Stemgent Publications:

RNA Reprogramming

Following is a list of publications in scientific journals which use Stemgent RNA reprogramming technologies. For publication which use other Stemgent pages, please see individual products.

StemRNA Clinical iPSC Seed Clones

Making iPSC-derived Therapeutics a Clinical Reality

Zara Puckrin, Sarah Eminli, Robert Annand, Nikola Kolundzic and Amer Rana.
European Biopharmaceutical Review. June 2022

Publications Referencing REPROCELL iPSCs

See also:

• Products: Induced Pluripotent Stem Cells
• REPROCELL US Store: Induced Pluripotent Stem Cells

A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer

Hiroko Shimada, Yuta Sato, Takashi Sasaki, Aki Shimozawa, Kent Imaizumi, Tomoko Shindo, Sachiyo Miyao, Kosuke Kiyama, Takahiro Kondo, Shinsuke Shibata, Seiji Ishii, Junro Kuromitsu, Hirofumi Aoyagi, Daisuke Ito, Hideyuki Okano
Cell Reports Methods. September 2022
DOI: https://doi.org/10.1016/j.crmeth.2022.100289

Direct visualization of the transition status during neural differentiation by dual-fluorescent reporter human pluripotent stem cells

Gwanghyun Park, Minkyung Shin, Wonyoung Lee, Akitsu Hotta, Taeko Kobayashi, Yoichi Kosodo
Stem Cell Reports, August 2022
DOI: https://doi.org/10.1016/j.stemcr.2022.07.001

Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia.

Sonn I; Honda-Ozaki F; Yoshimatsu S; Morimoto S; Watanabe H; Okano H.
Inflammat Regen42:20 (2022)

StemRNA 3^rd Gen Reprogramming Kit

(Cat. No. 00-0076)

Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression.

Seah C; Breen MS; Rusielewicz; Bader HN; Xu C; Hunter CJ; BcCarthy B; Deans PJM; Chattopadhyay; M; Goldberg J; Desarnaud F; Makotkine I; Flory JD; Beirer LM; StaniskyteM; Noggle SA; Huckins LM; Paull D; Brennand KJ; Yehuda R.
Nature Neurosce:https://doi.org/10.1038/s41593-022-01161-y (2022)

Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A>G of unknown pathogenicity in Fabry disease.

Beyer M; Klein T; Klug K; Klopocki E; Üçetker N.
Stem Cell Res61:102747 (2022)

Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions.

Morita K; Nakamura A; Machida M; Kawasaki T; Nakanishi R; Ichida J; Iwata A; Akutsu H.
Regen Therapy21:389 (2022)

Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson’s disease.

Drouin-Ouellet J; Legault EM; Nilsson F; Pircs K ;Bouquety J; Petit F; Shrigley S; Birtele M; Pereira M; Storm P; Sharma Y; Bruzelius A: Vuono R; Kele M; Stoker TB; Ottosson DR; Falk A; Jakobsson J; Barker RA; Parmar M.
Stem Cell Rep17:2203 (2022)

Generation of FOUR iPSC lines (CRICKi004-A; CRICKi005-A; CRICKi006-A, CRICKi007-A) from Spinal muscle atrophy patients with lower extremity dominant (SMALED) phenotype.

Devito LG; Cooper F; D'Angelo I; Smith J; Healy L.
Stem Cell Res65:102954 (2022)

Variation of DNA methylation on the IRX1/2 genes is responsible for the neural differentiation propensity in human induced pluripotent stem cells.

Sekiya A; Takasawa K; Arai Y; Horike S-I; Akutsu H; Umezawa A; Nishio K.
Regen Therapy21:620 (2022)

Clinically compatible advances in blood-derived endothelial progenitor cell isolation and reprogramming for translational applications
Sarah Eminli, Baraa Kwieder, Kevin Yi, Christopher J.Z.Huang, Jung-I lMoon, C-Hong Chang, Fedir N.Kiskin, Nicholas W.Morrell, Brad Hamilton, Amer A.Rana.
New Biotechnology. 63:1-9 (2021)

Using Microfluidics to Generate Human Naïve and Primed Pluripotent Stem Cells. In: Rugg-Gunn P. (eds) Human Naïve Pluripotent Stem Cells.

Zorzan I; Gagliano O; Elvassore N; Martello G.
Meth Mol Biol2416:doi.org/10.1007/978-1-0716-1908-7_5 (2021)

Comparative analysis of human induced pluripotent stem cell-derived mesenchymal stem cells and umbilical cord mesenchymal stem cells.

Rajasingh S; Sigamani V; Selvam V; Gurusamy S; Kirankumar S; Vasanthan J; Rajasingh J.
J Cell Mol Med25:8904 (2021)

Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes.

