Publications — BioServe

2010Bhatia K, Modali R, Goedert JJ. Merkel cell polyomavirus is not detected in mesotheliomas. J Clin Virol. 2010 Feb;47(2):196-8. Epub 2009 Dec 16.
2009Murphy G, Cross AJ, Sansbury LS, Bergen A, Laiyemo AO, Albert PS, Wang Z, Yu B, Lehman T, Kalidindi A, Modali R, Schatzkin A, Lanza E. Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention Trial. Int J Cancer. 2009 May 1;124(9):2148-51.
2009Bhatia K, Goedert JJ, Modali R, Preiss L, Ayers LW. Merkel cell carcinoma subgroups by Merkel cell polyomavirus DNA relative abundance and oncogene expression. Int J Cancer. 2009 Jun 23;126(9):2240-2246.
2009Bhatia K, Goedert JJ, Modali R, Preiss L, Ayers LW. Immunological detection of viral large T antigen identifies a subset of Merkel cell carcinoma tumors with higher viral abundance and better clinical outcome. Int J Cancer. 2009 Dec 29.
2008Murphy G, Sansbury LS, Bergen AW, Wang Z, Schatzkin A, Lehman T, Kalidindi A, Modali R, Lanza E. Polynucleotide kinase 3′ phosphatase variant, dietary variables and risk of adenoma recurrence in the Polyp Prevention Trial. Eur J Cancer Prev. 2008 Jun;17(3):287-90.
2008Quick Sylvia K; Shields Peter G; Nie Jing; Platek Mary E; McCann Susan E; Hutson Alan D; Trevisan Maurizio; Vito Dominica; Modali Ramakrishna; Lehman Teresa A; Seddon Mike; Edge Stephen B; Marian Catalin; Muti Paola; Freudenheim Jo L. Effect modification by catalase genotype suggests a role for oxidative stress in the association of hormone replacement therapy with postmenopausal breast cancer risk. Cancer epidemiology, biomarkers and prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(5):1082-7.
2008Murphy G, Sansbury LB, Cross AJ, Stolzenberg-Solomon R, Laiyemo A, Albert PS, Wang Z, Schatzkin A, Lehman T, Kalidindi A, Modali R, Lanza E. Folate and MTHFR: risk of adenoma recurrence in the Polyp Prevention Trial. Cancer Causes Control. 2008 Sep;19(7):751-8. Epub 2008 Mar 6.
2006Sansbury, L.B., Bergen, A.W., Wanke, K.L., Yu, B., Caporaso, N.E., Chatterjee, N., Ratnasinghe, L., Schatzkin, A., Lehman, T.A., Kalidindi, A., Modali, R., Lanza, E. Inflammatory cytokine gene polymorphisms, nonsteroidal anti-inflammatory drug use, and risk of adenoma polyp recurrence in the polyp prevention trial. Cancer Epidemiol Biomarkers Prev. 2006 Mar;15(3):494-501.
2006Gaudet, M.M., Bensen, J.T., Schroeder, J., Olshan, A.F., Terry, M.B., Eng, S.M., Teitelbaum, S.L., Britton, J.A., Lehman, T.A., Neugut, A.I., Ambrosone, C.B., Santella, R.M., Gammon, M.D. Catechol-O-methyltransferase haplotypes and breast cancer among women on Long Island, New York. Breast Cancer Res Treat. 2006 Apr 5; [Epub ahead of print].
2005Lin, T.S., Flinn, I.W., Modali, R., Lehman, T.A., Webb, J., Waymer, S., Moran, M.E., Lucas, M.S., Sherif, F.S., Byrd, J.C. FcRI{gamma}IIa and FcR{gamma}IIa Polymorphisms May Not Correlate with Response to Alemtuzumab (Campath-1H) in Chronic Lymphocytic Leukemia (CLL). Blood 105: 289-291, 2005.
