The REPROCELL Blog | Stem Cells: research, reports and resources

Epigenetic Modifications: Their Role in iPSC Reprogramming and Differentiation

02 May 2025

Explore the critical role of epigenetic mechanisms like DNA methylation and histone modifications in iPSC reprogramming and differentiation. Learn how optimizing epigenetic stability enhances reprogramming efficiency, reduces variability, and ensures safer, more reliable iPSC applications for research and therapy.

REPROCELL Connects with Maryland Governor Moore During His Japan Visit

22 April 2025

Maryland Governor Moore strengthens biotech ties with Japan, highlighting REPROCELL's pivotal role in the Maryland-Kanagawa partnership during his trade mission.

Exosomes from Stem Cells: iPSC vs. MSC-Derived Exosomes for Aesthetic and Regenerative Medicine

14 April 2025

Discover how iPSC and MSC-derived exosomes revolutionize skin rejuvenation and anti-aging treatments in aesthetic medicine. Main Point Summary: The blog explores the potential of exosomes derived from induced pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs) for skin rejuvenation and anti-aging treatments in aesthetic medicine, comparing their effectiveness, mechanisms, and applications.

Can Stem Cells Revolutionize Sustainable Food Production?

31 March 2025

Discover how stem cell technology is transforming sustainable food production, offering ethical and scalable alternatives to conventional meat, dairy, and seafood.

Qkineʼs Animal-Free Growth Factors and Cytokines are ideal for Stem Cell Culture

07 March 2025

Qkine's growth factors and cytokines are of exceptional bioactivity and purity - essential for maintaining and differentiating stem cell cultures.

Prince George’s County Economic Development Corporation Visits REPROCELL USA

03 March 2025

REPROCELL USA hosts Prince George's County Economic Development Corporation, showcasing their biotech services and highlighting the benefits of operating in PG County.

The Therapeutic Advantage of Induced Pluripotent Stem Cells-Derived Mesenchymal Stem Cells (iMSCs)

24 February 2025

Discover the clinical benefits and advancements of using induced pluripotent stem cells-derived mesenchymal stem cells (iMSCs) in regenerative medicine and therapeutic applications.

Breaking Barriers in Women’s Health: The World’s First Live Birth Using Fertilo

21 January 2025

Discover how Gameto achieved the world’s first live birth using Fertilo, a revolutionary in vitro oocyte maturation technology. Learn about its stem cell-driven innovation and how it's transforming fertility care for women worldwide.

From Fibroblasts to Cancer-Attacking Cells: Insights from Recent Research on Natural Killer Cells Derived from Clinical Grade iPSCs

16 October 2024

Discover the differentiation potential of induced pluripotent stem cells (iPSC) to cytotoxic NK cells, including recent advancements in research and therapy.

What you should know about the FDA’s Biological License Application Process

19 September 2024

Learn about the FDA's Biological License Application process, including submission requirements, review phases, and expedited pathways for biologics approvals.

REPROCELL USA Inaugurates New GMP Laboratory

07 June 2024

May 15, 2024: REPROCELL USA inaugurated its new GMP BioManufacturing Lab. The facility enables hiPSC and hMSC generation in a contaminant-free environment.

Harnessing the Power of Mesenchymal Stem Cells

27 May 2024

Discover the groundbreaking potential of Mesenchymal Stem Cells (MSCs) in biomedical research and therapeutic development.

Quality Control: What is really in your hiPSC culture?

11 December 2023

Whatever the goals of your project, a robust QC testing protocol assessing sterility, pluripotency, and genetic abnormalities, while maintaining sample identity, is critical.

Exploring CHIR99021: The Key to Stem Cell Research and Beyond

20 November 2023

CHIR 99021 effects on Wnt/β-catenin pathway

Editing B2M and CIITA to Create Hypoimmune Cell Lines for Cell Therapy

29 August 2023

Gene editing is a viable approach for reducing immunogenicity of iPSC-derived therapeutic cells. The B2M and CIITA HLA-regulatory genes are good targets.

Recombinant Human Laminins and their Use in Cell Culture

05 January 2023

Discover the biological processes that laminin regulates. Learn more about the use of laminin in stem cell research and culture.

REPROCELL’s Stemgent Brings mRNA Reprogramming to the Clinical Sector

14 October 2022

Discover how REPROCELL has employed its StemRNA™ 4th Generation Reprogramming Technology to bring the power of mRNA reprogramming to the clinical sector.

How SynFire® Technology can benefit your research

03 March 2022

SynFire neural cells more closely resemble real human biology than many other iPSC-based systems, resulting in better prediction of compound behaviour.

Everything you need to know about the REPROCELL iPSC Biobank

30 November 2021

Interested in learning about our off-the-shelf iPSCs? Read our blog article and discover everything you need to know about the REPROCELL iPSC Biobank.

How we established an in vitro Parkinson’s Disease model

24 November 2021

Discover how to establish an in vitro Parkinson’s Disease model using iPSC-derived neurons - from patient screening to neuronal maturation.

