The ureter is a structure that connects the kidneys to the bladder. It has a smooth muscle layer that propels urine to the bladder via peristalsis. Our organ bath system can be used to assess the effect of your test article on ureter relaxation (or contraction).
Image: An example of human ureter sections isolated in our Glasgow laboratory.
Assess whether your test article causes relaxation of the ureters, with phenylephrine as a reference compound.