2005Stone A, Ratnasinghe LD, Emerson GL, Modali R, Lehman T, Runnells G, Carroll A, Carter W, Barnhart S, Rasheed AA, Greene G, Johnson DE, Ambrosone CB, Kadlubar FF, Lang NP. CYP3A43 Pro(340)Ala polymorphism and prostate cancer risk in African Americans and Caucasians. Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1257-61.
2004Farag, S.S., Flinn, I.W., Modali, R., Lehman, T.A., Byrd, J.C. Fc(gamma)RIIIa and Fc(gamma)RIIa polymorphisms do not predict response to rituximab in B-cell chronic lymphatic leukemia. Blood 103: 1472-1474, 2004.
2003Kamel, F., Umbach, D.M., Lehman, T.A., Park, L.P., Munsat, T.L., Shefner, J.M., Sandler, D.P., Hu, H., Taylor J.A. Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes. Environ Health Perspect. 111: 1335-9, 2003.
2003Martinez, A., Lehman, T.A. Modali, R., Mulshine, J.L. The ras family of oncogenes in development and progression of lung cancer. Screening of mutations by polymerase chain reaction-based ligase chain reaction. Methods Mol Med. 74:187-200, 2003.
2003Woodson, K., Tangrea, J.A., Lehman, T.A., Modali, R., Taylor, K.M., Snyder, K., Taylor, P.R., Virtamo, J., Albanes, D. Manganese superoxide dismutase (MnSOD) polymorphism, alpha-tocopherol supplementation and prostate cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study (Finland). Cancer Causes Control. 14: 513-518, 2003.
2001Byrd, J.C., Shinn, C., Willis, C.R., Flinn, I.W., Lehman, T., Sausville, E., Lucas, D., Grever, M.R. UCN-01 induces cytotoxicity toward human CLL cells through a p53 independent mechanism. Exp Hematol 29 (6) 703-708, 2001.
2001London, S., Xia, J., Lehman, T., Yang, J.H., Granada, E., Chunhong, L., Dubeau, L, Li, T., David-Beabes, G., Li, Y. Collection of buccal cell DNA in seventh-grade children using water and a toothbrush. Cancer Epidemiology, Biomarkers and Prevention 10: 1227-1230, 2001.
2000Lehman, T.A., Haffty, B.G., Carbone, C.J., Bishop, L.R., Gumbs, A.A., Krishnan, S., Shields, P.G., Modali, R., Turner, B.C. Elevated frequency and functional activity of a specific germ-line p53 intron mutation in familial breast cancer. Cancer Res. 60:1062-1069, 2000.
1999Berger, D.H., Chang, H., Wood, M., Huang, L., Heath, C.W., Lehman, T., Ruggeri, B.A. Mutational activation of K-ras in nonneoplastic exocrine pancreatic lesions in relation to cigarette smoking status. Cancer 85: 326-329, 1999.
1999Panguluri R C; Brody L C; Modali R; Utley K; Adams-Campbell L; Day A A; Whitfield-Broome C; Dunston G M. BRCA1 mutations in African Americans. Human genetics 1999;105(1-2):28-31.
1998Byrd, J.C., Shinn, C., Waselenko, J.K., Fuchs, E.J., Lehman, T.A., Nguyen, P.L., Flinn, I.W., Diehl, L.F., Sausville, E., Grever, M.R. Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53. Blood 92:3804-16, 1998.
1997London, S.J., Lehman, T.A., and Taylor, J.A. Myeloperoxidase genetic polymorphism and lung cancer risk. Cancer Res. 57: 5001-5003, 1997.
1997Scott, F., Modali, R., Lehman, T.A., Seddon, M., Kelly, K., Dempsey, E.C., Wilson, V., Tockman, M.S., and Mulshine, J.L. High frequency of K-ras mutations in bronchial alveolar lavage fluid of patients at high risk for second primary lung cancer. Clin. Cancer Res. 3: 479-482, 1997.
1997Gopalakrishnan, R., Weghorst, C.M., Lehman, T.A., Bijur, G., Sabourin, C.L.K., Mallery, S.R., and Stoner, G.D. p53 expression and HPV in proliferative verrucous leukoplakia. Oral Surgery, Oral Med., Oral Path., Oral Rad., and Endodontics. 83: 471-477, 1997.
