Products for iPSC Research
REPROCELL offers a variety of ready-to-ship products to support induced pluripotent stem cell (iPSC) research, including established iPSC lines, the StemRNA 3rd Gen Reprogramming Kit to generate your own lines. Also media, cell substrates, and reagents you need to do your own reprogramming and culture iPSCs.
Products for MSC Research
REPROCELL offers a variety of ready-to-ship products to support research with Mesenchymal Stem Cells (MSCs)—also called “Mesenchymal Stromal Cells” or "Medicinal Signaling Cells". These products include primary MSCs, iPSC-derived cell lines, media, and other culture reagents. Our cell lines are useful for differentiation and exosome production, enabling the development of diverse disease models for advanced research.
%20vial.jpg)
StemRNA™ Research iPSCs
Off-the-Shelf Lines
StemRNA human iPSCs (a.k.a. hiPSCs) provide immediate access to the state-of-the-art Stemgent StemRNA 3rd Gen Reprogramming technology. These cells are ideal for validating the StemRNA 3rd Gen Technology with control cells prior to investing in reprogramming to develop patient-derived cell lines.
Our StemRNA human iPSCs are derived from more than ten healthy and neurodegenerative disease donors with a range of demographic and clinical backgrounds. This means they do not contain vectors, viruses, or DNA – unlike iPSCs created using other reprogramming methods.
StemRNA human iPSCs are research-ready and free for commercial applications, including vaccine testing and drug screening.
StemEdit™ Gene Edited iPSCs
Off-the-Shelf Lines
REPROCELL has developed high-quality HLA knockout iPSC lines using StemEdit—our state-of-the-art genome editing technology, utilizing a proprietary nuclease system. It is also well-suited for clinical gene-editing projects.
In humans, the B2M protein is required for the presentation of HLA proteins A-G on the cell surface. Disruption of the B2M gene reduces T-cell activation and interferes with the T-cell-mediated immune response through inhibition of Class I HLA signaling. CIITA regulates the expression of the HLA Class II complex. Knocking out CIITA leads to reduced activity of HLA Class II and suppression of the immune response.
Qkine® Growth Factors and Cytokines
Ethical and sustainable, Qkine's animal origin-free recombinant growth factor and cytokine proteins are overexpressed in E.coli and tested to guarantee high levels of purity, excellent lot-to-lot consistency, and correct folding for high levels of bioactivity. All proteins are supplied lyophilized and shipped at ambient temperature, with a reconstitution solution also provided at no cost.
Qkine's large range of cost-effective and reliable proteins are manufactured at scale with full traceability. Applications include stem cell research and maintenance, physiologically relevant organoid models, organ-on-a-chip technologies, and cellular agriculture. Qkine products are used by research institutions, pharma, and biotech companies around the world.
Products for 3D Cell Culture
Three-dimensional (3D) cell culture has grown in interest for tissue engineering and drug discovery applications by providing a more physiologically relevant cellular structure. 3D culture allows cells to interact in all directions with their surrounding cellular and extracellular neighbours.
REPROCELL offers a variety of 3D cell culture technologies to support a range of experimental designs, from skin models to cancer invasion to in vivo implantation to embryoid body formation:
- Alvetex® by REPROCELL
- AteloCell® Atelocollagen by KOKEN
- EZSPHERE™ microwell dishes and plates by AGC
Alvetex® 3D Cell Culture Systems
3D cell cultures using REPROCELL’s Alvetex® technology deliver more in vivo-like results over traditional two-dimensional monolayer cultures. Alvetex allows cell biologists to maintain the integrity of cell structure and organization found within native tissue to better understand cellular biology.
Alvetex® Advanced Tissue Bioengineering System
Alvetex® Advanced is REPROCELL’s next-generation 3D tissue platform, designed for scientists who need biologically relevant, reproducible models such as skin for testing pharmaceuticals, cosmetics, chemicals, and devices. Powered by our proven Alvetex® scaffold technology, it creates the most accurate engineered human tissue available on the market.
Advanced Culture Plates
REPROCELL's advanced bespoke deep (extra capacity) plates can be used for standard cell culture applications giving users further options to modify media volumes and design co-culture studies.
The Alvetex Perfusion Plate allows scientists to create cell based models that are similar to the environment experienced by cells and tissue in vivo.
ABLE® Bioreactor Systems
Growth of induced pluripotent stem cells (iPSCs) in suspension culture in a bioreactor forms spheroids that closely resemble embryoid body structures naturally formed by embryonic stem cells.
ABLE Biott's cost-effective disposable bioreactor system utilizes this growth format to offer improved yield, viability and high efficiency for the expansion and differentiation of human iPSCs.
Custom Oligonucleotide Synthesis
Now offering its services worldwide, Bioserve India (part of the REPROCELL Group) is the pioneer for oligonucleotide synthesis in India. Since 2002 Bioserve has been delivering the highest quality products. At our world-class facility, we synthesize large quantities of oligonucleotides using high-throughput automated machines.
We offer a complete line of custom oligonucleotide synthesis and purification services based on customer requirements. Our expertise in nucleic acid chemistry enables us to provide our clients with an extensive selection of oligo dyes, quenchers, modified bases, linkers, spacers, and other related conjugates.
.jpg?width=1000&height=562&name=blog%20images%20(1).jpg)
