Part of the Alvetex product line, the Perfusion Plate is a 4-well plate system engineered for perfusion cell culture, where cell culture medium is continuously circulated in either an open or closed loop. This ensures that nutrients are continually refreshed and metabolic waste or secreated products are continuosly flushed. The 4 wells are connected sequentially such that medium flows into the first well and is flushed into the downstream wells during the perfusion process. Designed to be used with any peristaltic pump system, the plate is provided ready-to-use, sterile and disposable. The plate can be used for adherent cell culture (plate surfaces are biocompatible and uncoated) or with Alvetex hanging well inserts for 3D cell culture formats. The plate design will accomodate the 6 or 12-well Alvetex hanging well design.