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Pulmonary Artery Tone 

The pulmonary arteries carry deoxygenated blood to the lungs and are essential for healthy respiratory function. Our organ bath model can measure changes in the vascular tone of these arteries in response to your test articles. This diverse test system can estimate a range of function endpoints ex vivo.

  • Vasoconstriction and vasodilatation can be measured
  • Several drug targets and reference compounds are available 
  • Safety assessment can be conducted in accordance with GLP regulations
  • IC50 and pA2 can be determined

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Image: Isolated pulmonary sections in a Petri dish. 

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Pulmonary artery tone assay

Determine whether your test article causes changes in the vascular tone of human pulmonary arteries.