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Drug Discovery Assay Catalog

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Total assays available:

Vasoconstriction in Human Coronary Arteries (5-HT Receptor – 5-HT)

Reference number: B003

Assay type: Blood Vessels
Tissue: Human Coronary Artery (Healthy)
Target: 5-HT receptor
Control Compound: 5-HT
Study Type: Wire Myography
Functional Endpoint: Vasoconstriction

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Vasoconstriction in Human Coronary Arteries (Opioid and Opioid-Like Receptors)

Reference number: B004

Assay type: Blood Vessels
Tissue: Human Coronary Artery (Healthy)
Target: Opioid & opioid-like receptors
Control Compound: Mephedrone
Study Type: Wire Myography
Functional Endpoint: Vasoconstriction

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Vasoconstriction in Human Coronary Arteries (Angiotensin Receptor)

Reference number: B007

Assay type: Blood Vessels
Tissue: Human Coronary Artery (Healthy)
Target: Angiotensin receptor
Control Compound: Angiotensin II
Study Type: Organ bath
Functional Endpoint: Vasoconstriction

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Vasoconstriction in Human Coronary Arteries (Vasopressin & Oxytocin Receptors)

Reference number: B008

Assay type: Blood Vessels
Tissue: Human Coronary Artery (Healthy)
Target: Vasopressin & oxytocin receptors
Control Compound: 8-arginine vasopressin
Study Type: Organ bath
Functional Endpoint: Vasoconstriction

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Vasodilatation in Human Chorionic Plate Arteries (PDE5)

Reference number: B009

Assay type: Blood Vessels
Tissue: Human Chorionic Plate Arteries (Pre-Eclamptic)
Target: PDE5
Control Compound: Sildenafil
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Chorionic Plate Arteries (Bradykinin receptor)

Reference number: B010

Assay type: Blood Vessels
Tissue: Human Chorionic Plate Arteries (Healthy)
Target: Bradykinin receptor
Control Compound: Bradykinin
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Pre-Eclamptic Chorionic Plate Arteries (PDE5)

Reference number: B011

Assay type: Blood Vessels
Tissue: Human Chorionic Plate Arteries (Pre-Eclamptic)
Target: PDE5
Control Compound: Sildenafil
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Pre-Eclamptic Chorionic Plate Arteries (Bradykinin Receptor)

Reference number: B012

Assay type: Blood Vessels
Tissue: Human Chorionic Plate Arteries (Pre-Eclamptic)
Target: Bradykinin receptor
Control Compound: Bradykinin
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Subcutaneous Resistance Arteries (Acetylcholine Receptor)

Reference number: B016

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Healthy)
Target: Acetylcholine receptor
Control Compound: Acetylcholine
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Subcutaneous Resistance Arteries (Vasopressin & Oxytocin Receptors)

Reference number: B017

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Healthy)
Target: Vasopressin & oxytocin receptors
Control Compound: Desmopressin
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Subcutaneous Resistance Arteries (Nitric Oxide Donor)

Reference number: B019

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Healthy)
Target: Nitric oxide donor
Control Compound: SNP
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasoconstriction in Human Subcutaneous Resistance Arteries (Adrenoceptor)

Reference number: B020

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Healthy)
Target: Adrenoceptor
Control Compound: Phenylephrine
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasoconstriction in Human Subcutaneous Resistance Arteries (Prostanoid Receptor)

Reference number: B021

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Healthy)
Target: Prostanoid receptor
Control Compound: U46619
Study Type: Wire Myography
Functional Endpoint: Vasoconstriction

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Vasodilatation in Ischaemic Human Subcutaneous Resistance Arteries (Bradykinin Receptor)

Reference number: B022

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Ischaemic)
Target: Bradykinin receptor
Control Compound: Bradykinin
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasoconstriction in Human Saphenous Vein (5-HT Receptor)

Reference number: B023

Assay type: Blood Vessels
Tissue: Human Saphenous Vein (Healthy)
Target: 5-HT receptor
Control Compound: Sumatriptan
Study Type: Wire Myography
Functional Endpoint: Vasoconstriction