1997Caloca, M.J., Fernandez, N., Lewin, N.E., Ching, D., Modali, R., Blumburg, P.M., Kazanietz, M.G. Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters. J. Biol. Chem. 272: 26488-26496, 1997.
1996Ohnuki, Y., Reddel, R., Bates, S.E., Lehman, T.A., et al. Chromosomal changes and progressive tumorigenesis of human bronchial epithelial cell lines. Cancer Genet. Cytogenet. 92: 99-110, 1996.
1996Lehman, T.A., Scott, F., Seddon, M., Kelly, K., Dempsey, E.C., Wilson, V.L., Mulshine, J.L., and Modali, R. Detection of K-ras oncogene mutations by polymerase chain reaction-based ligase chain reaction. Anal. Biochem. 239: 153-159, 1996.
1995Harris, C., Pfeifer, A., Lehman, T., Weston, A., Gerwin, B. and Lechner, J.: Oncogenes and tumor suppressor genes in human carcinogenesis. Cancer Res. Clin. Oncol.
1995Speir, E., Huang, E.S., Modali, R., Leon, M.B., Interaction of human cytomegalovirus with p53: possible role in coronary restenosis. Scand. J. Infect. Dis. Suppl., 99: 78-81, 1995.
1994Speir, E., Modali, R., Leon, M., Shawl, F., Guzman, R., Finkel, T., Huang, E. S., Griner, J., Choi, B., and Epstein, S. E. Evidence suggesting a causal role of human cytomegalovirus in coronary restinosis: interaction with the tumor suppressor gene p53. Science 265: 391-394, 1994.
1994Lehman, T. A. and Harris, C. C.: Mutational spectra of protooncogenes and tumor suppressor genes: clues to predict cancer etiology. IARC Monograph. Vol. 125, Lyon, France, 1994, pp. 399-412.
1994Lehman, T. A., Greenblatt, M., Bennett, W. P. and Harris, C. C.: Mutational spectrum of the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Drug Metabol. Rev. 26: 221-235, 1994.
1994Hollstein, M., Marion, M.-J., Lehman, T., Welsh, J., Harris, C. C., Kusters, I., and Montesano, R.: p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers. Carcinogenesis. 15: 1-3, 1994.
1993Lehman, T.A., Modali, R., Stanek, J., Welsh, J., Bennett W. P., Stampfer, M., Boukamp, P., Fusenig, N., Rogan, E. M., Reddel, R. R. and Harris, C.C. p53 mutations in human immortalized epithelial cell lines. Carcinogenesis 14:833-839, 1993.
1993Esteve, A., Lehman, T., Jiang, W., Weinstein, I. B., Harris, C. C., Ruol, A., Peracchia, A., Montesano, R. and Hollstein, M.: Correlation of p53 mutations with epidermal growth factor receptor overexpression and absence of mdm2 amplification in human esophageal carcinomas. Mol. Carcinog. 8: 306-311, 1993.
1992Metcalf, R. A., Welsh, J. A., Bennett, W.P., Lehman, T. A., Pelin, K., Linnainmaa, K., Tammilehto, L., Mattson, K., Gerwin, B. I., and Harris, C. C.: p53 and Kirsten-ras mutations in human mesothelioma cell lines. Cancer Res. 52:2610-2615, 1992.
1992Cajot, J.-F., Anderson, M. J., Lehman, T. A., Shapiro, H., Briggs, A. A. and Stanbridge, E. J.: Growth suppression mediated by transfection of p53 in Hut292DM human lung cancer cells expressing endogenous wild-type p53 protein. Cancer Res. 52:6956-6960, 1992.
1992Lehman, T. A. and Harris, C. C.: Oncogene and tumor suppressor gene involvement in human lung carcinogenesis. Transformation of Human Epithelial Cells: Molecular and Oncogenetic Mechanisms, CRC Press, Florida, 1992, pp. 235-259.
