Brand: iMatrix™ by Matrixome®
Purchase product: USA Store
|Product Code||Pack Size||Price in
|Prices in UK, Europe,
Middle East & Africa
|NP892-041||175 μg × 2 tubes||USD $ 621.00||GBP £ 557.41||EUR € 632.67|
|NP892-042||175 μg × 6 tubes||USD $ 1,553.00||GBP £ 1,393.52||EUR € 1,581.69|
Prices do not include shipping and handling charges.
iMatrix-411 is a xeno-free, recombinant Laminin-411 E8 Fragment expressed in CHO-S cells. Laminin-411 is found predominantly in the vascular endothelial basement membrane. Stem cells cultivated on iMatrix-411 are robustly induced to differentiate into endothelial progenitor cells.
iMatrix-411 features make it an ideal matrix for some cell culture applications:
iMatrix-411 is a highly purified and refined product of human recombinant laminin-411 (E8 fragment) expressed by CHO-S cells. Laminin-411 is found predominantly expressed in the vascular endothelial basement membrane1 and in Langerhans islet capillary endothelial cells of the pancreas.2
As a cell culture ECM-substrate iMatrix-411 can assist in establishing human endothelial cell primary cultures from fresh human bio-specimens.
Human iPS cells, when cultured on iMatrix-411, are robustly induced (>95%) to differentiate into endothelial progenitor cells with angiogenesis capacity.1 Other published reports have used iMatrix-411 and iMatrix-511 in a step-wise protocol to generate cholangiocytes capable of forming 3D cyst-structures from iPSC-derived hepatoblastic cells.3
Product Name: iMatrix-411 Endothelial Cell Substrate
Molecular Weight: 150 kDa
Purity: > 95 % pure
Formulation: Purified Laminin-411 E8 proteolytic fragment
Storage and Stability: Store at 4 °C and protect from light exposure. Stable for 2 years from manufacturing date.
Quality Control: Activity: Kd for integrin binding
Notice To Purchaser: REPROCELL is a licensed distributor of Matrixome cell culture substrates to the global market
Recommended Usage: iMatrix-411 is suitable for use as a substrate for culture of various cell types, but most notably for vascular endothelial cells.
Concentration: 500 µg/mL
Source: CHO-S cell expression
Manufacturer: Matrixome Corporation (Japan)
Stem Cells / 13 September 2021
Clinical Capabilities / 9 September 2021
15 September 2021
2 September 2021
18 August 2021
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