5 mg
USA Store UK/Europe Store
Forskolin (04-0025)
Forskolin is a natural product adenylate cyclase activator that increases cyclic AMP levels.
More information →
04-0025 2 mg
USA Store UK/Europe Store
KAAD-Cyclopamine (04-0028)
KAAD-cyclopamine is a sonic hedgehog antagonist that targets Smoothened, a 7-transmembrane receptor of the hedgehog signaling pathway.
More information →
04-0028 100 µg
USA Store UK/Europe Store
LDN-193189 (04-0074)
LDN193189 is a cell permeable, small molecule inhibitor of bone morphogenetic protein (BMP) type I receptors ALK2 and ALK3.
More information →
04-0074 2 mg
04-0074-10 10 mg
04-0074-02 2 mg (10 mM in solution)
USA Store UK/Europe Store
PD0325901 (04-0006)
PD03225901 inhibits mitogen-activated protein kinase (MAPK/ERK kinase or MEK) and demonstrates potential antineoplastic activity.
More information →
04-0006 2 mg
04-0006-10 10 mg
04-0006-02 2 mg (10 mM)
USA Store UK/Europe Store
Purmorphamine (04-0009)
Purmorphamine is a Smoothened agonist that promotes the differentiation of human and murine mesenchymal pr ogenitor cells into osteoblasts.
More information →
04-0009 5 mg
USA Store UK/Europe Store
SB431542 (04-0010)
SB421542 is an inhibitor of the transforming growth factor-beta 1 (TGF-β1) activin receptor-like kinases (ALKs).
More information →
04-0010 2 mg
04-0010-05 5 mg (10 mM)
04-0010-10 10 mg
USA Store UK/Europe Store
Sodium Butyrate (04-0005)
Sodium butyrate (butyric acid sodium salt) has been shown to direct the differentiation of mouse ESCs cells into hepatocytes.
More information →
04-0005 500 mg
USA Store UK/Europe Store
Thiazovivin (04-0017)
Thiazovivin is a Rho-associated kinase (ROCK) inhibitor that protects human ESCs in the absence of ECM by regulating E-cadherin mediated cell-cell interaction. Also see “ES Cell Cloning & R ecovery Supplement – Thiazovivin” (01-0014-500).
More information →
04-0017 1 mg
USA Store UK/Europe Store
Valproic Acid (04-0007)
Valproic acid is a histone deacetylase (HDAC) inhibitor which improves reprogramming efficiency by at least 100 fold, and it is reported to regulate the differentiation and proliferation of various cell types.
More information →
04-0007 5 g
USA Store UK/Europe Store
Wnt Inhibitor IWP-2 (04-0034)
Wnt Inhibitor IWP-2 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity. It also blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin.
More information →
04-0034 2 mg
USA Store UK/Europe Store
Wnt Inhibitor IWP-3 (04-0035)
Wnt Inhibitor IWP-3 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity.
More information →
04-0035 2 mg
USA Store UK/Europe Store
Wnt Inhibitor IWP-4 (04-0036)
Wnt Inhbitor IWP-4 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity.
More information →
04-0036 2 mg
04-0036-50 50 mg
USA Store UK/Europe Store
XAV939 (04-0046)
XAV939 is an inhibitor of the Wnt / β-catenin pathway which modulates a number of stem cell behaviors.
More information →
04-0046 2 mg
USA Store UK/Europe Store
Y27632 (04-0012)
Y27632 is an inhibitor of Rho-associated kinase (ROCK) which is widely used to enhance survival of dissociated PSCs. It is common to supplement cell culture medium with 10 µM of ROCK Inhibit or during cell passage or while establishment of spheroids during the first 24 hours.
More information →
04-0012 2 mg
04-0012-10 10 mg
04-0012-02 2 mg (10 mM)
04-0012-H-10 10 mg
USA Store UK/Europe Store

Listed by Product Code

(01-0014-500) hES Cell Cloning & Recovery Supplement
Stemgent hES Cell Cloning & Recover Supplement is a 1000× concentrate of Thiazovivin (2mM). In culture media it significantly improves the likelihood of primaryful sub-cloning from single cells, and increases attachment after passaging. This supplement is a ROCK inhibitor (see Thiazovivin, cat. # 04-0017 for more information).
More information →
01-0014-500 5 × 100 µL