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Vasoconstriction in Human Coronary Arteries (5-HT Receptor – Sumatriptan)

Reference number: B028

Assay type: Blood Vessels
Tissue: Human Coronary Artery (Healthy)
Target: 5-HT receptor
Control Compound: Sumatriptan
Study Type: Wire Myography
Functional Endpoint: Vasoconstriction

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Vasoconstriction in Denuded Human Coronary Arteries (5-HT Receptor)

Reference number: B030

Assay type: Blood Vessels
Tissue: Human Coronary Artery (Healthy – Denuded)
Target: 5-HT receptor
Control Compound: 5-HT
Study Type: Organ bath
Functional Endpoint: Vasoconstriction

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Vasodilatation in Human Subcutaneous Resistance Arteries (PDE3 Receptor)

Reference number: B034

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Healthy)
Target: PDE3
Control Compound: Milrinone
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Subcutaneous Resistance Arteries (Bradykinin Receptor)

Reference number: B035

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Healthy)
Target: Bradykinin receptor
Control Compound: Bradykinin
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasoconstriction in Atherosclerotic Human Subcutaneous Resistance Arteries (Angiotensin Receptor)

Reference number: B037

Assay type: Blood Vessels
Tissue: Human Resistance Artery (Atherosclerotic)
Target: Angiotensin receptor
Control Compound: PDA-angiotensin 1
Study Type: Wire Myography
Functional Endpoint: Vasoconstriction

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Vasodilatation in Ischaemic Human Subcutaneous Resistance Arteries (Nitric Oxide Donor)

Reference number: B038

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Ischaemic)
Target: Nitric oxide donor
Control Compound: SNP
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Skeletal Muscle Arteries (Acetycholine Receptor)

Reference number: B039

Assay type: Blood Vessels
Tissue: Human Skeletal Muscle Artery (Healthy)
Target: Acetylcholine receptor
Control Compound: Acetylcholine
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Vasodilatation in Human Skeletal Muscle Arteries (Nitric Oxide Donor)

Reference number: B040

Assay type: Blood Vessels
Tissue: Human Skeletal Muscle Artery (Healthy)
Target: Nitric oxide donor
Control Compound: SNP
Study Type: Wire Myography
Functional Endpoint: Vasodilatation

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Contractile Force in Electrically Stimulated Human Atrial Pectinate Muscle (Adrenoceptors – Isoprenaline)

Reference number: B043

Assay type: Cardiac Muscle
Tissue: Human Atrial Pectinate Muscle (Healthy)
Target: Adrenoceptor
Control Compound: Isoprenaline
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Contractile Force in Electrically Stimulated Human Ventricular Trabeculae Muscle (5-HT Receptor)

Reference number: B047

Assay type: Cardiac Muscle
Tissue: Human Ventricular Trabeculae Muscle (Healthy)
Target: 5-HT receptor
Control Compound: 5-HT
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Contractile Force in Electrically Stimulated Human Atrial Pectinate Muscle (5-HT Receptor)

Reference number: B048

Assay type: Cardiac Muscle
Tissue: Human Atrial Pectinate Muscle (Healthy)
Target: 5-HT receptor
Control Compound: 5-HT
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Contractile Force in Electrically Stimulated Human Atrial Pectinate Muscle (Adrenoceptors – Salbutamol)

Reference number: B049

Assay type: Cardiac Muscle
Tissue: Human Atrial Pectinate Muscle (Healthy)
Target: Adrenoceptor
Control Compound: Salbutamol
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Contractile Force in Electrically Stimulated Human Atrial Pectinate Muscle (PDE3 Receptor)

Reference number: B050

Assay type: Cardiac Muscle
Tissue: Human Atrial Pectinate Muscle (Healthy)
Target: PDE3
Control Compound: Milrinone
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Bronchodilatation in Secondary Healthy Human Airways (Adrenoceptor – Isoprenaline)

Reference number: B052

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Healthy)
Target: Adrenoceptor
Control Compound: Isoprenaline
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Bronchoconstriction in Secondary Asthmatic Human Airways (Acetylcholine Receptor)

