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Merkel cell polyomavirus is not detected in mesotheliomas

Bhatia K, Modali R, Goedert JJ.

J Clin Virol. 2010 Feb;47(2):196-8. Epub 2009 Dec 16.


Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention Trial

Murphy G, Cross AJ, Sansbury LS, Bergen A, Laiyemo AO, Albert PS, Wang Z, Yu B, Lehman T, Kalidindi A, Modali R, Schatzkin A, Lanza E.

Int J Cancer. 2009 May 1;124(9):2148-51.


Merkel cell carcinoma subgroups by Merkel cell polyomavirus DNA relative abundance and oncogene expression

Bhatia K, Goedert JJ, Modali R, Preiss L, Ayers LW.

Int J Cancer. 2009 Jun 23;126(9):2240-2246.


Immunological detection of viral large T antigen identifies a subset of Merkel cell carcinoma tumors with higher viral abundance and better clinical outcome

Bhatia K, Goedert JJ, Modali R, Preiss L, Ayers LW.

Int J Cancer. 2009 Dec 29.


Polynucleotide kinase 3′ phosphatase variant, dietary variables and risk of adenoma recurrence in the Polyp Prevention Trial

Murphy G, Sansbury LS, Bergen AW, Wang Z, Schatzkin A, Lehman T, Kalidindi A, Modali R, Lanza E.

Eur J Cancer Prev. 2008 Jun;17(3):287-90.


Effect modification by catalase genotype suggests a role for oxidative stress in the association of hormone replacement therapy with postmenopausal breast cancer risk

Quick Sylvia K; Shields Peter G; Nie Jing; Platek Mary E; McCann Susan E; Hutson Alan D; Trevisan Maurizio; Vito Dominica; Modali Ramakrishna; Lehman Teresa A; Seddon Mike; Edge Stephen B; Marian Catalin; Muti Paola; Freudenheim Jo L.

Cancer epidemiology, biomarkers and prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(5):1082-7.


Folate and MTHFR: risk of adenoma recurrence in the Polyp Prevention Trial

Murphy G, Sansbury LB, Cross AJ, Stolzenberg-Solomon R, Laiyemo A, Albert PS, Wang Z, Schatzkin A, Lehman T, Kalidindi A, Modali R, Lanza E.

Cancer Causes Control. 2008 Sep; 19(7):751-8. Epub 2008 Mar 6.


Inflammatory cytokine gene polymorphisms, nonsteroidal anti-inflammatory drug use, and risk of adenoma polyp recurrence in the polyp prevention trial

Sansbury, L.B., Bergen, A.W., Wanke, K.L., Yu, B., Caporaso, N.E., Chatterjee, N., Ratnasinghe, L., Schatzkin, A., Lehman, T.A., Kalidindi, A., Modali, R., Lanza, E.

Cancer Epidemiol Biomarkers Prev. 2006 Mar; 15(3):494-501.


Catechol-O-methyltransferase haplotypes and breast cancer among women on Long Island, New York

Gaudet, M.M., Bensen, J.T., Schroeder, J., Olshan, A.F., Terry, M.B., Eng, S.M., Teitelbaum, S.L., Britton, J.A., Lehman, T.A., Neugut, A.I., Ambrosone, C.B., Santella, R.M., Gammon, M.D.

Breast Cancer Res Treat. 2006 Apr 5; [Epub ahead of print].


FcRI{gamma}IIa and FcR{gamma}IIa Polymorphisms May Not Correlate with Response to Alemtuzumab (Campath-1H) in Chronic Lymphocytic Leukemia (CLL)

Lin, T.S., Flinn, I.W., Modali, R., Lehman, T.A., Webb, J., Waymer, S., Moran, M.E., Lucas, M.S., Sherif, F.S., Byrd, J.C.

Blood 105: 289-291, 2005.


CYP3A43 Pro(340)Ala polymorphism and prostate cancer risk in African Americans and Caucasians

Stone A, Ratnasinghe LD, Emerson GL, Modali R, Lehman T, Runnells G, Carroll A, Carter W, Barnhart S, Rasheed AA, Greene G, Johnson DE, Ambrosone CB, Kadlubar FF, Lang NP.

Cancer Epidemiol Biomarkers Prev. 2005 May; 14(5):1257-61.


Fc(gamma)RIIIa and Fc(gamma)RIIa polymorphisms do not predict response to rituximab in B-cell chronic lymphatic leukemia

Farag, S.S., Flinn, I.W., Modali, R., Lehman, T.A., Byrd, J.C.