How digital droplet PCR can improve CRISPR gene editing (with examples)

05 October 2021

Looking to understand how digital PCR can improve your genome editing projects? Learn how digital PCR can improve your CRISPR gene editing (with examples).

What is digital droplet PCR and how can it improve stem cell therapies?

13 September 2021

Discover the definition of digital droplet PCR and how can it improve the safety of your stem cell therapies.

The ultimate guide to REPROCELL’s GMP iPSC manufacturing service

09 September 2021

Find out everything you need to know about REPROCELL's clinical stem cell services in our ultimate guide to REPROCELL’s GMP iPSC manufacturing service.

The ultimate guide to REPROCELL’s stem cell research services

16 August 2021

Looking to outsource your stem cell research project? Discover everything you need to know in our ultimate guide to REPROCELL’s stem cell research services

Will mRNA change medicine for good?

12 August 2021

Find out if mRNA will change medicine for good. Read about the molecules rise to fame in 2020 and how it could be used to treat diseases such as cancer.

Our top 10 stem cell culture products

02 July 2021

Read our countdown of the op 10 stem cell culture products sold by REPROCELL as chosen by our customers.

Protocol for immunocytochemistry of stem cells

29 January 2021

Read our tried-and-tested protocol for immunocytochemistry of stem cells and optimize your antibody concentrations.

Five reasons to choose StemRNA 3rd Gen Reprogramming Technology

04 December 2020

Looking for a more efficient iPSC reprogramming kit? Discover five reasons you should choose StemRNA 3rd Gen Reprogramming Technology for iPSC generation.

CRISPR-Cas9: Big Data, Precision Medicine and Universal Cell Therapy

13 April 2020

Find out how CRISPR-Cas9 can enhance big data, precision medicine, and universal cell therapy on the REPROCELL blog.

How CRISPR-SNIPER compares to other gene editing techniques

01 April 2020

Want to find out how CRISPR-SNIPER compares to other gene editing techniques? Discover the benefits of this advanced editing system on the REPROCELL blog.

A Visual Guide to CRISPR-SNIPER Gene Editing [INFOGRAPHIC]

30 March 2020

Discover the benefits of our advanced genome editing system in this visual guide to CRISPR-SNIPER gene editing [INFOGRAPHIC].

How is Stemchymal® performing in Clinical Trials? [INFOGRAPHIC]

16 March 2020

Wondering how is Stemchymal® performing in Clinical Trials? Discover the main findings from Stemchymal's clinical trials in our infographic.

3 challenges facing the introduction of iPSC-derived therapies

12 February 2020

Discover three of the main challenges facing the introduction of iPSC-derived therapies on the REPROCELL blog.

Cost Effective, Lab-scale Spheroid Culture of iPSCs

21 January 2020

Looking for cost effective, lab-scale, spheroid culture of iPSCs? Discover how the ABLE Bioreactor enables smarter cell production - no experience needed.

Stem cells offer hope for sufferers of Spinocerebellar Ataxia

08 November 2019

Discover how stem cell treatments can offer hope for sufferers of Spinocerebellar Ataxia (SCA).

How to mass culture induced pluripotent stem cells (iPSCs)

30 October 2019

Discover how to mass culture induced pluripotent stem cells (iPSCs) using a reactor culture system on the REPROCELL blog.

Improve Gene-Editing Success with CRISPR-SNIPER Technology

29 October 2019

The Ultimate Guide to CRISPR-SNIPER technology: a gene-editing system that overcomes the limitations of conventional CRISPR systems.

Which stem cell reprogramming technology should I use?

17 October 2019

Wondering which stem cell reprogramming technology you should use for your iPSC project? Discover the pros and cons of RNA Reprogramming from REPROCELL.

What is CRISPR-SNIPER Gene Editing?

02 September 2019

Discover the definition of CRISPR-SNIPER and how this advanced gene editing system can improve your edits.

Pluripotent Potential for Clinical Application

25 July 2019

Discover the potential of induced pluripotent stem cells (iPSCs) for clinical application on the REPROCELL blog.

Stem Cells for Autism

03 April 2019

Visit the REPROCELL blog and find out how stem cells could be used to treat autism in the future.

Neurite Outgrowth Assays using StemRNA Neuro

20 March 2019

Find out more about REPROCELL's neurite outgrowth assay that uses StemRNA Neuro cells.

Using human iPSCs as an in vitro model for regenerative medicine and disease modelling

22 February 2019

The conventional drug discovery pathway is a very inefficient process with the majority of candidate drugs not reaching the market due to safety and/or efficacy issues. But the use of iPSCs allows high throughput screening of therapies and disease-specific treatment using patient-specific models.

Tissue Sourcing for the Development of iPSC-derived Disease Models

06 February 2019

Looking to source primary tissues for iPSC generation? Find out more about tissue sourcing for the development of iPSC-derived disease models.

Xeno-free culture of stem cells in NutriStem® hPSC XF medium

05 February 2018

Find out more information about the xeno-free culture of stem cells using NutriStem® hPSC XF medium.

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