Reference number: B053

Assay type: Respiratory
Tissue: Human Secondary Airways (Asthmatic)
Target: Acetylcholine receptor
Control Compound: Carbachol
Study Type: Organ bath
Functional Endpoint: Bronchoconstriction

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Bronchodilatation in Secondary Asthmatic Human Airways (Adrenoceptor)

Reference number: B054

Assay type: Respiratory
Tissue: Human Secondary Airways (Asthmatic)
Target: Adrenoceptor
Control Compound: Salbutamol
Study Type: Organ bath
Functional Endpoint: Bronchodilatation

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Bronchoconstriction in Tertiary or Lower Healthy Human Airways (Prostanoid Receptor)

Reference number: B055

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Healthy)
Target: Prostanoid receptor
Control Compound: U46619
Study Type: Wire Myography
Functional Endpoint: Bronchoconstriction

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Bronchodilatation in Tertiary or Lower Healthy Human Airways (Adrenoceptor – Salbutamol)

Reference number: B056

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Healthy)
Target: Adrenoceptor
Control Compound: Salbutamol
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Bronchoconstriction in Tertiary or Lower Healthy Human Airways (Acetylcholine Receptor)

Reference number: B057

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Healthy)
Target: Acetylcholine receptor
Control Compound: Acetylcholine
Study Type: Wire Myography
Functional Endpoint: Bronchoconstriction

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Bronchodilatation in Tertiary or Lower Healthy Human Airways (Adrenoceptor – Isoprenaline)

Reference number: B058

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Healthy)
Target: Adrenoceptor
Control Compound: Isoprenaline
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Bronchodilatation in Tertiary or Lower Airways COPD (Adrenoceptor)

Reference number: B059

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (COPD)
Target: Adrenoceptor
Control Compound: Isoprenaline
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Bronchoconstriction in Denuded Secondary Healthy Human Airways (Acetylcholine Receptor)

Reference number: B060

Assay type: Respiratory
Tissue: Human Secondary Airways (Healthy – Denuded)
Target: Acetylcholine receptor
Control Compound: Carbachol
Study Type: Organ bath
Functional Endpoint: Bronchoconstriction

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Bronchoconstriction in Denuded Secondary Healthy Human Airways (Histamine Receptor)

Reference number: B061

Assay type: Respiratory
Tissue: Human Secondary Airways (Healthy – Denuded)
Target: Histamine receptor
Control Compound: Histamine
Study Type: Organ bath
Functional Endpoint: Bronchoconstriction

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Bronchodilatation in Tertiary or Lower Human Airways (Adrenoceptors – Formoterol)

Reference number: B065

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Healthy)
Target: Adrenoceptor
Control Compound: Formoterol
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Bronchodilatation in Tertiary or Lower Human Airways (Adrenoceptors – Salbutamol)

Reference number: B066

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Healthy)
Target:  
Control Compound: Salbutamol
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Bronchodilatation in Tertiary or Lower Asthmatic Human Airways (Adrenoceptor – Formoterol)

Reference number: B067

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Asthmatic)
Target: Adrenoceptor
Control Compound: Formoterol
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Bronchodilatation in Tertiary or Lower Asthmatic Human Airways (Adrenoceptor – Salbutamol)

Reference number: B068

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Asthmatic)
Target: Adrenoceptor
Control Compound: Salbutamol
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Bronchodilatation in Tertiary or Lower Asthmatic Human Airways (Adrenoceptor – Salmeterol)

Reference number: B069

Assay type: Respiratory
Tissue: Human Tertiary Or Lower Airways (Asthmatic)
Target: Adrenoceptor
Control Compound: Salmeterol
Study Type: Wire Myography
Functional Endpoint: Bronchodilatation

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Relaxation in Human Bladder (Adrenoceptor – Isoproterenol)

Reference number: B070

Assay type: GU
Tissue: Human Bladder (Healthy)
Target: Adrenoceptor
Control Compound: Isoproterenol
Study Type: Organ bath
Functional Endpoint: Relaxation

