PGS - Preclinical Genomic Services (Overview)

Overview

We offer a full suite of accurate and cost-effective preclinical molecular services both as a complement to our Global BioRepository and as a stand-alone business.

We specialize in smaller to mid-size projects, providing intense customer service from assay design to data delivery and discussion (with you) about your experiment results.

Here’s a snapshot of our current services:

Genotyping	DNA and RNA Extraction	Gene Expression
Assay Design Services Data Analysis Sequenom iPlex / MassARRAY Mass spec-based technology	Whole Blood, Blood Clots, Mouthwash, Buffy Coats, FFPE, Serum, Buccal Swabs, Tissues, Saliva, and more Non-organic reagents Column-based capabilities Custom-developed protocols Multiple Quality control practices Gel check, OD 260/280, TaqMan, pico green quantitation Tissues, Whole Blood, PAXgene tubes	Real-time PCR Life Technologies Viia7 Mutation Analysis Measure genomic DNA alterations Insertions, deletions, copy number variations TaqMan qPCR Predesigned assays Quantitative gene expression Nucleic acid quantitation

Genotyping

DNA and RNA Extraction

Gene Expression

Assay Design Services
Data Analysis
Sequenom iPlex / MassARRAY
Mass spec-based technology

Whole Blood, Blood Clots, Mouthwash, Buffy Coats, FFPE, Serum, Buccal Swabs, Tissues, Saliva, and more
Non-organic reagents
Column-based capabilities
Custom-developed protocols
Multiple Quality control practices
- Gel check, OD 260/280, TaqMan, pico green quantitation
Tissues, Whole Blood, PAXgene tubes

Real-time PCR

Life Technologies Viia7

Mutation Analysis
- Measure genomic DNA alterations
- Insertions, deletions, copy number variations
TaqMan qPCR
- Predesigned assays
- Quantitative gene expression
- Nucleic acid quantitation

Our in-house expertise in assay design, oligonucleotide synthesis and SNP validation enable us to deliver accurate data, quickly and cost-effectively. We specialize in smaller to mid-size projects, providing intense customer service from assay design to data delivery and discussing your experiment results.

We have over 25 years of experience with genomic DNA and RNA isolation from nearly all biomaterials. Samples are quantitated by optical density. Quality of DNA is determined through electrophoresis. RNA quality control checks are performed through Agilent’s Bioanalyzer.

Real-time PCR measures amplification cycle-by-cycle enables quantitative measurements during the exponential phase of PCR. We now utilize latest in the family of real-time PCR instruments by Applied BioSystems — the ViiA7™.

CLIA certified molecular diagnostic tests utilizing FDA approved GenMark Dx platform.