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Alvetex Publications: 3D Cell Culture

Alvetex™ is used in scientific research around the world. This page lists the growing body of peer-reviewed publications in scientific journals detailing research where Alvetex has been used. The publications below are hosted on the websites of various scientific journals.

Total publications available:
(130.)

Application of biomimetic surfaces and 3D culture technology to study the role of extracellular matrix interactions in neurite outgrowth and inhibition

K.E.Goncalves, S.Phillips, D.S.H.Shah, D.Athey, S.A.Przyborski
Biomaterials Advances
23 November 2022
DOI: 10.1016/j.bioadv.2022.213204

(129.)

Investigation into the effect of skin tone modulators and exogenous stress on skin pigmentation utilizing a novel bioengineered skin equivalent

Kirsty Goncalves, Paola De Los Santos Gomez, Lydia Costello, Lucy Smith, Hugh Mead, Amy Simpson, Stefan Przyborski
Bioengineering and Translational Medicine
26 September 2022
DOI: 10.1002/btm2.10415

(128.)

Early functional mismatch between breast cancer cells and their tumour microenvironment suppresses long term growth

Anna Perdrix Rosell, Oscar Maiques, Joshua Alexander James Martin, Probir Chakravarty, Luigi Ombrato, Victoria Sanz-Moreno, Ilaria Malanchi
Cancer Letters
28 September 2022
DOI: 10.1016/j.canlet.2022.215800

(127.)

Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway disease

Camilla Margaroli, Hamed Horati, Luke W.Garratt, Vincent D. Giacalone, Craig Schofield, A. Susanne Dittrich, Tim Rosenow, Brian S.Dobosh, Hong S.Lim, Dario L.Frey, Mieke Veltman, George L.Silva, Milton R.Brown, Carsten Schultz, Harm A.W.M.Tiddens, Sarath Ranganathang, Joshua D.Chandler, Peng Qiu, Limin Peng, Bob J.Scholte, Marcus A.Mall, Anthony Kicic, Lokesh Guglani, Stephen M.Stick, Hettie M.Janssens, Rabindra Tirouvanziam
Journal of Cystic Fibrosis
19 June 2022
DOI: 10.1016/j.jcf.2022.06.001

(126.)

Modelling liver cancer microenvironment using a novel 3D culture system

Ala’a Al Hrout, Karla Cervantes-Gracia, Richard Chahwan & Amr Amin
Scientific Reports 12, Article number: 8003 (2022)
14 May 2022
DOI: 10.1038/s41598-022-11641-7

(125.)

Recreating Tissue Structures Representative of Teratomas In Vitro Using a Combination of 3D Cell Culture Technology and Human Embryonic Stem Cells

Alejandro Hidalgo Aguilar, Lucy Smith, Dominic Owens, Rebecca Quelch, and Stefan Przyborski
Bioengineering 2022, 9(5), 185
22 April 2022
DOI: 10.3390/bioengineering9050185

(124.)

In vitro toxicity of glyphosate in Atlantic salmon evaluated with a 3D hepatocyte-kidney co-culture model

L.Søfteland and P.A.Olsvik
Food and Chemical Toxicology, Volumn 164
14 April 2022
DOI: 10.1016/j.fct.2022.113012

(123.)

Biomimetic Full-Thickness Skin-on-a-Chip Based on a Fibroblast-Derived Matrix

Patrícia Zoio, Sara Lopes-Ventura, and Abel Oliva
Micro (MDPI)
12 March 2022
DOI: 10.3390/micro2010013

(122.)

A Novel Coculture System for Assessing Respiratory Sensitizing Potential by IL-4 in T Cells (PDF)

Izuru Mizoguchi, Yasuhiro Katahira, Shinya Inoue, Eri Sakamoto, Aruma Watanabe, Yuma Furusaka, Atsushi Irie, Satoru Senju, Yasuharu Nishimura, Shusaku Mizukami, Kenji Hirayama, Sou Nakamura, Koji Eto, Hideaki Hasegawa and Takayuki Yoshimoto
ALTEX
24 February 2022
DOI: 10.14573/altex.2111181

(121.)

Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization

Emma Nolan, Victoria Louise Bridgeman, Luigi Ombrato, Adam Karoutas, Nicolas Rabas, Celine Angeli Natascha Sewneth, Marcos Vasquez, Felipe Silva Rodrigues, Stuart Horswell, Peter Faull, Rebecca Carter & Ilaria Malanchi
Nat Cancer 3, 173–187 (2022)
24 February 2022
DOI: 10.1038/s43018-022-00336-7

(120.)

Neutrophil-derived extracellular vesicles promote feed-forward inflammasome signaling in cystic fibrosis airways

Osric A Forrest, Brian Dobosh, Sarah A Ingersoll, Sanjana Rao, Alexander Rojas, Julie Laval, Jessica A Alvarez, Milton R Brown, Vin Tangpricha, Rabindra Tirouvanziam
J Leuk Biol
16 February 2022
DOI: 10.1002/JLB.3AB0321-149R

(119.)

Transcriptomic and Functional Evidence Show Similarities between Human Amniotic Epithelial StemCells and Keratinocytes

Li-Ping Liu, Dong-Xu Zheng, Zheng-Fang Xu, Hu-Cheng Zhou, Yun-Cong Wang, Hang Zhou, Jian-Yun Ge, Daisuke Sako, Mi Li, Kazunori Akimoto, Yu-Mei Li, and Yun-Wen Zheng
Cells 2022, 11(1), 70
27 December 2021
DOI: 10.3390/cells11010070

(118.)

miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling

Jie Peng, Susu Shi, Juan Yu, Jianli Liu, Haixiang Wei, Haixia Song, Shaoqiang Wang, Zhejie Li, Shujin He, Lei Li, Hongyan Zhang, Zhizhen Yan, Ran Zhao, Yukun Liu, Yanrong Liu, Junjun Li, Renya Zhang and Wei Wang
Cancer Cell International volume 21, Article number: 702 (2021)
22 December 2021
DOI: 10.1186/s12935-021-02403-y

(117.)