Blood 103: 1472-1474, 2004.


Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes

Kamel, F., Umbach, D.M., Lehman, T.A., Park, L.P., Munsat, T.L., Shefner, J.M., Sandler, D.P., Hu, H., Taylor J.A.

Environ Health Perspect. 111: 1335-9, 2003.


The ras family of oncogenes in development and progression of lung cancer. Screening of mutations by polymerase chain reaction-based ligase chain reaction

Martinez, A., Lehman, T.A. Modali, R., Mulshine, J.L.

Methods Mol Med. 74:187-200, 2003.


Manganese superoxide dismutase (MnSOD) polymorphism, alpha-tocopherol supplementation and prostate cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study (Finland)

Woodson, K., Tangrea, J.A., Lehman, T.A., Modali, R., Taylor, K.M., Snyder, K., Taylor, P.R., Virtamo, J., Albanes, D.

Cancer Causes Control. 14: 513-518, 2003.


UCN-01 induces cytotoxicity toward human CLL cells through a p53 independent mechanism

Byrd, J.C., Shinn, C., Willis, C.R., Flinn, I.W., Lehman, T., Sausville, E., Lucas, D., Grever, M.R.

Exp. Hematol. 29 (6) 703-708, 2001.


Collection of buccal cell DNA in seventh-grade children using water and a toothbrush

London, S., Xia, J., Lehman, T., Yang, J.H., Granada, E., Chunhong, L., Dubeau, L, Li, T., David-Beabes, G., Li, Y.

Cancer Epidemiology, Biomarkers and Prevention 10: 1227-1230, 2001.


Elevated frequency and functional activity of a specific germ-line p53 intron mutation in familial breast cancer

Lehman, T.A., Haffty, B.G., Carbone, C.J., Bishop, L.R., Gumbs, A.A., Krishnan, S., Shields, P.G., Modali, R., Turner, B.C.

Cancer Res. 60:1062-1069, 2000.


Mutational activation of K-ras in nonneoplastic exocrine pancreatic lesions in relation to cigarette smoking status

Berger, D.H., Chang, H., Wood, M., Huang, L., Heath, C.W., Lehman, T., Ruggeri, B.A.

Cancer 85: 326-329, 1999.


BRCA1 mutations in African Americans

Panguluri R C; Brody L C; Modali R; Utley K; Adams-Campbell L; Day A A; Whitfield-Broome C; Dunston G M.

Human genetics 1999; 105(1-2):28-31.


Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53

Byrd, J.C., Shinn, C., Waselenko, J.K., Fuchs, E.J., Lehman, T.A., Nguyen, P.L., Flinn, I.W., Diehl, L.F., Sausville, E., Grever, M.R.

Blood 92:3804-16, 1998.


Myeloperoxidase genetic polymorphism and lung cancer risk

London, S.J., Lehman, T.A., and Taylor, J.A.

Cancer Res. 57: 5001-5003, 1997.


High frequency of K-ras mutations in bronchial alveolar lavage fluid of patients at high risk for second primary lung cancer

Scott, F., Modali, R., Lehman, T.A., Seddon, M., Kelly, K., Dempsey, E.C., Wilson, V., Tockman, M.S., and Mulshine, J.L.

Clin. Cancer Res. 3: 479-482, 1997.


p53 expression and HPV in proliferative verrucous leukoplakia

Gopalakrishnan, R., Weghorst, C.M., Lehman, T.A., Bijur, G., Sabourin, C.L.K., Mallery, S.R., and Stoner, G.D.

Oral Surgery, Oral Med., Oral Path., Oral Rad., and Endodontics. 83: 471-477, 1997.


Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters

Caloca, M.J., Fernandez, N., Lewin, N.E., Ching, D., Modali, R., Blumburg, P.M., Kazanietz, M.G.

J. Biol. Chem. 272: 26488-26496, 1997.


Chromosomal changes and progressive tumorigenesis of human bronchial epithelial cell lines

Ohnuki, Y., Reddel, R., Bates, S.E., Lehman, T.A., et al.

Cancer Genet. Cytogenet. 92: 99-110, 1996.


Detection of K-ras oncogene mutations by polymerase chain reaction-based ligase chain reaction

Lehman, T.A., Scott, F., Seddon, M., Kelly, K., Dempsey, E.C., Wilson, V.L., Mulshine, J.L., and Modali, R.

Anal. Biochem. 239: 153-159, 1996.