Yang D; Patel S; Szlachcic J; Scaduto S; Putluri N; Sreekumar A; Suliburk J; Metzker M; Balasubramanyam A; Borowiak M.
Diabetes70:2419 (2021)

Generation of an iPSC cohort of isogenic iPSC lines (46-XY and 47-XXY) from a non-mosaic Klinefelter Syndrome patient (47-XXY) (KAUSTi008-A, KAUSTi008-B, KAUSTi008-C, KAUSTi008-D, KAUSTi008-E, KAUSTi008-F, KAUSTi008-G).

Fiacco E, Alowaysi M; Astro V; Adamo A.
Stem Cell Res 50:102119 (2021)

Generation of iPSC lines (KAUSTi011-A, KAUSTi011-B) from a Saudi patient with epileptic encephalopathy carrying homozygous mutation in the GLP1R gene.

Alowaysi M; Astro V; Fiacco E; Alzahrani F; Alkuraya FS; Adamo A.
Stem Cell Res50:1021 (2021)

Retinal Protection by Sustained Nanoparticle Delivery of Oncostatin M and Ciliary Neurotrophic Factor Into Rodent Models of Retinal Degeneration.

Yang J-Y; Lu B; Feng Q; Alfaro JS; Chen P-H; Loscalzo J; Wei W-B; Zhang Y-Y; Lu S-J; Wang S.
Translational Vision Sci Tech10:6 (2021)

Noonan syndrome patient-specific induced cardiomyocyte model carrying SOS1 gene variant c.1654A>G.

Gurusamy N; Rajasingh S; Sigamani V; Rajasingh R; Isai DG; Czirok A; Bittel D; Rajasingh J.
Exp Cell Research400:112508 (2021)

The combination of dibenzazepine and a DOT1L inhibitor enables a stable maintenance of human naïve-state pluripotency in non-hypoxic conditions.

Isono W; Kawasaki T; Ichida JK; Ayabe T; hiraike O; Umezawa A; Akutsu H.
Regen Therap15:161-168 (2020)

Synthetic mRNA-based differentiation method enables early detection of Parkinson's phenotypes in neurons derived from Gaucher disease-induced pluripotent stem cells.

Akiyama T; Sato S; Ko SBH; Sano O; Sato S; Saito M; Nagai H; Ko MSH; Iwata H.
Stem Cell Transl Med10:572 (2020)

Derivation of two naturally isogenic iPSC lines (KAUSTi006-A and KAUSTi006-B) from a mosaic Klinefelter Syndrome patient (47-XXY/46-XY)

Fiacco E; Alowaysi M; Astro V; Adamo A.
Stem Cell Res 49:102049 (2020).

Establishment of an iPSC cohort from three unrelated 47-XXY Klinefelter Syndrome patients (KAUSTi007-A, KAUSTi007-B, KAUSTi009-A, KAUSTi009-B, KAUSTi010-A, KAUSTi010-B)

Alowaysi M; Fiaccdo E; Astro V; Adamo A.
Stem Cell Res 49:102042 (2020).

Establishment of iPSC lines from a high-grade Klinefelter Syndrome patient (49-XXXXY) and two genetically matched healthy relatives (KAUSTi003-A, KAUSTi004-A, KAUSTi004-B, KAUSTi005-A, KAUSTi005-B, KAUSTi005-C)

Alowaysi M; Fiacco E; Astro V; Adamo A.
Stem Cell Res 49:102008 (2020).

Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation.

Grosch M; Ittermann S; Rusha E; Greisle T; Ori C; Truong D-JJ; O'Niell AC; Pertek A; Westmeyer GG; Drukker M.
BMC Biology 18:42 (2020)

Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates.

Patananan AN; Sercel AJ; Wu T-H; Ahsan FM; Torres Jr. A; Kennendy SAL; Vandiver A; Collier AJ; Mehrabi A; Van Lew J; Zakin L; Rodriguez M; Sixto M; Tadros W; Lazar A; Sieling PA; Nguyen T: Dawson ER; Braas D; Golovato J; Cisneros L; Vaske C; Plath K; Rabizadeh S; Niazi KR; Chiou P-Y; Teitell MA.
Cell Reports33:108562 (2020)

mRNA-based reprogramming under xeno-free and feeder-free conditions.

Jeriha J; Kolundzic N; Khurana P; Perez-Dominguez A; Ilic D.
Meth Mol Biol2454:665 (2020)

IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche.

Wamaitha SE; Grybel KJ; Alanis-Lobato G; Gerri C; Ogushi S; McCarthy A; Kahdevaiah SK; Healy L; Lea RA; Molina-Arcas M; Devito LG; Elder K; Snell P; Christie L; Downward J; Turner JMA; Naikan KK.
Nature Commun 11:764 (2020)

Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions.