Mass production of human airway-like neutrophils via transmigration in an organotypic model of human airways

Brian Dobosh, Vincent D Giacalone, Camilla Margaroli, Rabindra Tirouvanziam
Star Protocols. Volume 2, Issue 4
17 December 2021
DOI: 10.1016/j.xpro.2021.100892

(116.)

Mechanistic analysis and significance of sphingomyelinasemediated decreases in transepithelial CFTR currents in nHBEs

Kirsten A Cottrill, Vincent D Giacalone, Camilla Margaroli, Robert J Bridges, Michael Koval, Rabindra Tirouvanziam, Nael A McCarty
Physiological Reports.
September 2021
DOI: 10.14814/phy2.15023

(115.)

Derivation of Adult Human Cortical Organotypic Slice Cultures for Coculture with Reprogrammed Neuronal Cells

Giedre Kvist
Methods in Molecular Biology (MIMB), volume 2352
30 July 2021
DOI: 10.1007/978-1-0716-1601-7_17

(114.)

Barrier-on-a-Chip with a Modular Architecture and Integrated Sensors for Real-Time Measurement of Biological Barrier Function

Patrícia Zoio, Sara Lopes-Ventura and Abel Oliva
Micromachines 2021, 12(7), 816
12 July 2021
DOI: 10.3390/mi12070816

(113.)

Pigmented full-thickness human skin model based on a fibroblast-derived matrix for long-term studies

Mrs Patrícia Zoio, Mrs Sara Ventura, Mrs Mafalda Leite, and Dr Abel Oliva
Tissue Engineering Part C: Methods
19 June 2021
DOI: 10.1089/ten.TEC.2021.0069

(112.)

miR-378d regulates polyploidization and malignant phenotype of tumor cells through AKT and RhoA

Jie Peng, Susu Shi, Juan Yu, Jianli Liu, Haixiang Wei, Haixia Song, Shaoqiang Wang, Daolu Guo, Zhejie Li, Shujin He, Lei Li, Hongyan Zhang, Zhizhen Yan, Ran Zhao, Yukun Liu, Yanrong Liu, Junjun Li, Renya Zhang, Wei Wang
Preprints 2021, 2021060443
16 June 2021
DOI: 10.20944/preprints202106.0443.v1

(111.)

Immune modulatory effects of Idelalisib in stromal cells of chronic lymphocytic leukemia

Sarah Handl, Franziska von Heydebrand, Simon Voelkl, Robert A J Oostendorp, Jochen Wilke, Anita N Kremer, Andreas Mackensen, and Gloria Lutzny-Geier
Leukemia and Lymphoma
17 May 2021
DOI: 10.1080/10428194.2021.1927019

(110.)

Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts

L A Smith, A Hidalgo Aguilar, D D G Owens, R H Quelch, E Knight and S A Przyborski
Frontiers in Cell Development and Biology
06 May 2021
DOI: 10.3389/fcell.2021.667246

(109.)

Extracellular Vesicles From a Three-Dimensional Culture of Perivascular Cells Accelerate Skin Wound Healing in a Rat

Min Ho Kim, Changho Chung, Mun Ho Oh, Jin Hyun Jun, Yong Ko and Jong Hun Lee
Aesthetic Plastic Surgery
05 April 2021
DOI: 10.1007/s00266-021-02254-y

(108.)

SIRT1 Inhibits Apoptosis by Promoting Autophagic Flux in Human Nucleus Pulposus Cells in the Key Stage of Degeneration via ERK Signal Pathway

Fei He, Qingshu Li, Bo Sheng, Haitao Yang, and Wei Jiang
BioMed Research International, vol. 2021, Article ID 8818713.
DOI: 10.1155/2021/8818713

(107.)

Use of Porous Polystyrene Scaffolds to Bioengineer Human Epithelial Tissues In Vitro

Costello L, Darling N, Freer M, Bradbury S, Mobbs C, Przyborski S
Methods in Molecular Biology (Clifton, N.J.)
1 January 2021
DOI: 10.1007/978-1-0716-1246-0_20

(106.)

Generation of Keratinocytes from Human Induced Pluripotent Stem Cells Under Defined Culture Conditions

Shyam Kishor Sah, Jitendra K Kanaujiya, I-Ping Chen, and Ernst J Reichenberger
Cellular Reprogramming
29 December 2020
DOI: 10.1089/cell.2020.0046

(105.)

The human bone marrow harbors a CD45CD11B+ cell progenitor permitting rapid microglia-like cell derivative approaches

Andreas Bruzelius Isabel Hidalgo Antonio Boza-Serrano Anna-Giorgia Hjelmér Amelie Tison Tomas Deierborg Johan Bengzon Tania Ramos-Moreno
Stem Cells Translational Medicine
09 December 2020
DOI: 10.1002/sctm.20-0127

(104.)

Exposure of the SH-SY5Y Human Neuroblastoma Cells to 50-Hz Magnetic Field: Comparison Between Two-Dimensional (2D) and Three-Dimensional (3D) In Vitro Cultures

Claudia Consales, Alessio Butera, Caterina Merla, Emanuela Pasquali, Vanni Lopresto, Rosanna Pinto, Maria Pierdomenico, Mariateresa Mancuso, Carmela Marino and Barbara Benassi
Molecular Neurobiology
24 November 2020
DOI: 10.1007/s12035-020-02192-x

(102.)

Bioengineering Novel in vitro Co-culture Models That Represent the Human Intestinal Mucosa With Improved Caco-2 Structure and Barrier Function

Nicole J Darling, Claire L Mobbs, Ariana L González-Hau, Matthew Freer and Stefan Przyborski
Frontiers in Bioengineering and Biotechnology
31 August 2020
DOI: 10.3389/fbioe.2020.00992

(101.)