Oncogenes and tumor suppressor genes in human carcinogenesis

Harris, C., Pfeifer, A., Lehman, T., Weston, A., Gerwin, B. and Lechner, J.

Cancer Res. Clin. Oncol.


Interaction of human cytomegalovirus with p53: possible role in coronary restenosis

Speir, E., Huang, E.S., Modali, R., Leon, M.B.

Scand. J. Infect. Dis. Suppl. 99: 78-81, 1995.


Evidence suggesting a causal role of human cytomegalovirus in coronary restinosis: interaction with the tumor suppressor gene p53

Speir, E., Modali, R., Leon, M., Shawl, F., Guzman, R., Finkel, T., Huang, E. S., Griner, J., Choi, B., and Epstein, S. E.

Science 265: 391-394, 1994.


Mutational spectra of protooncogenes and tumor suppressor genes: clues to predict cancer etiology

Lehman, T. A. and Harris, C. C.

IARC Monograph. Vol. 125, Lyon, France, 1994, pp. 399-412.


Mutational spectrum of the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

Lehman, T. A., Greenblatt, M., Bennett, W. P. and Harris, C. C.

Drug Metabol. Rev. 26: 221-235, 1994.


p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers

Hollstein, M., Marion, M.-J., Lehman, T., Welsh, J., Harris, C. C., Kusters, I., and Montesano, R.

Carcinogenesis 15: 1-3, 1994.


p53 mutations in human immortalized epithelial cell lines

Lehman, T.A., Modali, R., Stanek, J., Welsh, J., Bennett W. P., Stampfer, M., Boukamp, P., Fusenig, N., Rogan, E. M., Reddel, R. R. and Harris, C.C.

Carcinogenesis 14:833-839, 1993.


Correlation of p53 mutations with epidermal growth factor receptor overexpression and absence of mdm2 amplification in human esophageal carcinomas

Esteve, A., Lehman, T., Jiang, W., Weinstein, I. B., Harris, C. C., Ruol, A., Peracchia, A., Montesano, R. and Hollstein, M.

Mol. Carcinog. 8: 306-311, 1993.


p53 and Kirsten-ras mutations in human mesothelioma cell lines

Metcalf, R. A., Welsh, J. A., Bennett, W.P., Lehman, T. A., Pelin, K., Linnainmaa, K., Tammilehto, L., Mattson, K., Gerwin, B. I., and Harris, C. C.

Cancer Res. 52:2610-2615, 1992.


Growth suppression mediated by transfection of p53 in Hut292DM human lung cancer cells expressing endogenous wild-type p53 protein

Cajot, J.-F., Anderson, M. J., Lehman, T. A., Shapiro, H., Briggs, A. A. and Stanbridge, E. J.

Cancer Res. 52:6956-6960, 1992.


Oncogene and tumor suppressor gene involvement in human lung carcinogenesis

Lehman, T. A. and Harris, C. C.

Transformation of Human Epithelial Cells: Molecular and Oncogenetic Mechanisms, CRC Press, Florida, 1992, pp. 235-259.


Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor type 1

Gerwin, B.I., Spillare, E., Forrester, K., Lehman, T.A., Kispert, J., Welsh, J.A., Pfeifer, A.M.A., Lechner, J.F., Baker, S.J., Vogelstein, B., and Harris, C.C.

Proc. Natl. Acad. Sci. USA. 89: 2759-2763, 1992.


Oncogenes and tumor suppressor genes involved in human lung carcinogenesis

Harris, C. C., Bennett, W. P., Gerwin, B. I., Iman, D. S., Lehman, T. A., Metcalf, R. A., Pfeifer, A. M. A., Reddel, R. R., Sugimura, H. and Weston, A.

In Brugge, J., Curran, T., Harlow, E. and McCormick, F. (Eds.): Origins of Human Cancer, Cold Spring Harbor Laboratory Press, New York, 1991, pp. 739-744.


Oncogenes and tumor suppressor genes in human lung carcinogenesis

Lehman, T. A., Pfiefer, A. M. A., Metcalf, R. A., Bennett, W. P., Weston, A., Gerwin, B. I., and Harris, C. C.

In: Waxman, S. (Ed.) Second Volume on Differentiation Therapy. Raven Press, New York, 1991, pp. 87-98.


p53 mutations, ras mutations and p53-heat shock 70 protein complexes in human lung cell lines

Lehman, T. A., Bennett, W. P., Metcalf, R. A., Reddel, R., Welsh, J. A., Ecker, J., Modali, R. V., Ullrich, S., Romano, J. W., Appella, E., Testa, J. R., Gerwin, B. I., Harris, C. C.