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Relaxation in Human Ureter (Adrenoceptor – Isoprenaline)

Reference number: B071

Assay type: GU
Tissue: Human Ureter (Healthy)
Target: Adrenoceptor
Control Compound: Isoprenaline
Study Type: Organ bath
Functional Endpoint: Relaxation

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Contraction in Human Urethra (Adrenoceptor – Phenylephrine)

Reference number: B072

Assay type: GU
Tissue: Human Urethra (Healthy)
Target: Adrenoceptor
Control Compound: Phenylephrine
Study Type: Organ bath
Functional Endpoint: Contractility

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Contraction in Human Uterus (Vasopressin & Oxytocin Receptor – Oxytocin)

Reference number: B078

Assay type: GU
Tissue: Human Uterus (Healthy)
Target: Vasopressin & oxytocin receptors
Control Compound: Oxytocin
Study Type: Organ bath
Functional Endpoint: Contractility

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Contraction in Human Uterus (Vasopressin & Oxytocin Receptor – Vasopressin)

Reference number: B079

Assay type: GU
Tissue: Human Uterus (Healthy)
Target: Vasopressin & oxytocin receptors
Control Compound: Vasopressin
Study Type: Organ bath
Functional Endpoint: Contractility

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Relaxation in Human Uterus (Nitric Oxide Donor)

Reference number: B081

Assay type: GU
Tissue: Human Uterus (Healthy)
Target: Nitric oxide donor
Control Compound: SNP
Study Type: Organ bath
Functional Endpoint: Relaxation

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Relaxation in Human Uterus (Adrenoceptor – Isoprenaline)

Reference number: B082

Assay type: GU
Tissue: Human Uterus (Healthy)
Target: Adrenoceptor
Control Compound: Isoprenaline
Study Type: Organ bath
Functional Endpoint: Relaxation

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Relaxation in Human Uterus (Calcium Channels)

Reference number: B083

Assay type: GU
Tissue: Human Uterus (Healthy)
Target: Calcium channels
Control Compound: Isradipine
Study Type: Organ bath
Functional Endpoint: Relaxation

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Contractile Force in Electrically Stimulated Human Colon (Acetylcholine Esterase)

Reference number: B086

Assay type: GI Tract
Tissue: Human Stomach (Healthy)
Target: Acetylcholine esterase
Control Compound: Galantamine
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Contractile Force in Electrically Stimulated Human Colon (Opioid & Opioid-Like Receptors)

Reference number: B087

Assay type: GI Tract
Tissue: Human Colon
Target: Opioid & opioid-like receptors
Control Compound: Meptazinol
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Contractile Force in Electrically Stimulated Human Stomach (Motilin Receptor)

Reference number: B092

Assay type: GI Tract
Tissue: Human Stomach (Healthy)
Target: Motilin receptor
Control Compound: Erythromycin
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Permeability in Healthy Human Gastrointestinal Mucosa

Reference number: B093

Assay type: GI Tract
Tissue: Human Gastrointestinal Mucosa
Target: N/A
Control Compound: Multiple
Study Type: Ussing chamber
Functional Endpoint: Permeability

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Ion Channel Function in Isolated Healthy Human Gastrointestinal Mucosa (Chloride Channels)

Reference number: B094

Assay type: GI Tract
Tissue: Human Gastrointestinal Mucosa (Healthy)
Target: Chloride channels
Control Compound: Cholera toxin
Study Type: Ussing chamber
Functional Endpoint: Ion channel function

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Contractile Force in Electrically Stimulated Human Ventricular Trabeculae Muscle (Adrenoceptor)

Reference number: B095

Assay type: Cardiac Muscle
Tissue: Human Ventricular Trabeculae Muscle (Healthy)
Target: Adrenoceptor
Control Compound: Isoprenaline
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Contractile Force in Eletrically Stimulated Human Ventricular Trabeculae Muscle (Acetylcholine Receptor)

Reference number: B096

Assay type: Cardiac Muscle
Tissue: Human Ventricular Trabeculae Muscle (Healthy)
Target: Acetylcholine receptor
Control Compound: Acetylcholine
Study Type: EFS organ bath
Functional Endpoint: Contractility