E7 oncoprotein from human papillomavirus 16 alters claudins expression and the sealing of epithelial tight junctions

Perla Yaceli Uc, Jael Miranda, Arturo Raya-Sandino, Lourdes Alarcón, María Luisa, Roldán Rodolfo, Ocadiz-Delgado, Enoc Mariano Cortés-Malagón, Bibiana Chávez-Munguía, Georgina Ramírez, René Asomoza, Liora Shoshani, Patricio Gariglio, Lorenza González-Mariscal
International Journal of Oncology
29 July 2020
DOI: 10.3892/ijo.2020.5105

(100.)

Spheroid Trapping and Calcium Spike Estimation Techniques toward Automation of 3D Culture

Kenneth Ndyabawe, Mark Haidekker, Amish Asthana, William S Kisaalita
SLAS Technology
16 July 2020
DOI: 10.1177/2472630320938319

(99.)

Grafted human pluripotent stem cell-derived cortical neurons integrate into adult human cortical neural circuitry

Marita Grønning Hansen Cecilia Laterza Sara Palma-Tortosa Giedre Kvist Emanuela Monni Oleg Tsupykov Daniel Tornero Naomi Uoshima Jordi Soriano Johan Bengzon Gianvito Martino Galyna Skibo Olle Lindvall Zaal Kokaia
Stem Cells — Translational Medicine
29 June 2020
DOI: 10.1002/sctm.20-0134

(98.)

Effect of donor age and 3D-cultivation on osteogenic differentiation capacity of adipose-derived mesenchymal stem cells

Stephan Payr, Tim Schuseil, Marina Unger, Claudine Seeliger, Thomas Tiefenboeck, Elizabeth R Balmayor and Martijn van Griensven
Nature – Scientific Reports 10, Article number: 10408 (2020)
26 June 2020
DOI: 10.1038/s41598-020-67254-5

(97.)

Recent developments of 3D models of the tumor microenvironment for cutaneous melanoma: Bridging the gap between the bench and the bedside?

Johanna Maria Hölken and Nicole Elisabeth Teusch
Microorganisms Volume 7: 1-7
7 May 2020
DOI: 10.15761/JTS.1000388

(96.)

Novel 2D and 3D Assays to Determine the Activity of Anti-Leishmanial Drugs

Alec O’Keeffe, Christine Hale, James A. Cotton, Vanessa Yardley, Kapish Gupta, Abhishek Ananthanarayanan, Sudaxshina Murdan, and Simon L Croft
Microorganisms 2020, 8(6), 831
1 June 2020
DOI: 10.3390/microorganisms8060831

(95.)

Modelling human CNS injury with human neural stem cells in 2- and 3-Dimensional cultures

Barbora Vagaska, Olivia Gillham and Patrizia Ferretti
Scientific Reports 10, Article number: 6785(2020)
22 April 2020
DOI: 10.1038/s41598-020-62906-y

(94.)

Applications of novel bioreactor technology to enhance the viability and function of cultured cells and tissues

H W Hoyle, L A Smith, R J Williams and S A Przyborski
The Royal Society — Interface Focus
14 February 2020
DOI: 10.1098/rsfs.2019.0090

(93.)

Apelin Promotes ECM Synthesis by Enhancing Autophagy Flux via TFEB in Human Degenerative NP Cells under Oxidative Stress

Wei Jiang, Pei Zhao, and Xuemei Zhang
Biomed Research Journal
14 February 2020
DOI: 10.1155/2020/4897170

(92.)

Dataset supporting “Multiple scattering in scanning helium microscopy”

Lambrick S, Vozdecky L, Bergin M, Halpin J E, MacLaren D A, Dastoor P C, Przyborski S A, et al.
University of Cambridge, Apollo Repository
31 January 2020
DOI: 10.17863/CAM.48316

(91.)

Micropatterning Method for Porous Materials Using the Difference of the Glass Transition Temperature between Exposed and Unexposed Areas of a Thick-Photoresist

Hidetaka Ueno, Kiichi Sato, Kou Yamada and Takaaki Suzuki
Micromachines
2020. 11(1), 54.
DOI: 10.3390/mi11010054

(90.)

Could 3D models of cancer enhance drug screening?

Virginia Brancato, Joaquim Miguel Oliveira, Vitor Manuel Correlo, Rui Luis Reis, Subhas C.Kunduab
Biomaterials
26 December 2019.
DOI: 10.1016/j.biomaterials.2019.119744

(89.)

Metastatic-niche labelling reveals parenchymal cells with stem features

Luigi Ombrato, Emma Nolan, Ivana Kurelac, Antranik Mavousian, Victoria Louise Bridgeman, Ivonne Heinze, Probir Chakravarty, Stuart Horswell, Estela Gonzalez-Gualda, Giulia Matacchione, Anne Weston, Joanna Kirkpatrick, Ehab Husain, Valerie Speirs, Lucy Collinson, Alessandro Ori, Joo-Hyeon Lee and Ilaria Malanchi
Nature
volume 572, pages 603-608 (2019)
DOI: 10.1038/s41586-019-1487-6

(88.)

Emulsion templated scaffolds manufactured from photocurable polycaprolactone

Betül Aldemir Dikici, Colin Sherborne, Gwendolen C.Reilly, Frederik Claeyssens
Science Direct
26 June 2019
DOI: 10.1016/j.polymer.2019.05.023

(87.)

Engineering a Multilayered Skin Equivalent: The Importance of Endogenous Extracellular Matrix Maturation to Provide Robustness and Reproducibility

Lydia Costello, Nicola Fullard, Mathilde Roger, Steven Bradbury, Teresa Dicolandrea, Robert Isfort, Charles Bascom, Stefan Przyborski
Skin Tissue Engineering
31 May 2019
DOI: 10.1007/978-1-4939-9473-1_9

(86.)