Cancer Res. 51: 4090-4096, 1991.


Oncogenes and tumor suppressor genes

Lehman, T. A., Reddel, R. R., Pfeifer, A. M. A., Spillare, E., Kaighn, M. E., Weston, A., Gerwin, B. I. and Harris, C. C.

Environ. Health Perspect. 93: 133-144, 1991.


Neoplastic transformation and suppression of transformation of human bronchial epithelial cells in vitro

Lehman, T. A., and Harris, C. C.

In Rhim, J.S. and Dritschilo A. (Eds.): Neoplastic Transformation in Human Cell Culture, The Humana Press, Inc., New Jersey. 1991, pp.251-258.


Oncogenes and tumor suppressor genes involved in human lung carcinogenesis

Harris, C. C., Reddel, R., Modali, R., Lehman, T. A., Iman, D., McMenamin, M., Sugimura, H., Weston, A. and Pfeifer, A.

In Sutherland, B. M. and Woodhead, A. D. (Eds.): DNA Damage and Repair in Human Tissues, New York, Plenum Press, 1990, pp. 363-380.


Oncogenes and tumor suppressor genes in human lung carcinogenesis

Harris, C. C., Reddel, R., Pfeifer, A., Amstad, P., Mark, G., Weston, A., Modali, R., Iman, D., McMenamin, M., Kaighn, E., Gabrielson, E., Jones, R. and Trump, B. F.

In Harris, C. C. and Liotta, L. (Eds.): Genetic Mechanisms in Carcinogenesis and Tumor Progression, New York, Wiley-Liss, 1990, pp 127-152.


Human debrisoquine hydroxylase gene polymorphisms in cancer patients and controls

Sugimura, H., Caporaso, N.E., Shaw, G.L., Modali, R.V., Gonzalez, F.J., Hoover, R.N., Resau, J.H., Trump, B.F., Weston, A. and Harris, C.C.

Carcinogenesis 11: 1527-1530, 1990.


Association of rare alleles of the Ha-ras-1 locus with lung cancer

Sugimura, H., Caporaso, N. E., Hoover, R. N., Modali, R., Resau, J., Trump, B. F., Lonergan, J. A., Krontiris, T. G., Mann, D. L., Weston, A. and Harris, C. C.

Cancer Res. 50: 1857-1862, 1990.


Molecular dosimetry, genetic susceptibility and cancer risk

Weston, A., Sugimura, H., Modali, R., Bowman, E.D., Caporaso, N.E., Manchester, D. K., Shields, P. G., Poirier, M. C. and Harris, C. C.

In Volans, G. N., Sims, J., Sullivan, F.M. and Turner, P. (Eds.): Basic Science Proceedings of the V International Congress of Toxicology, Philadelphia, Taylor and Francis, Ltd., 1990, pp. 263-279.


p53 gene mutations occur in diverse human tumor types

Nigro, J. M., Baker, S. J., Preisinger, A. C., Jessup, J. M., Hostetter, R., Cleary, K., Bigner, S. H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Weston, A., Modali, R., Harris, C. C. and Vogelstein, B.

Nature 342: 705-708, 1989.


Differential DNA sequence deletions from chromosomes 3, 11, 13 and 17 in squamous cell carcinoma, large cell carcinoma and adenocarcinoma of the human lung

Weston, A., Willey, J. C., Modali, R., Sugimura, H., McDowell, E., Resau, J., Light, B., Haugen, A., Mann, D. L., Trump, B. F. and Harris, C. C.

Proc. Natl. Acad. Sci. USA 86: 5099-5103, 1989.


Development of neoplastic phenotype following transfection of HNF cell with sarcoma DNA

Kumari, H. L., Shuler, C. F., Lehman, T., Ferrone, S. and Milo, G. E.

Carcinogenesis 10: 401-404, 1989.


Comparative stages of expression of human squamous carcinoma cells

Milo, G. E., Yohn, J., Schuller, D., Noyes, I. and Lehman, T.

J. Invest. Dermatol. 92: 848-853, 1989.


Metabolism of and DNA adduct formation by benzo[a]pyrene in human skin epithelial cells in vitro pretreated with cytochrome P450 modulators

Lehman, T., Kurian, P. and Milo, G. E.

Cancer Biochem. Biophys. 10: 345-352, 1989.


