CI-huThyrEC Immortalized Human Thyroid Epithelial Cells

CI-huThyrEC are immortalized human thyroid epithelial cells, which are also known as follicular cells or thyrocytes. Thyroid epithelial cells are the cells within the thyroid gland responsible for the production and secretion of thyroid hormones, primarily thyroxine (T4) and triiodothyronine (T3).

In vitro, thyroid follicular cells are used as a test system for endocrine disruptor screening, to study hormone synthesis or thyroid biology, for example, the thyroid autoimmune disorders Hashimoto’s disease or Graves‘ disease.

Characteristics

• Secretion of TG
• TSH-responsive
• Expression of TPO in 3D cell culture
• Secretion of (low) amounts of T3 and T4 in 3D cell culture

Culture Conditions

• Culture Medium: huThyrEC Medium (Cat. No. INS-ME-1017)
• Culture Matrix: Epithelial Cell Coating Solution  (Cat. No. INS-SU-1020)
• Cryopreservation Medium: Freezing Solution for Immortalized Cell Lines (Cat. No. INS-SU-1004)

CI-ThyrEC stained with Phalloidin and DAPI.

Buying and Ordering the Cells

For non-profit organizations, cells are available for perpetual academic research under the Limited Research Use License. Please contact us about licenses for commercial organizations.

inscreenex company name and inscreenex brand name are the property of inscreenex GmbH, Germany.

Product Name

CI-huThyrEC

Product Description

Immortalized Human Thyroid Epithelial Cells

Strain

CI-huThyrEC

Catalog Number

INS-CI-1017

Donor Information

• Race: Caucasian
• Sex: Male
• Age: 18 years old

Precryopreservation Culture Conditions

• Culture Medium: huThyrEC Medium (Cat. No. INS-ME-1017)
• Culture Matrix: Epithelial Cell Coating Solution  (Cat. No. INS-SU-1020)
• Cryopreservation Medium: Freezing Solution for Immortalized Cell Lines (Cat. No. INS-SU-1004)
• BSL 1

Size

1 vial, 0.5 × 10⁶ cells per vial

Storage

Store in liquid nitrogen vapor phase.

Quality Control

• ICC for TG, TSHR, NKX2, KRT7: Pass
• Viability: >75%
• Bacteria: Negative
• Fungi: Negative
• Mycoplasma: Negative
• Virus (HIV1&2, HBV, HCV): Negative

Sterility

Sterile

Notice To Purchaser

This product is intended for Research Use Only.  Commercial Use may require additional agreements. Please contact us for more information.