Osteogenic differentiation of human adipose-derived stem cells in 3D conditions - comparison of spheroids and polystyrene scaffolds

Rumiński S, Kalaszczyńska I, Długosz A, Lewandowska-Szumieł M.
Eur Cell Mater
17 May 2019
DOI: 10.22203/eCM.v037a23

(85.)

CAFs and TGF-β Signaling Activation by Mast Cells Contribute to Resistance to Gemcitabine/Nabpaclitaxel in Pancreatic Cancer

Letizia Porcelli, Rosa Maria Iacobazzi, Roberta Di Fonte, Simona Serratì, Angelica Intini, Antonio Giovanni Solimando, Oronzo Brunetti, Angela Calabrese, Francesco Leonetti, Amalia Azzariti and Nicola Silvestris
Cancers 2019, 11, 330
7 March 2019
DOI: 10.3390/cancers11030330

(84.)

Neutrophil Dysfunction in the Airways of Children with Acute Respiratory Failure Due to Lower Respiratory Tract Viral and Bacterial Coinfections

Jocelyn R Grunwell, Vincent D Giacalone, Susan Stephenson, Camilla Margaroli, Brian S Dobosh, Milton R Brown, Anne M Fitzpatrick and Rabindra Tirouvanziam
Nature – Scientific Reports 9, Article number: 2874 (2019)
27 February 2019
DOI: 10.1038/s41598-019-39726-w

(83.)

Bioengineering the microanatomy of human skin

Mathilde Roger, Nicola Fullard, Lydia Costello, Steven Bradbury, Ewa Markiewicz, Steven O'Reilly, Nicole Darling, Pamela Ritchie, Arto Määttä, Iakowos Karakesisoglou, Glyn Nelson, Thomas von Zglinicki, Teresa Dicolandrea, Robert Isfort, Charles Bascom, Stefan Przyborski
Journal of Anatomy
10 February 2019
DOI: 10.1111/joa.12942

(82.)

A multifunctional drug nanocarrier for efficient anticancer therapy

Carmen Teijeiro-Valiño, Ramon Novoa-Carballal, Erea Borrajo, Anxo Vidal, Marta Alonso-Nocelo, Maríade la Fuente Freire, Pedro P Lopez-Casas, Manuel Hidalgo, Noémi Csaba, María José Alonso
Journal of Controlled Release.
28 January 2019.
DOI: 10.1016/j.jconrel.2018.12.002

(81.)

Preparation of 3D porous hydroxyapatite cell scaffolds using polystyrene templates under biomimetic conditions

Kazutoshi IIJIMA, Ayako IIZUKA, Ryo SUZUKI, Hitomi UENO-YOKOHATA3, Nobutaka KIYOKAWA, Mineo HASHIZUME
Journal of the Ceramic Society of Japan 126 [11] 956-958 2018
November 2018
DOI: 10.2109/jcersj2.18144

(80.)

Glioblastoma’s Next Top Model: novel culture systems for brain cancer radiotherapy research

Seamus P Caragher, Anthony J Chalmers MD/PhD, Natividad Gomez-Roman PhD
Preprints 2018, 2018100697
30 October 2018
DOI: 10.20944/preprints201810.0697.v1

(79.)

Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor

J P Zepecki, K M Snyder, M M Moreno, E Fajardo, A Fiser, J Ness, A Sarkar, S A Toms and N Tapinos
Oncogene
23 October 2018
DOI: 10.1038/s41388-018-0546-z

(78.)

Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers

Giedre Miskinyte, Marita Grønning Hansen, Emanuela Monni, Matti Lam, Johan Bengzon, Olle Lindvall, Henrik Ahlenius, Zaal Kokaia
ACS Omega 2018, 3 (8), pp 10180-10187
11 October 2018
DOI: 10.1371/journal.pone.0204688

(77.)

Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells in Electrospun Silica Nonwoven Fabrics

Kazutoshi Iijima, Shohei Ishikawa, Kohei Sasaki, Mineo Hashizume, Masaaki Kawabe, and Hidenori Otsuka
ACS Omega 2018, 3 (8), pp 10180-10187
30 August 2018
DOI: 10.1021/acsomega.8b01139

(76.)

The tyrosine phosphorylated pro-survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway

Ngoc Ly Ta, Krittalak Chakrabandhu, Sébastien Huault and Anne-Odile Hueber
Scientific Reports volume 8, Article number: 12424 (2018)
20 August 2018
DOI:10.1038/s41598-018-30804-z

(75.)

Host-pathogen-interaction reconstituted in 3-dimensional cocultures of mucosa and C. albicans

Mrs Romina Buchs, Mr Bruno Lehner, Dr Phillippe Meuwly, Prof Bruno Schnyder
Tissue Engineering Part C: Methods
14 June 2018
DOI: 10.1089/ten.TEC.2018.0042

(74.)

Frontline Science: Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosis

Osric A Forrest, Sarah A Ingersoll, Marcela K Preininger, Julie Laval, Dominique H Limoli, Milton R Brown, Frances E Lee, Brahmchetna Bedi, Ruxana T Sadikot, Joanna B Goldberg, Vin Tangpricha, Amit Gaggar, Rabindra Tirouvanziam
Journal of Leukocyte Biology
09 May 2018
DOI: 10.1002/JLB.5HI1117-454RR

(73.)

Differentiation Patterns of Immortalized Human Meibomian Gland Epithelial Cells in Three-Dimensional Culture

Nagayoshi Asano, Ulrike Hampel, Fabian Garreis, Antje Schröder, Martin Schicht, Christian M Hammer, Friedrich Paulsen
Investigative Ophthalmology and Visual Science, Vol.59, 1343-1353
March 2018
DOI: 10.1167/iovs.17-23266

(72.)