USA Store UK/Europe Store

(04-0004) CHIR99021
CHIR99021 is a highly potent, specific and effective inhibitor of glycogen synthase kinase 3 beta (GSK-3β).
More information →
04-0004 2 mg
04-0004-10 10 mg
04-0004-02 2 mg (10 mM)
USA Store UK/Europe Store
(04-0005) Sodium Butyrate
Sodium butyrate (butyric acid sodium salt) has been shown to direct the differentiation of mouse ESCs cells into hepatocytes.
More information →
04-0005 500 mg
USA Store UK/Europe Store
(04-0006) PD0325901
PD03225901 inhibits mitogen-activated protein kinase (MAPK/ERK kinase or MEK) and demonstrates potential antineoplastic activity.
More information →
04-0006 2 mg
04-0006-10 10 mg
04-0006-02 2 mg (10 mM)
USA Store UK/Europe Store
(04-0007) Valproic Acid
Valproic acid is a histone deacetylase (HDAC) inhibitor which improves reprogramming efficiency by at least 100 fold, and it is reported to regulate the differentiation and proliferation of various cell types.
More information →
04-0007 5 g
USA Store UK/Europe Store
(04-0009) Purmorphamine
Purmorphamine is a Smoothened agonist that promotes the differentiation of human and murine mesenchymal pr ogenitor cells into osteoblasts.
More information →
04-0009 5 mg
USA Store UK/Europe Store
(04-0010) SB431542
SB421542 is an inhibitor of the transforming growth factor-beta 1 (TGF-β1) activin receptor-like kinases (ALKs).
More information →
04-0010 2 mg
04-0010-05 5 mg (10 mM)
04-0010-10 10 mg
USA Store UK/Europe Store
(04-0012) Y27632
Y27632 is an inhibitor of Rho-associated kinase (ROCK) which is widely used to enhance survival of dissociated PSCs. It is common to supplement cell culture medium with 10 µM of ROCK Inhibit or during cell passage or while establishment of spheroids during the first 24 hours.
More information →
04-0012 2 mg
04-0012-10 10 mg
04-0012-02 2 mg (10 mM)
04-0012-H-10 10 mg
USA Store UK/Europe Store
(04-0014) A83-01
A83-01 is a selective inhibitor of the transforming growth factor-beta (TGF-β) type I receptor ALK5, the Activin/Nodal receptor ALK4, and the nodal receptor ALK71.
More information →
04-0014 2 mg
04-0014-10 10 mg
USA Store UK/Europe Store
(04-0015) ALK5 Inhibitor (RepSox)
ALK5 Inhibitor (also known as RepSox, E 616452, and SJN 2511) is a selective and ATP-competitive inhibitor of the TGF-β family type I receptor of activin receptor-like kinase (ALK5).
More information →
04-0015 1 mg
USA Store UK/Europe Store
(04-0016) Doxycycline hyclate
Doxycycline hyclate (dox) is a broad spectrum antibiotic derivative of tetracycline and an inhibitor of matrix metalloproteinases.
More information →
04-0016 10 mg
USA Store UK/Europe Store
(04-0017) Thiazovivin
Thiazovivin is a Rho-associated kinase (ROCK) inhibitor that protects human ESCs in the absence of ECM by regulating E-cadherin mediated cell-cell interaction. Also see “ES Cell Cloning & R ecovery Supplement – Thiazovivin” (01-0014-500).
More information →
04-0017 1 mg
USA Store UK/Europe Store
(04-0021) All-Trans Retinoic Acid
All-Trans Retinoic Acid (ATRA) is the oxidized form of Vitamin A, functioning as a signaling molecule for various developmental pathways that control differentiation and proliferation.
More information →
04-0021 100 mg
USA Store UK/Europe Store
(04-0022) Cyclopamine
Cyclopamine is a steroid alkaloid isolated from the corn lily (Veratrum californicum) that is a Smoothened antagonist involved in both embryogenesis and cancer progression.
More information →
04-0022 2 mg
USA Store UK/Europe Store
(04-0024) Dorsomorphin
Dorsomorphin dihydrochloride (a.k.a. Compound C) is a potent inhibitor of AMP-activated protein kinase (AMPK) and bone morphogenic protein (BMP) signaling.
More information →
04-0024 2 mg
USA Store UK/Europe Store
(04-0025) Forskolin
Forskolin is a natural product adenylate cyclase activator that increases cyclic AMP levels.
More information →
04-0025 2 mg
USA Store UK/Europe Store
(04-0028) KAAD-Cyclopamine
KAAD-cyclopamine is a sonic hedgehog antagonist that targets Smoothened, a 7-transmembrane receptor of the hedgehog signaling pathway.
More information →
04-0028 100 µg
USA Store UK/Europe Store
(04-0034) Wnt Inhibitor IWP-2
Wnt Inhibitor IWP-2 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity. It also blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin.
More information →
04-0034 2 mg
USA Store UK/Europe Store
(04-0035) Wnt Inhibitor IWP-3
Wnt Inhibitor IWP-3 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity.
More information →
04-0035 2 mg
USA Store UK/Europe Store
(04-0036) Wnt Inhibitor IWP-4
Wnt Inhbitor IWP-4 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity.
More information →
04-0036 2 mg
04-0036-50 50 mg
USA Store UK/Europe Store
(04-0041) DAPT
DAPT (a.k.a. GSI-IX or LY-374973) is a cell-permeable dipeptide that inhibits γ-secretase and indirectly inhibits Notch, a γ-secretase substrate.
More information →
04-0041 5 mg
USA Store UK/Europe Store
(04-0046) XAV939
XAV939 is an inhibitor of the Wnt / β-catenin pathway which modulates a number of stem cell behaviors.
More information →
04-0046 2 mg
USA Store UK/Europe Store
(04-0074) LDN-193189
LDN193189 is a cell permeable, small molecule inhibitor of bone morphogenetic protein (BMP) type I receptors ALK2 and ALK3.
More information →
04-0074 2 mg
04-0074-10 10 mg
04-0074-02 2 mg (10 mM in solution)
USA Store UK/Europe Store
(SRP002) ec23
A light-stable pan-RAR receptor agonist that maintains the same biological activity as ATRA (all-trans retinoic acid).
More information →
SRP002 5 mg
SRP002-2 2 × 5 mg
USA Store UK/Europe Store