Gong J; Cai H; NYSCF Global Stem Array Team; Noggle S; Paull D; Rizzolo LJ; Del Priore LV; Fields MA.
Stem Cells Transl Med :https://doi.org/10.1002/sctm.19-0321 (2019)

Reprogramming and differentiation-dependent transcriptional alteration of DNA damage response and apoptosis genes in human induced pluripotent stem cells.

Shimada M; Tsukada K; Kagawa N; Matsumoto Y.
J Radiation Res 2019:1-10 (2019)

Efficient RNA-mediated reprogramming of human somatic cells to naïve pluripotency facilitated by tankyrase inhibition.

Bredenkamp N; Yang J; Clarke J; Stirparo GG; von Meyenn F; Baker D; Drummond R; Li D; Wu C; Rostovskaya M; Smith A; Guo G.
bioR xiv (2019).
https://doi.org/10.1101/636670

Microfluidic reprogramming to pluripotency of human somatic cells.

Gagliano O; Luni C; Qui W; Bertin E; Torchio E; Galvanin S; Urciuolo A; Elvassore N.
Nat. Protocols 14:772-737 (2019).

Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation.

Liu L-P; Li Y-M; Guo N-N; LI S; Ma X; Zhang Y-X; Gao Y; Huang J-L; Zheng D-X; Wang L-Y; Xu H; Hui L; Zheng Y-W.
Cell Reports 27:455-466.e5 (2019).

Diversity of dermal fibroblasts as major determinant of variability in cell reprogramming.

Sacco AM; Belviso I; Romano V; Carfora A; Schonauer F; Nurzynska D; Montagnani S; Di Meglio F; Castaldo C.
J Cell Mol Med 2019:1-13
https://doi.org/10.1111/jcmm.14316 (2019).

Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy.

Klein T; Klug K; Henkel L; Kwok CK; Edenhofer F; Klopocki E; Kurth I; Üceyler N.
Stem Cell Res 35:101396 (2019).

iPSC generation, prime to naïve reversion and characterization and primordial germ cell differentiation of Northern White Rhino.

Dasgupta B; Rusha E; Drukker M.
Univ Bremen : (2019).

A Renewable Source of Human Beige Adipocytes for Development of Therapies to Treat Metabolic Syndrome.

Su S; Guntur AR; Nguyen DC; Fakory SS; Doucette CC; Leech C; Lotana H; Kelley M; Kohil J; Martino J; Sims-Lucas S; Liaw L; Vary C; Rosen CJ; Brown AC.
Cell Reports 25:3215-3228.e9 (2018).

Generation of the human induced pluripotent stem cell line UKWNLi002-A from dermal fibroblasts of a woman with a heterozygous c.608 C>T (p.Thr203Met) mutation in exon 3 of the nerve growth factor gene potentially associated with hereditary sensory and autonomic neuropathy type 5.

Klein T; Henkel L; Klug K; Kwok CK; Klopocki E; Üceyler N.
Stem Cell Research
https://doi.org/10.1016/j.scr.2018.10.017 (2018)

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming.

Liu X; Nefzger CM; Rossello FH; Chen J; Knaupp AS; Firas J; Ford E; Pflueger J; Paynter JM; Chy HS; O'Brien CM; Huang C; Mishra K; Hodgson-Garms M; Jansz N; Williams SM; Blewitt ME; Nilsson SK; Schittenhelm RL; Laslett AL; Lister R; Polo JM.
Nature Methods 14:1055 (2017)

StemRNA-SR Reprogramming Kit (discontinued)

(Cat. No. 00-0075)

NOTE: This product has been discontinued and is no longer available. Please see the StemRNA 3rd Gen Reprogramming Kit (Cat. No 00-0076) as a replacement.

Generation and characterization of human iPSCs from human fibroblasts in respect to osteochondral regeneration.

Danisovic L; Csobonyeiova M; Nicodemou A; Novakova ZV; Miko M; Zamborsky R; Varga I.
FASEB J 33:Ib168 (2019)

A Rapid and Highly Efficient Method for the Isolation, Purification, and Passaging of Human-Induced Pluripotent Stem Cells.

Gao X; Sprando RL; Yourick JJ.
Cellular Reprogramming 20:282-288 (2018)

Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel.

Goa X; Yourick JJ; Sprando RL.
Stem Cell Research
https://doi.org/10.1016/j.scr.2018.07.013: (2018)

Comparative transcriptomic analysis of endothelial progenitor cells derived from umbilical cord blood and adult peripheral blood: Implications for the generation of induced pluripotent stem cells.

Goa X; Yourick JJ; Sprando RI.
Stem Cell Research 25:202-212 (2017)