iMatrix Recombinant Human Laminin E8 fragments provide a controlled, reproducible source of matrix for culture of iPSCs and other cell types. The Laminin fragments are expressed in either CHO cells or silk-worms, and the laminin subtype is optimized for various cell types.
NP892-071 / NP892-072
iMatrix-111 is a highly purified and refined product of human recombinant laminin-111 (E8 fragment) expressed by CHO-S cells. Laminin 111 supports the survival, proliferation, and differentiation of many different cell types in vitro. However, its distribution after birth is restricted to only a few tissues, such as the brain and kidney.
NP892-061 / NP892-062
iMatrix-221 is a xeno-free, recombinant Laminin-221 E8 Fragment expressed in CHO-S cells. Laminins of the α2-isoform are commonly found in the basal lamina of striated muscle and the predominant form found in adult human heart tissue.
NP892-031 / NP892-032
iMatrix-332 is a highly purified and refined product of human recombinant laminin-332 (E8 fragment) expressed by CHO-S cells. Laminin 332 supports cells in the epithelial basement membranes, lining the surfaces of the body such as the skin, hair follicles, oral cavity, gastrointestinal and urinary tracts, lungs, and different glands.
NP892-041 / NP892-042
iMatrix-411 is a xeno-free, recombinant Laminin-411 E8 Fragment expressed in CHO-S cells. Laminin-411 is found predominantly in the vascular endothelial basement membrane. Stem cells cultivated on iMatrix-411 are robustly induced to differentiate into endothelial progenitor cells.
An alternative iMatrix-511 that is xeno-free, recombinant Laminin-511 E8 Fragment expressed in silkworm for promoting adherence and culture of human iPS cells.
NP892-011 / NP892-012
iMatrix-511 is a xeno-free, recombinant Laminin-511 E8 Fragment produced in CHO-S cells and used with the StemRNA-3rd Gen Reprogramming Kit (00-0076) to generate iPS cells from fibroblasts, blood or urine.