Human Brain AlzheimerÕs Disease Model Neurons derived by Transfection.
ReproNeuro iPSC-derived neurons are delivered as a suspension of frozen single cells that retain structural and functional integrity, and high viability thanks to REPROCELLÕs proprietary cryopreservation technology. Thawed and plated, ReproNeuro cells mature during 2-3 weeks of culture on surfaces treated with ReproNeuro Coat (RCDN201).
Schematic showing preparation of neural progenitor cells from human iPS cells which were transfected mutated (P117L) presenilin 1gene
StemRNA Neuro AD-Mutation Neurons
3 × 106 cells
Storage and Stability
Store in liquid nitrogen
Makoto Honda, Itsunari Minami, Norie Tooi, Nobuhiro Morone, Hisae Nishioka, Kengo Uemura, Ayae Kinoshita, John E. Heuser, Norio Nakatsuji, Kazuhiro Aiba. The modeling of Alzheimer's disease by the overexpression of mutant Presenilin 1 in human embryonic stem cells. Biochemical and Biophysical Research Communications 469, 3(2016):587-592