StemRNA™ Sensory Neurons

iPSC-derived Sensory Neurons

Frozen human iPSC-derived neurons for high throughput and high content assays

Please Enquire for Price orders-us@reprocell.com

Sensory neurons transmit pain signals generated by trauma, temperature, or chemicals to the central nervous system. Primary afferent nerves, evoked by non-nociceptive and nociceptive stimuli, reside in the dorsal root ganglion (DRG) of the spinal cord. REPROCELL has developed an alternative sensory neuron model using human-derived induced pluripotent stem cells (iPSC) to negate accessibility issues and improve ease of culture. These cells' expression of sensory markers was detected by immunocytochemistry. Multi-Electrode Array (MEA) analysis confirms these hiPSC-derived sensory nerves display the same functionality as primary DRG cells.

Requires Sensory Neuron Culture Medium (Cat. No. RDCN103).

 

StemRNA Sensory Neurons Respond to the irritant capsaicin.

 

StemRNA Sensory Neurons show activation with increasing temperature, while iPSC-derived cortical neurons do not.

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Stemgent and the StemRNA brand name are trademarks of REPROCELL Inc., Japan.

Product Name

StemRNA Sensory Neurons

Catalog Number

RCDN004N

Size

1 vial

Storage and Stability

Store in liquid nitrogen

Brochure

• REPROCELL Stemgent StemRNA™ Sensory Neurons – iPSC-derived Neurons for Disease Modeling and Drug Screening
  

Additional Publications

• Hiranuma M; Okuda Y; Jujii Y; Richard J-P; Watanae T. Characterization of human iPSC-derived sensory neurons and their functional assessment using multi electrode array. Sci Rep 14:6011 (2024).