Benzo[a]pyrene diol epoxide I modification of DNA in human skin xenografts

Yohn, J., Lehman, T. A., Kurian, P., Ribovich, M. and Milo, G.E.

J. Invest. Dermatol. 91: 363-368, 1988.


DNA binding and adduct formation of 4,4-methylene-bis(2-chloroainline) (MOCA) in explant cultures of human and dog bladder

Stoner, G. D., Shivapurkar, N. M., Schut, H. A. J. and Lehman, T.

Cancer Lett. 39: 237-240, 1988.


Cocarcinogenicity of saccharin and N-alkyl-nitrosoureas in cultured diploid human fibroblasts

Milo, G. E., Oldham, J. W., Noyes, I., Lehman, T. A., Kumari, H. L., West, R. W. and Kadlubar, F. F.

J. Toxicol. Envirn. Health 24: 413-421, 1988.


Transforming DNA sequences of human hepatocellular carcinomas, their distribution and relationship with hepatitis B virus sequence in human hepatomas

Yang, S. S., Modali, R., Park, J. B. and Taub, J. V.

Leukemia 2: 102s-113s, 1988.


DNA binding of 4,4′-methylene-bis(2-chloroainline) (MOCA) in explant cultures of human and dog bladder

Shivapurkar, N., Lehman, T., Schut, H. A. J. and Stoner, G. D.

Cancer Lett. 38: 41-48, 1987.


Establishment and chemical and transformation of human skin epithelial cells in vitro

Lehman, T., Noyes, I. and Milo, G. E.

J. Tissue Culture Methods 10: 197-203, 1986.


Specificity of aflatoxin B1 binding on human proto-oncogene nucleotide sequence

Modali, R. and Yang, S. S.

Prog. Clin. Biol. Res. 207: 147-158, 1986.


Dose dependency of aflatoxin B1 binding on human high molecular weight DNA in the activation of proto-oncogenes

Yang, S. S., Taub, J. V., Modali, R., Vieira, W., Yasei, P. and Yang, G. C.

Environ. Health Perspect. 62: 231-238, 1985.


Formation of aflatoxin B1-DNA adducts in normal rat and hepatoma tissue culture cells and in human livers from fetal, Reye’s syndrome and hepatocellular carcinoma

Yang, S. S., Modali, R. and Yang, G. C.

Advances in Gene Technology: Human Genetic Disorders. In: Ahmad, F., Black, S., Schultz, J., Scott, W. A. and Whelan, W. J. (Eds.), ICSU Press, Florida, pp. 272-273, 1984.


Cloning of the rat endogenous helper leukemia virus DNA sequence and expression of the helper activity encoded by the cloned DNA sequence in normal rat kidney cells by micro-injection

Yang, S. S., Modali, R. and Murphy, E., Jr.

Eucaryotic Cell Culture: Basic and Application. Advances in Experimental Medicine and Biology, 172. In: Acton, R. and Lynn, J. D. (Eds.), Plenum Press, New York, pp. 295-319, 1984.


An analysis of the genomic complexity of the cloned wild rat endogenous retrovirus (WR-RaLV) DNA

Yang, S. S. and Modali, R.

Leukemia Rev. 1: 310-312, 1983.


Molecular cloning of the rat leukemia-helper virus DNA sequences and functional analysis of some restricted DNA fragments

Yang, S. S., Taub, J., Modali, R. and Gardner, M.

Advances in Comparative Leukemia Research 1981. In: Yohn, D. S. and Blakeslee, J. R. (Eds.), Elsevier/North-Holland Biomedical Press, pp. 351-352, 1982.


Molecular cloning of the endogenous rat C-type helper virus DNA sequence: Structural organization and functional analysis of some restricted DNA fragments

Yang, S. S., Modali, R., Wu, R. and Gardner, M.

J. Gen. Virol. 63: 25-36, 1982.


Biological activity of cloned rat endogenous C-type viral DNA transferred by microinjection

Yang, S. S., Taub, J., Modali, R., Brown, D. and Murphy, E., Jr.

J. Gen. Virol. 63: 37-43, 1982.


Genomic complexity and molecularly cloning of a proviral DNA specific for a feral rat endogenous C-type virus, originated from a 3-methyl cholanthrene induced fibrosarcoma

Yang, S. S. and Modali, R.

Progress in Nucleic Acid Research and Molecular Biology, Vol. 29, In: Cohn, W. (Ed.), Academic Press, New York, pp. 145-149, 1982.