Purchase product: USA Store
|Product Code||Pack Size||Price in
|Price in EMEA|
|04-0010||5 mg||USD $ 99.00||GBP £ 76.64||EUR € 86.99|
|04-0010-05||5 mg in solution (10 mM)||USD $ 99.00||GBP £ 76.64||EUR € 86.99|
|04-0010-10||10 mg||USD $ 168.00||GBP £ 130.06||EUR € 147.62|
Prices do not include shipping and handling charges.
SB431542 is an inhibitor of the transforming growth factor-β 1 (TGFβ1) activin receptor-like kinases (ALKs). It is a selective and potent inhibitor of ALK-4, -5 and -7. SB431542 inhibits endogenous activin and TGFβ signaling without affecting more divergent BMP signaling utilizing ALK-1, -2, -3, and -61,2. SB431542 stimulates proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells3.
Product Name: Stemolecule SB431542
Catalog Number: 04-0010-base
Alternate Name(s): 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Chemical Formula: C22H16N4O3
Molecular Weight: 384.4
CAS Number: 301836-41-9 (anhydrous)
Purity: Greater than 98 % by HPLC analysis
Reconstitute in DMSO to the desired concentration. For reconstitution instructions please reference product specifications sheet.
Storage and Stability
Store powder at 4 °C protected from light. Information about the stability of Stemolecules in solution is largely not available. As a general guideline, we recommend that stock solution be freshly made and stored in aliquots at −20 °C, protected from light. The effect of storage of stock solutions should be verified for each application.
Quality Control: The purity of SB431542 was determined by HPLC analysis. The accurate mass was determined by mass spectrometry. Cellular toxicity of SB431542 was tested on mouse embryonic stem cells.
Stem Cell Reagents
3D Cell Culture
Zara Puckrin, BSc / 29 April 2021
Zara Puckrin, BSc / 17 March 2021
Zara Puckrin, BSc / 9 March 2021
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