Development of a microfluidic perfusion 3-dimensional cell culture system

Dong Hyeok Park, Hyeong Jin Jeon, Moon Jeong Kim, Xuan Don Nguyen, Karl Morten and Jeung Sang Go
Journal of Micromechanics and Microengineering
17 January 2018
DOI: 10.1088/1361-6439/aaa877

(71.)

Substrate Microarchitecture Shapes the Paracrine Crosstalk of Stem Cells with Endothelial Cells and Osteoblasts

Francisco Martín-Saavedra, Lara Crespo, Clara Escudero-Duch, Laura Saldaña, Enrique Gómez-Barrena and Nuria Vilaboa
Scientific Reports 7 Article number: 15182
9 November 2017
DOI: 10.1038/s41598-017-15036-x

(70.)

Paracrine interactions between mesenchymal stem cells and macrophages are regulated by 1,25-dihydroxyvitamin D3

Laura Saldaña, Gema Vallés, Fátima Bensiamar, Francisco José Mancebo, Eduardo García-Rey and Nuria Vilaboa
Scientific Reports 7, Article number: 14618
3 November 2017
doi:10.1038/s41598-017-15217-8

(69.)

Effect of_the Scaffold Microenvironment on Cell Polarizability and Capacitance Determined by Probabilistic Computations

Pazmino Betancourt B, Florczyk S, Simon M, Juba D, Douglas JF, Keyrouz W, Bajcsy P, Lee C, Simon CG
Biomedical Materials
26 October 2017
DOI: 10.1088/1748-605X/aa9650

(68.)

Increased sphingosine-1-phosphate production in response to osteocyte mechanotransduction

Cale Dobrosak, Jonathan H Gooi
J. Bone Reports
16 October 2017
DOI: 10.1016/j.bonr.2017.10.002

(67.)

Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation

Michel C, Miller CN, Küchler R, Brors B, Anderson MS, Kyewski B, Pinto S
J Immunol. pii: ji1700203
9 October 2017
doi: 10.4049/jimmunol.1700203

(66.)

Autocrine and Paracrine Regulation of the Murine Skeleton by Osteocyte-Derived Parathyroid Hormone-Related Protein

Ansari N, Ho PW, Crimeen-Irwin B, Poulton IJ, Brunt AR, Forwood MR, Divieti Pajevic P, Gooi JH, Martin TJ, Sims NA
J Bone Miner Res
15 September 2017
DOI: 10.1002/jbmr.3291

(65.)

A Bioinformatics 3D Cellular Morphotyping Strategy for Assessing Biomaterial Scaffold Niches

S Florczyk, M Simon, D Juba, S Pine, S Sarkar, D Chen, P Baker, S Bodhak, A Cardone, M Brady, P Bajcsy, C G Simon
ACS Biomater Sci Eng
31 August 2017
DOI: 10.1021/acsbiomaterials.7b00473

(64.)

Galectin-1 from conditioned medium of three-dimensional culture of adipose-derived stem cells accelerates migration and proliferation of human keratinocytes and fibroblasts

MH Kim, WH Wu, JH Choi, JH Kim, JH Jun, Y Ko and JH Lee MD
Wound Repair and Regeneration
30 August 2017
DOI: 10.1111/wrr.12579

(63.)

SHH signalling mediates astrocyte crosstalk with neurons to confer neuroprotection

Ugbode CI, Smith I, Whalley BJ, Hirst WD, Rattray M
J Neurochem
9 May 2017
doi: 10.1111/jnc.14064

(62.)

Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells

Niu N, Mercado-Uribe I, Liu J
Oncogene
24 April 2017
DOI: 10.1038/onc.2017.72

(61.)

Osteocyte secreted factors inhibit skeletal muscle differentiation

Wood CL, Divieti Pajevic P, Gooi JH
Bone Reports. p74-80.
6 June 2017
DOI: 10.1016/j.bonr.2017.02.007

(60.)

Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901

Shannon S, Jia D, Entersz I, Beelen P, Yu M, Carcione C, Carcione J, Mahtabfar A, Vaca C, Weaver M, Shreiber D, Zahn JD, Liu L, Lin H, Foty RA
BMC Cancer. 17(1):121.
10 February 2017
doi: 10.1186/s12885-017-3107-x

(59.)

A robust and reproducible human pluripotent stem cell derived model of neurite outgrowth in a three-dimensional culture system and its application to study neurite inhibition

Clarke KE, Tams DM, Henderson AP, Roger MF, Whiting A, Przyborski SA
Neurochem Int. pii: S0197-0186(16)30507-1
20 December 2016
DOI: 10.1016/j.neuint.2016.12.009

(58.)

Synthesis of Near-Infrared Fluorescent Two-Photon-Absorbing Fluorenyl Benzothiadiazole and Benzoselenadiazole Derivatives

Sheng Yao, Bosung Kim, Xiling Yue, Maria Y. Colon Gomez, Mykhailo V. Bondar, and Kevin D. Belfield
ACS Omega, 2016, 1 (6), pp 1149-1156
7 December 2016
DOI: 10.1021/acsomega.6b00289

(57.)

A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses

Natividad Gomez-Roman, Katrina Stevenson, Lesley Gilmour, Graham Hamilton and Anthony J Chalmers
Neuro Oncology
30 August 2016
DOI: 10.1093/neuonc/now164

(56.)

Bcl-xL is an oncogenic driver in colorectal cancer

Scherr AL, Gdynia G, Salou M, Radhakrishnan P, Duglova K, Heller A, Keim S, Kautz N, Jassowicz A, Elssner C, He YW, Jaeger D, Heikenwalder M, Schneider M, Weber A, Roth W, Schulze-Bergkamen H, Koehler BC
Cell Death Dis. 7(8):e2342
18 August 2016
DOI: 10.1038/cddis.2016.233

(55.)

