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Bio-Engineered 3D Tissue Models Using Alvetex™

For more than 15 years REPROCELL’s CSO, Professor Stefan Przyborski, has harnessed our award-winning Alvetex 3D scaffold technology to test pharmaceutical compounds in skin, liver, and neuronal tissues. By combining the human relevance of our iPSC-derived cell lines with Alvetex technology, our team can develop a solution for your 3D in vitro assay needs.

Because human cells exist in three dimensions (3D) in vivo, culturing them in a two-dimensional (2D) format results in loss of form and function. Bio-engineered 3D tissue models have repeatedly demonstrated a more accurate response to drugs, chemicals, and cosmetics than their 2D counterparts because:

  • They more closely mimic human tissue micro-anatomy
  • They are more phenotypically accurate e.g. maintenance of CYP450 activity in 3D in comparison with 2D culture
  • They allow you to interrogate the mechanisms of action of your compound with confidence

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