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Vasoconstriction in Human Subcutaneous Resistance Arteries (5-HT Receptor)

Reference number: B097

Assay type: Blood Vessels
Tissue: Human Subcutaneous Resistance Artery (Healthy)
Target: 5-HT receptor
Control Compound: 5-HT
Study Type: Wire Myography
Functional Endpoint: Vasoconstriction

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Bronchodilatation in Healthy Human Secondary Airways (VIP & PACAP Receptors)

Reference number: B098

Assay type: Respiratory
Tissue: Human Secondary Airways (Healthy)
Target: VIP & PACAP
Control Compound: Vasoactive Intestinal Polypeptide (VIP)
Study Type: Organ bath
Functional Endpoint: Bronchodilatation

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Bronchoconstriction in Healthy Human Tertiary or Lower Airways (Lopoxin, Oxoeiconsanoid and Resolvin E1)

Reference number: B099

Assay type: Respiratory
Tissue: Human Secondary Airways (Healthy)
Target: VIP & PACAP
Control Compound: Vasoactive Intestinal Polypeptide (VIP)
Study Type: Organ bath
Functional Endpoint: Bronchodilatation

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IBD Culture Study Crohn’s or Ulcerative Colitis (UC)

Reference number: B106

Tissue: Human GI Mucosal Explants (IBD)
Target: p38 MAP Kinase
Control Compound: BIRB796
Study Type: Ex vivo Cultures
Functional Endpoint: Inflammation

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Contraction in Human Bladder (Muscarinic – Carbachol)

Reference number: B107

Assay type: GU
Tissue: Human Bladder (Healthy)
Target: Muscarinic receptors
Control Compound: Carbachol
Study Type: Organ bath
Functional Endpoint: Contractility

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Contraction, Relaxation in Human Bladder Electrically Stimulated

Reference number: B108

Assay type: GU
Tissue: Human Bladder (Healthy)
Target: Muscarinic/ beta-adrenergic receptors/ ion channels
Control Compound: Carbachol/ isoproterenol/ retigabine
Study Type: Organ bath
Functional Endpoint: Modulation of EFS-induced contractions

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Permeability in IBD Human Gastrointestinal Mucosa

Reference number: B109

Assay type: GI Tract
Tissue: Human Diseased (IBD) Gastrointestinal Mucosa
Target: N/A
Control Compound: Multiple
Study Type: Ussing chamber
Functional Endpoint: Permeability

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Pulmonary Artery Tone

Reference number: B110

Assay type: GU / Blood Vessels
Tissue: Human Pulmonary Artery (Healthy) / Human Pulmonary Artery (Healthy – Denuded)
Target: Muscarinic Receptors/ Angiotensin receptor/ Nitric oxide donor/ Endothelin receptor/ Prostacyclin receptor/ Prostaglandin EP2 receptor/ Prostaglandin EP4 receptor/ Beta adrenergic receptor
Control Compound: Acetylcholine/ Angiotensin II/ Sildenafil/ U46619/ Endothelin-1/ Iloprost/ Bosentan/ Wire Myography
Study Type: Organ bath
Functional Endpoint: Contractile force/ Contraction/ Relaxation/ Vasoconstriction/ Vasodilatation

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Skin Inflammation LPS (Acne) (Systemic/Topical)

Reference number: B111

Assay type: Skin
Tissue: Human Skin Biopsies (Healthy)
Target: TLR4/TLR2 Pathway/ Glucocorticoid receptors/ NLRP3 Inflammasome
Control Compound: Betnovate/ Nitric Oxide 
Study Type: Ex vivo cultures
Functional Endpoint: Cytokine release

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Lung PCLS Culture

Reference number: B112

Assay type: Respiratory
Tissue: Human Precision Cut Lung Slice (PCLS)
Target: TLR4/TLR2 Pathway/ Glucocorticoid receptors/ NLRP3 Inflammasome
Control Compound: Fluticasone/ Roflumilast
Study Type: Ex vivo cultures
Functional Endpoint: Cytokine release

