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Alvetex® Plasticware Formats

A broad range of formats for growing cells in 3D culture.

 

3D cell cultures using REPROCELL’s Alvetex technology deliver more in vivo-like results over traditional two-dimensional monolayer cultures. Alvetex allows cell biologists to maintain the integrity of cell structure and organization found within native tissue to better understand cellular biology.

All Alvetex products are made from the same inert polystyrene material as standard 2D cell culture plasticware. Cell biologists can quickly experience the many benefits of 3D cell culture and at the same time easily transition between 2D and 3D experiments. Alvetex is available in a wide range of plate and well insert formats supporting a broad range of cell and tissue type environments for cells to penetrate, grow and proliferate in 3D.

Each product unit has been terminally sterilised by gamma irradiation and remains sterile until its blister pack is opened. Alvetex requires an ethanol wash prior to use to render it hydrophilic, and it does not degrade during normal use.

Alvetex Scaffold Multiwell Plate Formats

Alvetex Scaffold 12 well plate

alvetex-12-well-plate

Comprised of a single loose disc of Alvetex Scaffold and a polystyrene clip in each well of a 12 well plate. The clip holds the disc in position during transit and use, and can easily be removed for access to the Alvetex Scaffold and cells grown in 3D culture.

The 12 well plate format, a simple presentation of Alvetex Scaffold technology, is primarily suitable for short term culture experiments where the medium is replaced every 1-2 days.

Units are individually sterile blister packed.

alvetex-12-well-plate-drawing

Alvetex® Scaffold 12 well plate (with lid)

  • AVP002-2 — 2 × 12 well plates
  • AVP002-10 — 10 × 12 well plates
  • AVP002-80 — 80 × 12 well plates

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Alvetex Scaffold 24 well plate

alvetex-scaffold-24-well-plate

Comprised of a single loose disc of Alvetex Scaffold and a polystyrene clip in each well of a 24 well plate. The clip holds the disc in position during transit and use, and can easily be removed for access to the Alvetex Scaffold and cells grown in 3D culture.

The 24 well plate format, a simple presentation of Alvetex Scaffold technology, is primarily suitable for short term culture experiments where the medium is replaced every 1-2 days.

Units are individually sterile blister packed.

alvetex-24-well-plate-drawing

Alvetex® Scaffold 24 well plate (with lid)

  • AVP006-2 — 2 × 24 well plates
  • AVP006-10 — 10 × 24 well plates
  • AVP006-80 — 80 × 24 well plates

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Alvetex Scaffold 96 well plate

alvetex-96-well-plate

Comprised of a black 96 well plate, clear plastic base, with Alvetex Scaffold at the bottom of each well. The Alvetex Scaffold has been heat welded to the base of the wells in a process which does not alter its physical structure.

Cells growing in 3D are exposed to culture medium from above only, and therefore predominantly reside in the top portion of scaffold.

Alvetex Scaffold 96 well plate technology is compatible with a wide range of in vitro cell viability assays.

Units are individually sterile blister packed.

alvetex-96-well-plate-drawing

Alvetex® Scaffold 96 well plate (with lid)

  • AVP009-2 — 2 × 96 well plates
  • AVP009-10 — 10 × 96 well plates
  • AVP009-80 — 80 × 96 well plates

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Alvetex Scaffold 384 well plate

alvetex-384-well-plate

Comprised of a black 384 well plate, clear plastic base, with Alvetex Scaffold at the bottom of each well. The Alvetex Scaffold has been heat welded to the base of the wells in a process which does not alter its physical structure.

Cells growing in 3D are exposed to culture medium from above only, and therefore predominantly reside in the top portion of scaffold.

Alvetex Scaffold 96 well plate technology is compatible with a wide range of in vitro cell viability assays.

Units are individually sterile blister packed.

alvetex-384-well-plate-drawing-2

Alvetex® Scaffold 384 well plate (with lid)

Alvetex Scaffold / Alvetex Strata Well Insert Formats

Alvetex 6 Well Insert Format

alvetex-6-well-insert

Comprised of discs of either Alvetex Scaffold or Alvetex Strata in individually sealed polystyrene inserts, designed to fit into most 6 well plates (see diagram).

6 well inserts can also be suspended in a deep Petri dish using our custom-made Alvetex Well Insert Holder (see product AVP015, sold separately).

The presentation of Alvetex in well insert formats is versatile, enabling long term 3D culture as cells can receive nutrients from media above and below the membrane, sustaining optimal 3D cell growth.

Inserts are individually sterile blister packed.

alvetex-6-well-insert-drawing

Alvetex® Scaffold 6 well inserts

  • AVP004-12 — 12 inserts
  • AVP004-48 — 48 inserts
  • AVP004-96 — 96 inserts

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Alvetex® Strata 6 well inserts

  • STP004-12 — 12 inserts
  • STP004-48 — 48 inserts
  • STP004-96 — 96 inserts

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Alvetex 12 Well Insert Format

alvetex-12-well-insert

Comprised of discs of either Alvetex Scaffold or Alvetex Strata in individually sealed polystyrene inserts, designed to fit into most 6 well and 12 well plates (see diagram).

