Drug Discovery Assay – reference number: B115
| Assay type: | Gastrointestinal (GI) tract |
| Tissue: | Human lower esophageal sphincter |
| Target: | TGR5 receptor |
| Control compound: | Carbachol/ isoprenaline |
| Study type: | Organ bath |
| Functional endpoint: | Contractile force/ contraction |
Figure 1: Cumulative concentration response curve to carbachol in human isolated lower esophageal sphincter muscle strips
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