1992Gerwin, B.I., Spillare, E., Forrester, K., Lehman, T.A., Kispert, J., Welsh, J.A., Pfeifer, A.M.A., Lechner, J.F., Baker, S.J., Vogelstein, B., and Harris, C.C.: Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor type 1. Proc. Natl. Acad. Sci. USA. 89: 2759-2763, 1992.
1991Harris, C. C., Bennett, W. P., Gerwin, B. I., Iman, D. S., Lehman, T. A., Metcalf, R. A., Pfeifer, A. M. A., Reddel, R. R., Sugimura, H. and Weston, A.: Oncogenes and tumor suppressor genes involved in human lung carcinogenesis. In Brugge, J., Curran, T., Harlow, E. and McCormick, F. (Eds.): Origins of Human Cancer, Cold Spring Harbor Laboratory Press, New York, 1991, pp. 739-744.
1991Lehman, T. A., Pfiefer, A. M. A., Metcalf, R. A., Bennett, W. P., Weston, A., Gerwin, B. I., and Harris, C. C.: Oncogenes and tumor suppressor genes in human lung carcinogenesis. In: Waxman, S. (Ed.) Second Volume on Differentiation Therapy. Raven Press, New York, 1991, pp. 87-98.
1991Lehman, T. A., Bennett, W. P., Metcalf, R. A., Reddel, R., Welsh, J. A., Ecker, J., Modali, R. V., Ullrich, S., Romano, J. W., Appella, E., Testa, J. R., Gerwin, B. I., Harris, C. C.: p53 mutations, ras mutations and p53-heat shock 70 protein complexes in human lung cell lines. Cancer Res. 51: 4090-4096, 1991.
1991Lehman, T. A., Reddel, R. R., Pfeifer, A. M. A., Spillare, E., Kaighn, M. E., Weston, A., Gerwin, B. I. and Harris, C. C.: Oncogenes and tumor suppressor genes. Environ. Health Perspect. 93: 133-144, 1991.
1991Lehman, T. A., and Harris, C. C. Neoplastic transformation and suppression of transformation of human bronchial epithelial cells in vitro. In Rhim, J.S. and Dritschilo A. (Eds.): Neoplastic Transformation in Human Cell Culture, The Humana Press, Inc., New Jersey. 1991, pp.251-258.
1990Harris, C. C., Reddel, R., Modali, R., Lehman, T. A., Iman, D., McMenamin, M., Sugimura, H., Weston, A. and Pfeifer, A.: Oncogenes and tumor suppressor genes involved in human lung carcinogenesis. In Sutherland, B. M. and Woodhead, A. D. (Eds.): DNA Damage and Repair in Human Tissues, New York, Plenum Press, 1990, pp. 363-380.
1990Harris, C. C., Reddel, R., Pfeifer, A., Amstad, P., Mark, G., Weston, A., Modali, R., Iman, D., McMenamin, M., Kaighn, E., Gabrielson, E., Jones, R. and Trump, B. F.: Oncogenes and tumor suppressor genes in human lung carcinogenesis. In Harris, C. C. and Liotta, L. (Eds.): Genetic Mechanisms in Carcinogenesis and Tumor Progression, New York, Wiley-Liss, 1990, pp 127-152.
1990Sugimura, H., Caporaso, N.E., Shaw, G.L., Modali, R.V., Gonzalez, F.J., Hoover, R.N., Resau, J.H., Trump, B.F., Weston, A. and Harris, C.C. : Human debrisoquine hydroxy¬lase gene polymorphisms in cancer patients and controls. Carcinogenesis 11: 1527-1530, 1990.
1990Sugimura, H., Caporaso, N. E., Hoover, R. N., Modali, R., Resau, J., Trump, B. F., Lonergan, J. A., Krontiris, T. G., Mann, D. L., Weston, A. and Harris, C. C.: Association of rare alleles of the Ha-ras-1 locus with lung cancer. Cancer Res. 50: 1857-1862, 1990.
