REPROSKIN™ Full Thickness Human Skin Equivalent
RSK001-FT-6 / RSK001-FT-12 / RSK-MEDIA-001
Brand: Alvetex®
REPROSKIN™ Full Thickness Human Skin Equivalent is designed to provide a physiologically relevant in vitro model for preclinical dermatology research, toxicity testing and mechanistic studies. Each tissue incorporates both epidermal and dermal components, produced using human primary keratinocytes and dermal fibroblasts, and is cultured at an air–liquid interface to support stratified epidermal morphology and barrier function.
Supplied as removable inserts in a deep 6-well plate with accessories, REPROSKIN™ offers researchers a convenient, ready-to-use skin model with defined handling, quality control and safety criteria for reproducible experimental use.
| Product name | Catalog number | Pack size | Price | Price | Price (USD) | Price (GBP) | Price (EUR) |
|---|---|---|---|---|---|---|---|
| REPROSKIN™ Full Thickness Human Skin Equivalent, 1 plate | RSK001-FT-6 | 1 plate | Ask us | $ | £ | € | |
| REPROSKIN™ Full Thickness Human Skin Equivalent, 2 plates | RSK001-FT-12 | 2 plates | Ask us | $ | £ | € |
Overview
REPROSKIN is a bioengineered full-thickness human skin model that combines primary human fibroblasts, primary human keratinocytes and proprietary Alvetex® technology to recreate the structure and function of native human skin. Designed for researchers who need more biologically relevant data than conventional cell culture can provide, REPROSKIN delivers a living, three-dimensional tissue model suitable for efficacy, safety, barrier function and skin biology studies.
Unlike simplified skin models, REPROSKIN allows cells to establish their own tissue architecture, producing a stratified epidermis supported by a biologically relevant dermal compartment. The result is a highly characterised skin equivalent that exhibits key hallmarks of fresh human skin while providing the reproducibility required for routine laboratory research.
Built on the Alvetex® Advanced platform, REPROSKIN is designed to make live human skin research more practical. Researchers can access the epidermal surface for topical dosing, UV exposure, tape stripping and barrier function measurements, while the flexible insert format supports downstream analysis and longitudinal studies.
REPROSKIN is suitable for a wide range of applications, including dermatology research, toxicology, cosmetic testing, wound healing studies, pigmentation research and mechanistic investigations of skin biology. Models are available for use within your own laboratory or through REPROCELL's contract research services, providing flexibility to match your research needs.
Why Choose REPROSKIN
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Human-relevant biology
Primary human fibroblasts and keratinocytes form a full-thickness tissue architecture. -
Customer control
Teams can run studies in their own laboratories rather than relying only on outsourced service work. -
Practical testing window
Fresh shipment and acclimatisation support experiments for up to seven days. -
Application breadth
Accessible epidermal surface enables topical dosing, probes, barrier measurements and wound-healing workflows.
Key Benefits of REPROSKIN
- Full-thickness human skin equivalent with epidermal and dermal layers.
- Constructed from primary human skin cells.
- Developed using our proprietary Alvetex® Advanced 3D tissue bioengineering technology.
- Accessible epidermal surface for topical applications and exposure studies.
- Supports barrier function, safety, efficacy and mechanistic research.
Note: REPROCELL's Preclinical Drug Discovery CRO also has a REPROSKIN bioengineered 3D tissue model assay service.