The dual role of asporin in breast cancer progression

Simkova D, Kharaishvili G, Korinkova G, Ozdian T, Suchánková-Kleplová T, Soukup T, Krupka M, Galandakova A, Dzubak P, Janikova M, Navratil J, Kahounova Z, Soucek K, Bouchal J
Oncotarget
7 July 2016
DOI: 10.18632/oncotarget.10471

(54.)

TDP-43 regulates endogenous retrovirus-K viral protein accumulation

Manghera M, Ferguson-Parry J, Douville RN
Neurobiol Dis. 94:226-36
October 2016
DOI: 10.1016/j.nbd.2016.06.017

(53.)

Influence of Matrices on 3D-Cultured Prostate Cancer Cells’ Drug Response and Expression of Drug-Action Associated Proteins

Edmondson R, Adcock AF, Yang L
Public Library of Science. PloS ONE 11(6):e0158116
28 June 2016
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Structural Analysis of Three-dimensional Human Neural Tissue derived from Induced Pluripotent Stem Cells

Patrick Terrence Brooks, Mikkel Aabech Rasmussen and Poul Hyttel
J Stem Cell Res Ther 6:4
2016
DOI: 10.4172/2157-7633.1000337

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Astrocytes Grown in Alvetex Three Dimensional Scaffolds Retain a Non-reactive Phenotype

Ugbode CI, Hirst WD, Rattray M
Neurochem Res. 41(8):1857-67
21 April 2016
doi: 10.1007/s11064-016-1911-3

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3D Reconstruction of the Human Airway Mucosa In Vitro as an Experimental Model to Study NTHi Infections

Pasquale Marrazzo, Silvia Maccari, Annarita Taddei, Luke Bevan, John Telford, Marco Soriani, Alfredo Pezzicoli
Public Library of Science. PLoS ONE
April 21, 2016
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Comparison of the Osteogenic Potential of Mineral Trioxide Aggregate and Endosequence Root Repair Material in a 3-dimensional Culture System

Rifaey HS, Villa M, Zhu Q, Wang YH, Safavi K, Chen IP
J Endod. 2016 42(5):760-5
16 March 2016
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Preclinical evaluation of the AR inhibitor enzalutamide in triple-negative breast cancer cells

Caiazza F, Murray A, Madden SF, Synnott NC, Ryan EJ, O’Donovan N, Crown J, Duffy MJ
Endocr Relat Cancer. 2016 Apr; 23(4):323-34
1 March 2016
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Oxygen-sensing scaffolds for 3-dimensional cell and tissue culture

James Jenkins, Ruslan I Dmitriev, Karl Morten, Kieran W McDermott, Dmitri B Papkovsky
Acta Biomaterialia
31 January 2015
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Novel Three Dimensional Human Endocervix Cultures respond to 28-day hormone treatment

Sevim Yildiz Arslan, Yanni Yu, Joanne E. Burdette, Mary Ellen Pavone, Thomas J Hope, Teresa K Woodruff, J Julie Kim
Endocrinology
30 Jan 2015
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Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices

Emma J Davies, Meng Dong, Matthias Gutekunst, Katja Närhi, Hanneke JAA van Zoggel, Sami Blom, Ashwini Nagaraj, Tauno Metsalu, Eva Oswald, Sigrun Erkens-Schulze, Juan A Delgado San Martin, Riku Turkki, Stephen R Wedge, Taija M af Hällström, Julia Schueler, Wytske M van Weerden, Emmy W Verschuren, Simon T Barry, Heiko van der Kuip and John A Hickman
Nature-Scientific Reports 5, Article number: 17187 (2015)
9 December 2015
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Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes

Lara Stevanato, Caroline Hicks, John D. Sinden
Journal of Visualized Experiments (98), e52410
12 April 2015
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Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways

Gabriela Martínez-Revollar, Erika Garay, Dolores Martin-Tapia, Porfirio Nava, Miriam Huerta, Esther Lopez-Bayghen, Noemí Meraz-Cruz, José Segovia, Lorenza González-Mariscal
Experimental Cell Research. 339(1) pages 67-80
15 November 2015
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Neuronal-glial populations form functional networks in a biocompatible 3D scaffold

Imogen Smith, Marcus Haag, Christopher Ugbode, Daniel Tams, Marcus Rattray, Stefan Przyborski, Angela Bithell, Benjamin J Whalley
J Neuroscience Letters
19 October 2015
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A Novel Fully Humanized 3D Skin Equivalent to Model Early Melanoma Invasion

David S Hill, Neil D P Robinson, Matthew P Caley, Mei Chen, Edel A O’Toole, Jane L Armstrong, Stefan Przyborski, and Penny E Lovat
Molecular Cancer Therapeutics.
1 September 2015
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Dexamethasone-Mediated Activation of Fibronectin Matrix Assembly Reduces Dispersal of Primary Human Glioblastoma Cells

S Shannon, C Vaca, D Jia, I Entersz, et al.
Public Library of Science. PloS ONE, 2015
18 August 2015
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A method for the evaluation of thousands of automated 3D stem cell segmentations

Bajcsy P, Simon M, Florczyk SJ, Simon CG Jr, Juba D, Brady MC.
J Microsc. 260(3):363-76
13 August 2015
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Two and three dimensional graphene substrates to magnify osteogenic differentiation of periodontal ligament stem cells

Han Xie, Tong Cao, José Viana Gomes, Antônio Hélio Castro Neto, Vinicius Rosa
Carbon. Volume 93
November 2015
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The Wnt-inhibitor Sclerostin is Up-regulated by Mechanical Unloading in Osteocytes in vitro

Jordan M Spatz, Marc N Wein, Jonathan H Gooi, Yili Qu, Jenna L Garr, Shawn Liu, Kevin J Barry, Yuhei Uda, Forest Lai, Christopher Dedic, Mercedes Balcells-Camps, Henry M Kronenberg, Philip Babij, Paola Divieti Pajevic
Journal of Biological Chemistry
7 May 2015
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Increased survival and exocytosis of toxic primary granules by neutrophils in an in vitro model of Cystic Fibrosis airway disease (INC6P.310)

