There are many possible devices to promote 3D spheroid formation for use with homogeneous cell populations or mixed-populations. The formation of spheroids of iPS cells (sometimes called embryoid bodies or EB) is a frequently employed cell culture technique to enhance efficiencies of differentiation or to create functional organoids that mimic tissue function. The EZSPHERE cell culture dishes from Asahi Glass Company (AGC) is a unique non-adherent dish product line with microwells that collect cells in microwells and promote spheroid formation through natural processes. Each plate is laser-etched giving high precision with microwells of consistent size, and even allowing for custom sizes to be manufactured on-demand. Several different plate sizes are available, including microwell plate formats. The variety of microwell sizes that exist allow you to customize your spheriods for yields and cluster sizes. And if you are uncertain, a sample pack is available with one plate from many different microwell configurations.