Atelocollagen Honeycomb Sponge (discs)
Lyophilized Atelocollagen sponge shows a honeycomb structure with high pore density and unidirectional characteristics. This honeycomb structure enables easy delivery of nutrients to cells, and transport of excreted waste products away from cells.
|Product name||Product code||Pack size||Price (USD)||Price (GBP)||Price (EUR)|
|Atelocollagen Honeycomb Sponge (discs)||KKN-CSH-96||25 pieces||$ 410.00||£ 404.51||€ 472.47|
Note: prices shown do not include shipping and handling charges.
The 'Honeycomb' collagen sponge has a structure in which uniform pores (250-400 um) are arranged densely in one direction, into which cells can penetrate and proliferate. This structure facilitates the ready supply of nutrients to the cells inside the sponge, and releases metabolic wastes and biochemical products. Cells can proliferate and fill the lumen to form a uniform cell mass. The 'Honeycomb' collagen sponge is prepared from highly purified bovine dermal type I Atelocollagen and can be degraded by collagenase.
Suppression of tumorigenesis from transplanted mouse ES cells by cultivation with Atelocollagen Honeycomb Sponge. (M. Yamaki, Matsumoto Dental University, Japan)
Mouse ES cells cultured on honeycomb sponge were transplanted by subcutaneous injection into 6-week-old mice. Although all embryoid bodies without the honeycomb sponge formed tumor without exception, none of the embryoid bodies transplanted with the honeycomb sponge formed tumors (Fig.1).
Histological analysis of transplanted (mouse ES/+CSH) and normal kidney showed no differences between the two tissues. The results indicates normal spontaneous differentiation of the mouse ES cells in the presence of the honeycomb sponge when transplantedin vivo(Fig.2).
KOKEN company name and logo and AteloCell brand are the property of KOKEN Corp. Ltd., Japan.
Product Name: Atelocollagen Honeycomb Sponge
Catalog Number: KKN-CSH-96
Size: 100 mg (bottle)
- 6 mm diameter × 2 mm sponges
- 12-13 mg/mL density
- 200-400 µm pore size
- approx. 2000 cm²/ g surface area
Storage and Stability: Store at Room Temperature
Notice To Purchaser: REPROCELL is a licensed global distributor of KOKEN’s collagen-derived products everywhere, except for Japan.
Manufacturer: Koken Co., Ltd. (Japan)