Osric Forrest, Sarah Ingersoll, Marcela Preininger, Julie Laval, Milton Brown and Rabindra Tirouvanziam
Journal of immunology vol.194 (1 Supplement) 192.12.
1 May 2015

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Targeting ADAM-17 with an inhibitory monoclonal antibody has antitumour effects in triple negative breast cancer cells

F Caiazza, P M McGowan, M Mullooly, A Murray, N Synnott, N O’Donovan, L Flanagan, C J Tape, G Murphy, J Crown and M J Duffy
British Journal of Cancer
26 May 2015
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Human neural stem cell-derived cultures in three-dimensional substrates form spontaneously functional neuronal networks

Imogen Smith, Vasco Silveirinha, Jason L Stein, Luis de la Torre-Ubieta, Jonathan A Farrimond, Elizabeth M Williamson and Benjamin J Whalley
Journal of Tissue Engineering and Regenerative Medicine
25 February 2015
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Assessing Na+/H+exchange and cell effector functionality in metastatic breast cancer

Schammim Ray Amith, Jodi Marie Wilkinson, Larry Fliegel
J Biochimie Open. 6. 2 (2016) 16-23
27 January 2015
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Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles

Ruslan I Dmitriev, Sergey M Borisov, Alina V Kondrashina, Janelle MP Pakan, Ujval Anilkumar, Jochen H M Prehn, Alexander V Zhdanov, Kieran W McDermott, Ingo Klimant, Dmitri B Papkovsky
Cellular and Molecular Life Sciences (2015) 72:367-381
January 2015
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Development of positive control tissue for in situ hybridisation using Alvetex scaffolds

Christa MacDonald, David Benjamin Finlay, Anower Jabed, Michelle Glass, E Scott Graham
Journal of Neuroscience Methods
30 December 2014
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Topographical cues regulate the crosstalk between MSCs and macrophages

Gema Vallés, Fátima Bensiamar, Lara Crespo, Manuel Arruebo, Nuria Vilaboa, Laura Saldaña
Biomaterials
October 28, 2014
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Pan-Bcl-2 Inhibitor Obatoclax Delays Cell Cycle Progression and Blocks Migration of Colorectal Cancer Cells

Bruno Christian Koehler, Anna-Lena Scherr, Stephan Lorenz, Christin Elssner, Nicole Kautz, Stefan Welte, Dirk Jaeger, Toni Urbanik, Henning Schulze-Bergkamen
Public Library of Science. Plos ONE 9(9): e106571.
5 September 2014
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Chondrogenic potential of human articular chondrocytes and skeletal stem cells: A comparative study

Siwei Li, Bram G Sengers, Richard OC Oreffo and Rahul S Tare
Journal of Biomaterials Applications
20 August 2014
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Morphology and functions of astrocytes cultured on water-repellent fractal tripalmitin surfaces

Wei-wei Hu, Zhe Wang, Shan-shan Zhang, Lei Jiang, Jing Zhang, Xiangnan Zhang, Qun-fang Lei, Hyun-Joo Park, Wen-jun Fang, Zhong Chen
Biomaterials 2014
2 June 2014
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The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells

Zuzana Pernicová, Eva Slabáková, Radek Fedr, Šárka Šimečková, Josef Jaroš, Tereza Suchánková, Jan Bouchal, Gvantsa Kharaishvili, Milan Král, Alois Kozubík and Karel Souček
Molecular Cancer 2014, 13:113
20 May 2014
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The effects of microRNAs on human neural stem cell differentiation in two- and three-dimensional cultures

Lara Stevanato and John D Sinden
Stem Cell Research and Therapy 2014, 5:49
11 April 2014
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Small molecule phosphorescent probes for O2 imaging in 3D tissue models

Ruslan I Dmitriev, Alina V Kondrashina, Klaus Koren, Ingo Klimant, Alexander V Zhdanov, Janelle MP Pakan, Kieran W McDermott and Dmitri B Papkovsky
Biomaterials Science
28 January 2014
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Hanging drop: An in vitro air toxic exposure model using human lung cells in 2D and 3D structures

Faye F Liu, Cheng Peng, Beate I Escher, Emmanuelle Fantino, Cindy Giles, Stephen Were, Lesley Duffy, Jack C. Ng
Journal of Hazardous Materials
15 October 2013
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Beyond Cell Death - Antiapoptotic Bcl-2 Proteins Regulate Migration and Invasion of Colorectal Cancer Cells In Vitro

Bruno Christian Koehler, Anna-Lena Scherr, Stephan Lorenz, Toni Urbanik, Nicole Kautz, Christin Elssner, Stefan Welte, Justo Lorenzo Bermejo, Dirk Jäger, Henning Schulze-Bergkamen
Public Library of Science. PLoS ONE 8(10): e76446
3 October 2013
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Effect of PEG Surface Conformation on Anticancer Activity and Blood Circulation of Nanoemulsions Loaded with Tocotrienol-Rich Fraction of Palm Oil

Alaadin Alayoubi, Saeed Alqahtani, Amal Kaddoumi, Sami Nazzal
The AAPS Journal
30 August 2013
DOI: 10.1208/s12248-013-9525-z

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Overlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity

Sheena Pinto, Chloé Michela, Hannah Schmidt-Glenewinkel, Nathalie Harder, Karl Rohr, Stefan Wild, Benedikt Brorse, and Bruno Kyewskia
PNAS.
26 August 2013
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Epidermal-like architecture obtained from equine keratinocytes in three-dimensional cultures

Ruchi Sharma, Safia Z Barakzai, Sarah E Taylor, F Xavier Donadeu
Journal of Tissue Engineering and Regenerative Medicine
30 July 2013
DOI: 10.1002/term.1788

