Our selection of human cardiovascular intact fresh tissue models offers a unique insight into the likely effects of your test article in the clinic. Our scientists create customized protocols that answer your specific questions about the effects of test drugs on human cardiac or vascular function using fresh intact blood vessels or cardiac muscle donated via our extensive network of clinical partners from across the UK and USA. The functional tissues are transported rapidly to our pharmacology labs in the USA or UK where our experience scientists are on hand to conduct ex vivo experiments. We can also conduct comparative studies in other preclinical species to explore species differences using the same blood vessels or cardiac tissues.
For regulatory safety pharmacology studies in accordance with ICH S7A, we offer the ability to conduct studies in accordance with Good Laboratory Practice (GLP) and are the only GLP CRO using human fresh, functional, intact tissues.