Precision-Cut Lung Slices (PCLS)
Precision-cut lung slices (PCLS) are increasingly in demand for the testing of novel drugs and biochemicals. By retaining the structural and functional integrity of human or animal lungs, PCLS combines throughput with relevance, offering a phenotypically accurate model for drug discovery.
- Tissues from healthy, animal, COPD, or asthma donors can be obtained
- Dozens of slices can be created per donor and cultured for up to 7 days
- Biomarker release, structural integrity, tissue viability, and inflammation can be evaluated
Image: Histochemical analysis of a lung slice used in our PCLS studies.
Precision-cut lung slice (PCLS) culture
Assess whether your test article has anti-inflammatory effects in precision-cut lung slices using Fluticasone or Roflumilast as a reference compound.