Easy iMatrix-511 SILK Stem Cell Culture Substrate

NP892-024

Brand: iMatrix

Easy iMatrix-511 SILK is a ready-to-use solution of iMatrix-511 silk. Easy iMatrix-511 silk is useful for the culture of cells adhering to laminin-511.

Currency: 

Product name Product code Pack size Price (USD) Price (GBP) Price (EUR)
Easy iMatrix-511 SILK Stem Cell Culture Substrate (100 mL) NP892-024 100 mL $ 305.00 £ 270.00 € 316.00

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Note: prices shown do not include shipping and handling charges.

iMatrix-511 is a highly purified and refined laminin-511 E8 fragments, produced in CHO cells.

iMatrix-511 features make it an ideal matrix for pluripotent stem cell culture:

  • Promotes greater stem cell adhesion than all other matrix proteins that have been tested
  • Easy to use (liquid format)
  • E8 fragments retain integrin binding specificity and capacity and display higher potency than natural Laminin-511
  • Equivalent performance, but lower cost than the legacy iMatrix-511 product

Laminin is localized to the basement membrane and plays a key role in cell adhesion and proliferation. Laminin-511 (α5, β1 laminin) binds to integrin α6β1 to promote cell signaling. Laminin-511 provides an ideal matrix for the proliferation of a wide variety of cell types including stem and iPS cells.

iMatrix-511 is functionally equivalent to iMatrix-511 SILK (Cat. No. NP892-021). The only difference is the expression system used for bioproduction. The iMatrix-511 SILK product is produced in recombinant silkworm cocoon, while iMatrix-511  is produced in CHO-S cells. Both are E8 fragments that have been purified using the same processes.

Matrixome company name and logo and iMatrix brand name are the property of Matrixome Corp., Japan.

Specifications

Product Name: iMatrix-511 Stem Cell Culture Substrate

Catalog Numbers:

  • NP892-011
  • NP892-012

Sizes:

  • NP891-011: 2 × 175 µg
  • NP891-012: 6 × 175 µg

Molecular Weight: 150 kDa

Purity: > 95 % pure

Formulation: Purified Laminin-511 E8 proteolytic fragment

Storage and Stability: Store at 4 °C and protect from light exposure. Stable for 2 years from manufacturing date.

Concentration: 500 µg/mL

Source: CHO cells

Quality Control: Integrin binding Kd < 10 nM

Sterility: Sterile

Notice To Purchaser: REPROCELL is a licensed distributor of Matrixome cell culture substrates to the global market.

Recommended Usage: iMatrix-511 is suitable for use as a substrate for culture of various cell types, including ES/iPS cells.

Manufacturer: Matrixome Corporation (Japan)