Easy iMatrix-511 SILK Stem Cell Culture Substrate

Easy iMatrix-511 SILK is a ready-to-use solution of iMatrix-511 SILK.

iMatrix-511 SILK is functionally equivalent to iMatrix-511 SILK (Cat. No. NP892-011). The only difference is the expression system used for bioproduction. The iMatrix-511 SILK product is produced in recombinant silkworm cocoon, while iMatrix-511  is produced in CHO-S cells. Both are E8 fragments that have been purified using the same processes.

iMatrix-511 features make it an ideal matrix for pluripotent stem cell culture:

• Promotes greater stem cell adhesion than all other matrix proteins that have been tested
• Easy to use (liquid format)
• E8 fragments retain integrin binding specificity and capacity and display higher potency than natural Laminin-511
• Equivalent performance, but lower cost than the legacy iMatrix-511 product

Laminin is localized to the basement membrane and plays a key role in cell adhesion and proliferation. Laminin-511 (α5, β1 laminin) binds to integrin α6β1 to promote cell signaling. Laminin-511 provides an ideal matrix for the proliferation of a wide variety of cell types including stem and iPS cells.

Matrixome company name and logo and iMatrix brand name are the property of Matrixome Corp., Japan.

Specifications

Product Name: Easy iMatrix-511 SILK Stem Cell Culture Substrate

Catalog Numbers:

• NP892-024

Sizes:

• NP891-024: 100 mL

Molecular Weight: 150 kDa

Purity: > 95 % pure

Formulation: Recombinant iMatrix-511 SILLK E8 fragments in PBS(-) with 0.05% recombinant human serum albumin

Storage and Stability: Store at 2 °C to 15 °C, protected from light exposure. Stable for 2 years from manufacturing date.

Concentration: 1.6 µg/mL

Source: silkwork cocoons

Quality Control: Integrin binding K_d ≤ 10 nM

Sterility: Sterile

Notice To Purchaser: REPROCELL is a licensed distributor of Matrixome cell culture substrates to the global market.

Recommended Usage: iMatrix-511 is suitable for use as a substrate for culture of various cell types, including ES/iPS cells.

Manufacturer: Matrixome Corporation (Japan)