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Targeting of Beta Adrenergic Receptors Results in Therapeutic Efficacy against Models of Hemangioendothelioma and Angiosarcoma

Jessica M Stiles, Clarissa Amaya, Steven Rains, Dolores Diaz, Robert Pham, James Battiste, Jaime F Modiano, Victor Kokta, Laura E Boucheron, Dianne C Mitchell, Brad A Bryan
Public Library of Science. PLoS ONE 8(3): e60021
28 March 2013
DOI: 10.1371/journal.pone.0060021

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Characterization of liver specific functions of upcyte® hepatocytes grown in 3D and co-cultured with upcyte® endothelial cells

Dähn C, Hewitt N, Maltman D, Talas G, Przyborski S, Heinz S, Nörenberg A, Scheller K, Braspenning J
Z Gastroenterol, 2012; 50 - P2_05
2012
DOI: 10.1055/s-0031-1295802

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Generation of proliferating human hepatocytes using upcyte® technology: characterisation and applications in induction and cytotoxicity assays

Alexandra Burkard, Caroline Dähn, Stefan Heinz, Anne Zutavern, Vera Sonntag-Buck, Daniel Maltman, Stefan Przyborski, Nicola J. Hewitt, and Joris Braspenning
Xenobiotica
October 2012
DOI: 10.3109/00498254.2012.675093

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The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells

Galavotti S, Bartesaghi S, Faccenda D, Shaked-Rabi M, Sanzone S, McEvoy A, Dinsdale D, Condorelli F, Brandner S, Campanella M, Grose R, Jones C, Salomoni P
Oncogene
23 April 2012
DOI: 10.1038/ocn.2012.111

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Rat primary hepatocytes show enhanced performance and sensitivity to acetaminophen during three-dimensional culture on a polystyrene scaffold designed for routine use

Schutte M, Fox B, Baradez M, Devonshire A, Minguez J, Bokhari M, Przyborski S, Marshall D
Assay and Drug Development Technologies
October 2011
DOI: 10.1089/adt.2011.0371

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Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours

Rajan N, Elliott R, Clewes O, Mackay A, Reis-Filho JS, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A
Oncogene
13 October 2011
DOI: 10.1038/onc.2011.133

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Adipose tissue-derived stem cells display a proangiogenic phenotype on 3D scaffolds.

Neofytou EA, Chang E, Patlola B, Joubert LM, Rajadas J, Gambhir SS, Cheng Z, Robbins RC, Beygui RE
Journal Biomedical Materials Research Part A
1 September 2011
DOI: 10.1002/jbm.a.33113

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Alvetex: Polystyrene scaffold technology for routine three dimensional cell culture.

Knight E, Murray B, Carnachan R, Przyborski SA
Methods in Molecular Biology (2011), 695, 323-40.
DOI: 10.1007/978-1-60761-984-0_20

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Validation of reference gene stability for APAP hepatotoxicity studies in different in vitro systems and identification of novel potential toxicity biomarkers

Bridget C Fox, Alison S Devonshire, Maaike E Schutte, Carole A Foy, Jesus Minguez, Stefan Przyborski, Daniel Maltman, Maria Bokhari, Damian Marshall
Toxicology In Vitro, Volume 24, Issue 7, October 2010, Pages 1962-1970
October 2010
doi:10.1016/j.tiv.2010.08.007

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Developments in three dimensional cell culture technology aimed at improving the accuracy of in vitro analyses

Maltman D, Przyborski SA
Biochemical Society Transactions (2010), 38(4), 1072-5
August 2010
DOI: 10.1042/BST0381072

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Emulsion-templated porous scaffolds enabling three dimensional cell culture. Polymer Preprints

Carnachan RJ, Bokhari M, Maatta A, Cameron NR, Przyborski SA

Journal or Materials Chemistry
12 Jul 2007
DOI: 10.1039/B707499A

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Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge

Bokhari M, Carnachan R, Cameron NR, Przyborski SA
Journal of Anatomy (2007), 211, 567-76.
15 August 2007
DOI: 10.1111/j.1469-7580.2007.00778.x

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Effect of synthesis parameters on emulsion-templated porous polymer formation and evaluation for 3D cell culture scaffolds

Bokhari M, Carnachan R, Przyborski SA, Cameron NR
Journal of Materials Chemistry (2007), 17, 4088-4094
12 July 2007
DOI: 10.1039/B707499A

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Novel cell culture device enabling three-dimensional cell growth and improved cell function

Bokhari M, Carnachan R, Cameron NR, Przyborski, SA
Biochemical and Biophysical Research Communications (2007), 354, 1095-1100
6 January 2007
DOI: 10.1016/j.bbrc.2007.01.105

(4.)

Tailoring the morphology of emulsion-templated porous polymers

Carnachan RJ, Bokhari M, Przyborski SA, Cameron NR
Soft Matter (2006), 2, 608-616
23 May 2006
DOI: 10.1039/B603211G

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Porous polymers by emulsion templating

Barbetta A, Carnachan RJ, Smith KH, Zhao C, Cameron NR, Kataky R, Hayman M, Przyborski SA, Swan M
Macromolecular Symposia, 226, 203-211.
20 June 2005
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Growth of human stem cell-derived neurons on solid three dimensional polymers

Hayman MW, Smith KH, Cameron NR, Przyborski SA
Journal of Biochemical and Biophysical Methods (2005), 62, 231-240
31 March 2005
DOI: 10.1016/j.jbbm.2004.12.001

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Enhanced neurite outgrowth by human neurons grown on solid three-dimensional scaffolds

Hayman MW, Smith KH, Cameron NR, Przyborski SA
Biochemical and Biophysical Research Communications (2004), 314, 483-488.
6 February 2004
DOI: 10.1016/j.bbrc.2003.12.135