Meet us next:   BIO International Convention 2025 – 4 September  ●  ELRIG – Drug Discovery in Scotland 2025 – 17 September  ●  The Cell & Gene Meeting on the Mesa 2025 – 6-8 October (in person) & 9-10 October (virtual)  ●  ELRIG – Drug Discovery – 21-22 October  ●  more on our events calendar

Gastrointestinal Permeability Assays

Our permeability studies use human gastrointestinal (GI) tissues which have a phenotypically accurate balance of drug-metabolizing enzymes and transporters. A typical experiment involves the application of a drug to the apical surface of the tissue, followed by periodic sampling of the Ussing chambers to measure the passage of drugs and any metabolites.

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  • Up to 8 test conditions available per donor 
  • Healthy large intestine tissues used
  • Provides the closest method to testing your drug in the clinic
  • Option to conduct studies in accordance with GLP

Ussing chamber close up
Close-up of one of our scientists operating an Ussing chamber in our Glasgow laboratory.

 

Gastrointestinal permeability assays in our catalog

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Heathy GI permeability model

This model uses gut biopsies from healthy donors to assess the gastrointestinal permeability of your test articles.

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