Preclinical Genomic Services

Accelerating breakthroughs in genetics, drug discovery, biomarker research, and molecular diagnostics.

Overview

We offer a full suite of accurate and cost-effective preclinical molecular services both as a complement to our Global BioRepository and as a stand-alone business.

We specialize in smaller to mid-size projects, providing intense customer service from assay design to data delivery and discussion (with you) about your experiment results.

Here’s a snapshot of our current services:

 

GenotypingDNA and RNA ExtractionGene Expression
  • Assay Design Services
  • Data Analysis
  • Sequenom iPlex / MassARRAY
  • Mass spec-based technology
  • Whole Blood, Blood Clots, Mouthwash, Buffy Coats, FFPE, Serum, Buccal Swabs, Tissues, Saliva, and more
  • Non-organic reagents
  • Column-based capabilities
  • Custom-developed protocols
  • Multiple Quality control practices
    • Gel check, OD 260/280, TaqMan, pico green quantitation
  • Tissues, Whole Blood, PAXgene tubes
  • Real-time PCR
    • Life Technologies Viia7
  • Mutation Analysis
    • Measure genomic DNA alterations
    • Insertions, deletions, copy number variations
  • TaqMan qPCR
    • Predesigned assays
    • Quantitative gene expression
    • Nucleic acid quantitation

 

Genotyping

Our in-house expertise in assay design, oligonucleotide synthesis and SNP validation enable us to deliver accurate data, quickly and cost-effectively. We specialize in smaller to mid-size projects, providing intense customer service from assay design to data delivery and discussing your experiment results.

DNA And RNA Extraction

We have over 25 years of experience with genomic DNA and RNA isolation from nearly all biomaterials. Samples are quantitated by optical density. Quality of DNA is determined through electrophoresis. RNA quality control checks are performed through Agilent’s Bioanalyzer.

Gene Expression and Allelic Discrimination (RT PCR)

Real-time PCR measures amplification cycle-by-cycle enables quantitative measurements during the exponential phase of PCR. We now utilize latest in the family of real-time PCR instruments by Applied BioSystems — the ViiA7™.

Molecular Diagnostic Testing (CLIA Certified)

CLIA certified molecular diagnostic tests utilizing FDA approved GenMark Dx platform.

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