REPROCELL Resources Online

Alvetex Publications: 101 and up (newest)

A list of Publications in Scientific Journals detailing research where Alvetex™ has been used.

The publications below are hosted on the websites of various scientific journals.



Extracellular Vesicles From a Three-Dimensional Culture of Perivascular Cells Accelerate Skin Wound Healing in a Rat
Min Ho Kim, Changho Chung, Mun Ho Oh, Jin Hyun Jun, Yong Ko & Jong Hun Lee

Aesthetic Plastic Surgery, 05 April 2021


SIRT1 Inhibits Apoptosis by Promoting Autophagic Flux in Human Nucleus Pulposus Cells in the Key Stage of Degeneration via ERK Signal Pathway
Fei He, Qingshu Li, Bo Sheng, Haitao Yang, and Wei Jiang

BioMed Research International, vol. 2021, Article ID 8818713.


Use of Porous Polystyrene Scaffolds to Bioengineer Human Epithelial Tissues In Vitro
Costello L, Darling N, Freer M, Bradbury S, Mobbs C, Przyborski S

Methods in Molecular Biology (Clifton, N.J.), 1 January 2021
DOI: 10.1007/978-1-0716-1246-0_20

In vitro epithelial models are valuable tools for both academic and industrial laboratories to investigate tissue physiology and disease. Epithelial tissues comprise the surface epithelium, basement membrane, and underlying supporting stromal cells. There are various types of epithelial tissue and they have a diverse and intricate architecture in vivo, which cannot be successfully recapitulated using two-dimensional (2D) cell culture. Tissue engineering strategies can be applied to bioengineer the organized, multilayered, and multicellular structure of epithelial tissues in vitro. Alvetex® is a porous, polystyrene scaffold that enables fibroblasts to synthesize a complex network of endogenous, humanized extracellular matrix proteins. This creates a physiologically relevant three-dimensional (3D) subepithelial microenvironment, enriched with mechanical and chemical cues, which supports the organization and differentiation of epithelial cells. Such technology has been used to bioengineer different epithelial architectures in vitro, including the simple, columnar structure of the intestine and the stratified, squamous, and keratinized structure of skin. Epithelial tissue models provide a useful platform for fundamental and translational research, with multifaceted applications including disease modeling, drug discovery, and product development.


Generation of Keratinocytes from Human Induced Pluripotent Stem Cells Under Defined Culture Conditions
Shyam Kishor Sah, Jitendra K. Kanaujiya, I-Ping Chen, and Ernst J. Reichenberger

Cellular Reprogramming, 29 December 2020
DOI: 10.1089/cell.2020.0046


The human bone marrow harbors a CD45CD11B+ cell progenitor permitting rapid microglia‐like cell derivative approaches
Andreas Bruzelius Isabel Hidalgo Antonio Boza‐Serrano Anna‐Giorgia Hjelmér Amelie Tison Tomas Deierborg Johan Bengzon Tania Ramos‐Moreno

Stem Cells Translational Medicine, 09 December 2020
DOI: 10.1002/sctm.20-0127


Exposure of the SH-SY5Y Human Neuroblastoma Cells to 50-Hz Magnetic Field: Comparison Between Two-Dimensional (2D) and Three-Dimensional (3D) In Vitro Cultures
Claudia Consales, Alessio Butera, Caterina Merla, Emanuela Pasquali, Vanni Lopresto, Rosanna Pinto, Maria Pierdomenico, Mariateresa Mancuso, Carmela Marino & Barbara Benassi

Molecular Neurobiology, 24 November 2020


Developing a novel 3D model of the intestinal epithelium as a tool to study the pharmacokinetics of new chemical entities
Matthew A. Freer

Doctoral Thesis, Durham University, UK
25 September 2020


Bioengineering Novel in vitro Co-culture Models That Represent the Human Intestinal Mucosa With Improved Caco-2 Structure and Barrier Function
Nicole J. Darling, Claire L. Mobbs, Ariana L. González-Hau1, Matthew Freer and Stefan Przyborski

Frontiers in Bioengineering and Biotechnology
31 August 2020


E7 oncoprotein from human papillomavirus 16 alters claudins expression and the sealing of epithelial tight junctions
Perla Yaceli Uc, Jael Miranda, Arturo Raya‑Sandino, Lourdes Alarcón, María Luisa, Roldán Rodolfo, Ocadiz‑Delgado, Enoc Mariano Cortés‑Malagón, Bibiana Chávez‑Munguía, Georgina Ramírez, René Asomoza, Liora Shoshani, Patricio Gariglio, Lorenza González‑Mariscal

International Journal of Oncology
29 July 2020
DOI: 10.3892/ijo.2020.5105


Spheroid Trapping and Calcium Spike Estimation Techniques toward Automation of 3D Culture
Kenneth Ndyabawe, Mark Haidekker, Amish Asthana, William S. Kisaalita

SLAS Technology
16 July 2020
DOI: 10.1177/2472630320938319