BioThrust ComfyCell Incu 300mL Starter Package (Spheroids/Aggregates)

Starter Package containing [1×] BioThrust ComfyCell Incu Base Unit (100-240 VAC) (available separately as BT-INT-NC-CTR-INCU), and [3×] BioThrust ComfyCell Incu Single-Use Bioreactor 300mL (for Spheroids/Aggregates) (each available separately as BT-INT-C-ISU-0.3-2).

ComfyCell Incu Single-Use Bioreactor 300mL (for Spheroids/Aggregates)

A revolutionary single-use disposable 300mL bioreactor for scaled and intensified sensitive cell cultivation to be used with the BioThrust ComfyCell Incu system. This version of the ComfyCell Incu Single-Use Vessel 300mL is optimized for ultra-sensitive single cells or aggregate processes, such as organoids or self-aggregating PSC spheroids. Adaptation of the Membrane Stirrers’ supporting structure and slight reduction of the hollow fiber packing density within each of the 16 blades of the Membrane Stirrer enable even the most sensitive processes to be run.

Note: ComfyCell bioreactors BT-INT-C-ISU-0.3-2 are optimized for culture of ultra-sensitive cells or self-aggregating spheroids. For more robust single cells (e.g. T-Cells, NKs, HEK, CHO) and microcarriers, see ComfyCell bioreactor BT-INT-C-ISU-0.3-1.

ComfyCell Incu Base Unit (100-240 VAC)

The ComfyCell Incu Base unit contains a motor, a pump for aeration and LEDs for illumination. These provide consistent stirring & active aeration (leveraging an incubator atmosphere) of ComfyCell Incu 300mL disposable bioreactors.

The motor mechanically connects to the BioThrust ComfyCell Incu Single-Use Bioreactor 300mL from the top to drive the Membrane Stirrer inside the vessel. The pump is connected via silicone tubing to actively aerate the media with high efficiency by pushing the incubators atmosphere through the hollow fiber membrane blades.

 BioThrust company name and logo are the property of BioThrust GmbH, Germany. 

Product Name: BioThrust ComfyCell Incu 300mL Starter Package (Spheroids/Aggregates)

Catalog Number: BT-INT-PACK-INCU-0.3-2

Size: 1 pack

Pack components:

• 1 × BioThrust ComfyCell Incu Base Unit (100-240 VAC) (available separately as BT-INT-NC-CTR-INCU)
• 3 × BioThrust ComfyCell Incu Single-Use Bioreactor 300mL (for Spheroids/Aggregates) (each available separately as BT-INT-C-ISU-0.3-2)

Sterility: Bioreactor vessels are not sterile (autoclave at user site)

Vessel Properties:

• Individually packaged
• To be autoclaved for sterility
• Contact materials are tested for biocompatibility & leachability

Accessories included (on each vessel): 3× PG13.5 port plugs, 2× silicone tubing & filters for gas connections, 4× c-flex tubing, Luer locks & clamps for sampling/ harvesting ports. (All components delivered pre-installed on vessel, no manual assembly required).

Intended Use: This product is for research use only, not for therapeutic or diagnostic purposes. Not for resale or for commercial purposes without permission from REPROCELL.

Notice To Purchaser: REPROCELL is a licensed distributor of BioThrust ComfyCell Incu bioreactor products worldwide

Manufacturer: BioThrust GmbH (Germany)

Product Sheet:

• BioThrust ComfyCell Technical Sheet

Operating Instructions:

• BioThrust ComfyCell Incu 300 mL Technical Manual

Posters:

• Advancing human iPSC cultivation processes in bionic bioreactors
  Patrick Bongartz, Yasemin van Heuvel, Misha Teale, Daniel Terheyden-Keighley

Publications:

• Upscaling: efficient generation of human lung organoids from induced pluripotent stem cells using a stirring bioreactor
  Bettina Budeus, Chiara Kroepel, Zehra Fatma Sevindik ,Luca Fabian Buttler and Diana Klein. 01 December 2025, Frontiers in Bioengineering and Biotechnology. DOI 10.3389/fbioe.2025.1684315

Application Notes:

• Evaluation of BioThrust's MemStir: iPSC-Derived Cardiomyocyte Expansion in 2 L
• Evaluation of BioThrust's MemStir: Human Lung Organoid Expansion in 2L
• BioThrust's 2L ComfyCell: Technical Data & Simulations

• Simple and Scalable hiPSC Expansion in Suspension as Spheroids Using the BioThrust ComfyCell Incu Bioreactor Expansion in Suspension as Spheroids using the BioThrust ComfyCell Incu Bioreactor