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Urethra Contraction

The urethra is essential for the excretion of urine and semen. Any changes to the urethra, such as prostate hypertrophy, can affect the passage of these substances. We can assess the effects of your test article on the contraction (or relaxation) of the human urethra using our organ bath system.

Adrenoceptor-phenylephrine model
Assess whether your test article causes contraction of the urethra, with phenylephrine as a reference compound.