Transdifferentiation reagents

Product Classification : DifferentiationResearch Theme : Differentiation

Transdifferentiation reagents

Stemgent Brand

Modified mRNAs for the transdifferentiation of human and mouse fibroblasts into skeletal muscle and cardiomyocytes.


Product list

RNA transfection reagents

Catalog No. Product Quantity Price
00-0069Stemfect RNA Transfection Kit1 KitAsk
05-0020eGFP mRNA20 μgAsk

Modified mRNAs for transdifferentiation

Catalog No. Product Quantity Price
05-0033Gata4 mRNA, HumanCardiomyocytes20 μgAsk
05-0034Mef2c mRNA, Human20 μgAsk
05-0035Tbx5 mRNA, Human20 μgAsk
05-0031Myf5 mRNA, HumanMyogenic lineage20 μgAsk
05-0029MyoD mRNA, HumanSkeletal Muscle20 μgAsk
05-0032Myog mRNA, HumanSkeletal Muscle20 μgAsk

Presentations

  • Dixon JE, et al. (2011) Directed differentiation of human embryonic stem cells to interrogate the cardiac gene regulatory network. Mol Ther. 19(9):1695-703.
  • Angel M, Yanik MF. (2010) Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins. PLoS One. 5(7):e11756.
  • Warren L, et al. (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell. 7(5):618-30.
  • Ieda M, et al. (2010) Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell. 142(3):375-86.
  • Ghosh TK, et al. (2009) Physical interaction between TBX5 and MEF2C is required for early heart development. Mol Cell Biol. 29(8):2205-18.
  • Charron F, et al. (1999) Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression. Mol Cell Biol. 19(6):4355-65