Genomic Sequencing Services (DNA and RNA)

REPROCELL provides a broad portfolio of Next Generation Sequencing (NGS) services, drawing on 25 years of experience in sequencing technologies, and supported by a bioinformatics team dedicated to helping you interpret your results.

 

WGS Services

 

Whole Genome Sequencing (WGS) provides the most comprehensive map of an organism's genetic make-up, which covers all corners of an organisms’ entire genome. Exome sequencing focuses on targeted sequencing of the protein coding regions of the genomic DNA, which can facilitate identification of unknown inheritable conditions. Targeted resequencing is an effective method for analyzing the desired genes/SNPs/regions of interest for population studies or disease related variant discovery by next generation sequencing; whether you are interested in a few genes, or a few hundred genes. 

 

Transcriptomics Services

 

We offer a small RNA sequencing service that enables analysis of novel miRNA & other small RNA species. This application covers novel smRNA discovery, mutation characterization & expression profiling of smRNAs. RNA-Seq (also called whole transcriptome sequencing; WTS) reveals the presence and quantity of RNA in a biological sample at a given moment. Temporal WTS reveals the continuously changing cellular transcriptome.

 

Epigenomics Servces

 

Whole genome bisulfite sequencing is an effective and reliable strategy to identify individually methylated cytosines on a genome and simultaneously observe the methylation patterns of all CpG, CHG and CHH sites present in the sample of interest. Chip-Seq is a method to analyze protein interactions with DNA. Chip-Seq combines with chromatin immunoprecipitation with massively parallel DNA sequencing to identify binding sites of DNA-associated proteins

 

Microbial Genomics Services

 

16s rRNA gene is a highly conserved component, and it is the most widely used gene marker for genus, species, taxonomic identification significance in bacteria and archaea.

 

Other Related Services

 

For more that 40 years, Sanger sequencing has been used to get high quality long read (up to 500 bp or more) sequencing reads. While largely replaced by next-gen sequencing methods for genomic scale sequencing, Sanger sequencing is widely used for small scale projects such as sequencing PCR products and plasmid inserts.

REPROCELL provides small and large scale oligonucleotide synthesis for a variety of purposes with more than 20 available base modifications.

Overarching all of these technologies is REPROCELL’s highly experienced bioinformatics team, who are ready to help you get the information you need out of the mountains of data obtained in a large-scale sequencing project. We can help you determine where the known genes are, identify sequence variations, and predict what the clinical ramifications of any mutations observed.

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