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Predictive Drug Discovery Assays

REPROCELL’s predictive drug discovery assays include:

Cardiac Assays

Our selection of human cardiac models offer a unique insight into the effects your test compounds will elicit in the clinical setting.

Vascular Assays

Normally used to confirm the absence of off-target effects or prevent dilemmas caused by species variation, human vascular tissues are frequently available. Vascular tissue can be secured from both healthy donors and donors with a range of diseases including diabetes, hypertension and atherosclerosis.

Respiratory Assays

REPROCELL is able to offer an extensive range of assays in fresh human lung tissue from healthy and diseased non-transplantable lungs or surgical residual tissues.

Gastrointestinal Assays

REPROCELL is able to access almost all regions of the GI tract including stomach and the small and large intestine. Tissue is available from both healthy and diseased individuals and tissues are available from patients suffering from inflammatory bowel disease (IBD).

ADME/DMPK Assays

REPROCELL is able to provide information on the absorption and metabolism characteristics of your compounds in ex vivo human respiratory, skin and gastrointestinal tissues by employing Ussing Chambers to mount intact sheets of human epithelium that retain all the relevant characteristics to model passive and active transport of substances.

Skin/Skin Model Assays

REPROCELL is able to provide information on the absorption and metabolism characteristics of your compounds in ex vivo human respiratory, skin and gastrointestinal tissues by employing Ussing Chambers to mount intact sheets of human epithelium that retain all the relevant characteristics to model passive and active transport of substances.

Genitourinary Assays

REPROCELL is able to offer an extensive range of assays in human genitourinary tissues including bladder, uterus and prostate.

Comparative Pharmacology Assays

REPROCELL can directly compare drug responses across species, helping you to translate your data from preclinical animal species to humans.

Other Assay Requests

Can't find the service you're looking for?

From diseased human tissue sourcing and genotyping through iPSC establishment, cell differentiation, characterization, culture of 3D organoids and pre-clinical human tissue assays to partnering your Regenerative Medicine clinical trials, we can custom tailor services to your specific needs. We can even do custom R&D for you. Leave it to the experts.

Make an Inquiry to discuss your specific needs

 

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