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Skin Culture Induced Psoriasis Model (Systemic/Topical)

Reference number: B113

Assay type: Skin
Tissue: Human Skin Biopsies (Healthy)
Target:

Glucocorticoid receptors/ Retinoid receptors/ Th17 Pathway

Control Compound: Retigabine/ Betnovate/ Calcipotriol/ ROR gamma antagonist GSK2981278/ Dovonex (topical calcipotriol)/ Dovobet (topical calcipotriol plus Betamethasone)/ Zorac/ Dermovate/ Phase1/Phase 2 metabolic enzymes
Study Type: Ex vivo cultures
Functional Endpoint: Cytokine release/ Gene Expression

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Relaxation in Human LES

Reference number: B114

Assay type: Gastrointestinal (GI) Tract
Tissue: Human Lower esophageal sphincter
Target: TGR5 receptor
Control Compound: Carbachol/ Isoprenaline
Study Type: Organ bath
Functional Endpoint: Contractile force/ Relaxation

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Contraction in Human LES

Reference number: B115

Assay type: Gastrointestinal (GI) Tract
Tissue: Human Lower esophageal sphincter
Target: TGR5 receptor
Control Compound: Carbachol/ Isoprenaline
Study Type: Organ bath
Functional Endpoint: Contractile force/Contraction

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GI Metabolism

Reference number: B116

Assay type: Gastrointestinal (GI) Tract
Tissue: Human Colon/ Human Gastrointestinal Mucosa (Healthy)
Target: Phase1/Phase 2 metabolic enzymes
Control Compound: Phase1/Phase 2 metabolic enzymes
Study Type: Ussing chamber
Functional Endpoint: Metabolism

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Healthy Skin Culture

Reference number: B117

Assay type: Skin
Tissue: Human Skin Biopsies (Healthy)
Target: Study Dependant
Control Compound: LPS
Study Type: Ex vivo cultures
Functional Endpoint: Inflammation

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Skin Biopsies Atopic Dermatitis (Systemic/Topical)

Reference number: B118

Assay type: Skin
Tissue: Skin Disease Biopsies
Target: Study Dependant
Control Compound: Betamethasone
Study Type: Ex vivo cultures
Functional Endpoint: Inflammation

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Skin Biopsies Atopic Psoraisis (Systemic/Topical)

Reference number: B119

Assay type: Skin
Tissue: Skin Disease Biopsies
Target: Study Dependant
Control Compound: Betamethasone
Study Type: Ex vivo cultures
Functional Endpoint: Inflammation

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Skin Inflammation PHA (Systemic/Topical)

Reference number: B120

Assay type: Skin
Tissue: Human Skin Biopsies (Healthy)
Target: Study Dependant
Control Compound: Betamethasone
Study Type: Ex vivo cultures
Functional Endpoint: Inflammation

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Skin Culture Induced Atopic Dermatitis Model (Systemic/Topical)

Reference number: B121

Assay type: Skin
Tissue: Human Skin Biopsies (Healthy)
Target: TH2 Pathway
Control Compound: Betamethasone
Study Type: Ex vivo cultures
Functional Endpoint: Inflammation

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Mouse IBD Model – Crohn’s or Ulcerative Colitis (UC)

Reference number: B122

Tissue: Murine GI mucosal explants (IBD)
Study Type: Ex vivo cultures
Functional Endpoint: Inflammation

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Contractility of Rat Uterus (Vasopressin & Oxytocin Receptor)

Reference number: B123

Assay type: Genitourinary (GU)
Tissue: Rat uterus (healthy)
Target: Vasopressin & oxytocin receptors
Control Compound: Oxytocin
Study Type: Organ bath
Functional Endpoint: Contractility

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Ex Vivo Skin Explants and Bioengineered 3D Human Skin In Vitro Models

Reference number: B124

Assay type: Skin
Tissue: Human Skin Disease Biopsies, Human Skin (Surgical)
Target: Study dependant
Control Compound: Study dependant
Study Type: 3D Cell Culture
Functional Endpoint: Study dependant

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