Chorionic plate arteries 

The chorionic plate arteries supply nutrients to the growing fetus and are essential for healthy development. Pre-eclampsia is characterized by reduced maternal-fetal blood flow, which can pose increased health risks for both the mother and fetus. We can assess the effects of your test article on the vasodilation of normal or pre-eclamptic arteries. 

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Bradykinin model

The model assesses whether your test article causes vasodilatation in human chorionic plate arteries via bradykinin receptors.

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Sildenafil model

The model assesses whether your test article causes vasodilatation in human chorionic plate arteries via PDE5.

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Pre-eclamptic Bradykinin model

The model assesses whether your test article causes vasodilatation in pre-eclamptic chorionic plate arteries via bradykinin receptors.

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Pre-eclamptic Sildenafil model

The model assesses whether your test article causes vasodilatation in pre-eclamptic chorionic plate arteries via PDE5.