12 well inserts (when their extender wings haven’t been snapped off) can also be suspended in a deep Petri dish using our custom-made Alvetex Well Insert Holder (see product AVP015, sold separately).

The presentation of Alvetex in well insert formats is versatile, enabling long term 3D culture as cells can receive nutrients from media above and below the membrane, sustaining optimal 3D cell growth.

Inserts are individually sterile blister packed.

alvetex-12-well-insert-drawing

Alvetex® Scaffold 12 well inserts

  • AVP005-12 — 12 inserts
  • AVP005-48 — 48 inserts
  • AVP005-96 — 96 inserts

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Alvetex® Strata 12 well inserts

  • STP005-12 — 12 inserts
  • STP005-48 — 48 inserts
  • STP005-96 — 96 inserts

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Alvetex 24 Well Insert Format

alvetex-scaffold-24-well-insert

Comprised of discs of either Alvetex Scaffold or Alvetex Strata in individually sealed polystyrene inserts, designed to fit into most 12 well and 24 well plates (see diagram).

The presentation of Alvetex in well insert formats is versatile, enabling long term 3D culture as cells can receive nutrients from media above and below the membrane, sustaining optimal 3D cell growth.

24 well inserts are sterile blister packed in units of 12 within a 12 well plate.

alvetex-24-well-insert-drawing

Alvetex® Scaffold 24 well inserts

  • AVP012-12 — 12 inserts
  • AVP012-48 — 48 inserts
  • AVP012-96 — 96 inserts

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Alvetex Tools

Alvetex Well Insert Holder and Deep Petri Dish

alvetex-well-insert-holder

Comprised of a single well insert holder in a deep Petri dish with lid. The well insert holder is capable of housing up to three Alvetex well inserts (either 6 or 12 well inserts). The Petri dish itself is not tissue culture treated.

The Alvetex Well Insert Holder and Deep Petri Dish enables users to grow their 3D cultures in larger volumes of media compared to an ordinary multiwell plate, facilitating fewer media changes. Capable of sustaining long term 3D culture experiments (3-4 weeks).

The well insert can be positioned at three different levels in the insert holder: high, medium and low. This feature allows cultures to be raised to the air liquid interface by moving the insert to a different level within the same holder.

Positioning the well inserts at different levels may also be used to conserve expensive media or allow for increasing media volumes for demanding cell types over the course of a long term experiment.

Units are individually sterile blister packed.

 

Well inserts at different holder levels:

alvetex-well-insert-holder-levels-drawing


Alvetex Perfusion Plate

alvetex-perfusion-plate

This product allows scientists to create cell based models that are another step closer to the environment experienced by cells and tissue in vivo. The systems can also be used to create complex co-cultures, multi-organ systems and to study paracrine effects.

Each unit contains an Alvetex Perfusion Plate with a lid and two Luer locks.

Note: Pump and tubing is not included.

Plate units are individually sterile blister packed.

 

Alvetex Kits

Product Kit Contents

Alvetex® Scaffold Plate Starter Kit
AVP-KIT-1

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  • 1 × 12 well plate
  • 1 × 24 well plate
  • 1 × 96 well plate

Alvetex® Scaffold Well Insert Starter Kit
AVP-KIT-2

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  • 6 × 6 well inserts
  • 6 × 12 well inserts
  • 1 × Alvetex Well Insert Holder in a deep Petri dish

Alvetex® Strata Well Insert Starter Kit
STP-KIT-2

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  • 6 × 6 well inserts
  • 6 × 12 well inserts
  • 1 × Alvetex Well Insert Holder in a deep Petri dish

Alvetex® Perfusion Plate and Alvetex Scaffold 6 Well Inserts Kit (small)
AVP-KIT-3

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  • 2 × Alvetex Perfusion Plates with Luer locks
  • 12 × Alvetex Scaffold 6 well inserts

Alvetex® Perfusion Plate and Alvetex Scaffold 12 Well Inserts Kit (small)
AVP-KIT-4

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  • 2 × Alvetex Perfusion Plates with Luer locks
  • 12 × Alvetex Scaffold 12 well inserts

Alvetex® Perfusion Plate and Alvetex Scaffold 6 Well Inserts Kit (large)
AVP-KIT-5

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  • 5 × Alvetex Perfusion Plates with Luer locks
  • 48 × Alvetex Scaffold 6 well inserts

Alvetex® Perfusion Plate and Alvetex Scaffold 12 Well Inserts Kit (large)
AVP-KIT-6

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  • 5 × Alvetex Perfusion Plates with Luer locks
  • 48 × Alvetex Scaffold 12 well inserts

All units are individually sterile blister packed.

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