Respiratory
Our scientists can compare the effects of your test compounds on the constriction or relaxation of animal and human airways (bronchi). We can also assess species differences in airway inflammation, using our ex vivo precision-cut lung slice (PCLS) and parenchymal explant models.
Cardiovascular
Many drugs have been shown to have a direct effect on cardiac function, but cardiac safety data generated in animals do not always mimic the human drug response. Our scientists can provide species comparison assays to determine whether your cardiac safety data will translate to humans.
Genitourinary
Our scientists can provide studies in human and rat uterine tissue to identify species differences in uterine contractility. Animal tests measuring uterine contractility may not fully reflect the human response.
