ReproHP Medium

Catalog RCRM201
Size 500 mL
Price Price on Request
$150.00
Availability In stock
Catalog
RCRM201

Product Overview

A breakthrough in the culture of Primary Human Hepatocytes 

ReproHP Medium enables the robust culture of primary human hepatocytes, enhancing and prolonging the detection of most CYP450 detoxification enzymes.  Boosted basal expression levels, enhanced induction levels and lasting enzyme activity in primary human hepatocytes are key effects of ReproHP medium. 

Higher Cytochrome P450 expression levels

When cultured in ReproHP Medium and exposed to specific drugs, the basal and induced expression levels of key detoxification enzymes (CYP3A4, CYP1A2, CYP2B6) are significantly elevated in primary human hepatocytes.

*Experimental Notes: Reported expression values are normalized against the basal expression level of another “leading brand”. The data shown is from one lot of primary human hepatocytes (Life Technologies) taken at Day 4 in culture. Other human primary hepatocyte lots showed similar patterns of enhanced expression with ReproHP Medium™.

3D Culture Leads to Higher Performance

Culturing primary human hepatocytes on the Alvetex scaffold in ReproHP Medium™ further boosts CYP3A4 basal expression levels and induced levels after drug induction.


Product Specifications

Product Name
ReproHP Medium
Catalog Number
RCRM201
Size
500 mL
Formulation
Contains several small molecules that assist in stabilizing the health and longevity of primary human hepatocytes in culture
Storage and Stability
Storage temperature:-20℃
Endotoxin Level
contain 0.19% CHIR99021 (in supplement)

Product Specifications

Product Name
ReproHP Medium
Catalog Number
RCRM201
Size
500 mL
Formulation
Contains several small molecules that assist in stabilizing the health and longevity of primary human hepatocytes in culture
Storage and Stability
Storage temperature:-20℃
Endotoxin Level
contain 0.19% CHIR99021 (in supplement)