1990Weston, A., Sugimura, H., Modali, R., Bowman, E.D., Caporaso, N.E., Manchester, D. K., Shields, P. G., Poirier, M. C. and Harris, C. C.: Molecular dosimetry, genetic susceptibility and cancer risk. In Volans, G. N., Sims, J., Sullivan, F.M. and Turner, P. (Eds.): Basic Science Proceedings of the V International Congress of Toxicology, Philadelphia, Taylor and Francis, Ltd., 1990, pp. 263-279.
1989Nigro, J. M., Baker, S. J., Preisinger, A. C., Jessup, J. M., Hostetter, R., Cleary, K., Bigner, S. H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Weston, A., Modali, R., Harris, C. C. and Vogelstein, B.: p53 gene mutations occur in diverse human tumor types. Nature, 342: 705-708, 1989.
1989Weston, A., Willey, J. C., Modali, R., Sugimura, H., McDowell, E., Resau, J., Light, B., Haugen, A., Mann, D. L., Trump, B. F. and Harris, C. C.: Differential DNA sequence deletions from chromosomes 3, 11, 13 and 17 in squamous cell carcinoma, large cell carcinoma and adenocarcinoma of the human lung. Proc. Natl. Acad. Sci. USA, 86: 5099-5103, 1989.
1989Kumari, H. L., Shuler, C. F., Lehman, T., Ferrone, S. and Milo, G. E.: Development of neoplastic phenotype following transfection of HNF cell with sarcoma DNA. Carcinogenesis, 10: 401-404, 1989.
1989Milo, G. E., Yohn, J., Schuller, D., Noyes, I. and Lehman, T.: Comparative stages of expression of human squamous carcinoma cells. J. Invest. Dermatol., 92: 848-853, 1989.
1989Lehman, T., Kurian, P. and Milo, G. E.: Metabolism of and DNA adduct formation by benzo[a]pyrene in human skin epithelial cells in vitro pretreated with cytochrome P450 modulators. Cancer Biochem. Biophys., 10: 345-352, 1989.
1988Yohn, J., Lehman, T. A., Kurian, P., Ribovich, M. and Milo, G.E.: Benzo[a]pyrene diol epoxide I modification of DNA in human skin xenografts. J. Invest. Dermatol., 91: 363-368, 1988.
1988Stoner, G. D., Shivapurkar, N. M., Schut, H. A. J. and Lehman, T.: DNA binding and adduct formation of 4,4-methylene-bis(2-chloroainline) (MOCA) in explant cultures of human and dog bladder. Cancer Lett., 39: 237-240, 1988.
1988Milo, G. E., Oldham, J. W., Noyes, I., Lehman, T. A., Kumari, H. L., West, R. W. and Kadlubar, F. F.: Cocarcinogenicity of saccharin and N-alkyl-nitrosoureas in cultured diploid human fibroblasts. J. Toxicol. Envirn. Health, 24: 413-421, 1988.
1988Yang, S. S., Modali, R., Park, J. B. and Taub, J. V.: Transforming DNA sequences of human hepatocellular carcinomas, their distribution and relationship with hepatitis B virus sequence in human hepatomas. Leukemia, 2: 102s-113s, 1988.
1987Shivapurkar, N., Lehman, T., Schut, H. A. J. and Stoner, G. D.: DNA binding of 4,4′-methylene-bis(2-chloroainline) (MOCA) in explant cultures of human and dog bladder. Cancer Lett., 38: 41-48, 1987.
1986Lehman, T., Noyes, I. and Milo, G. E.: Establishment and chemical and transformation of human skin epithelial cells in vitro. J. Tissue Culture Methods, 10: 197-203, 1986.
1986Modali, R. and Yang, S. S.: Specificity of aflatoxin B1 binding on human proto-oncogene nucleotide sequence. Prog. Clin. Biol. Res., 207: 147-158, 1986.
1985Yang, S. S., Taub, J. V., Modali, R., Vieira, W., Yasei, P. and Yang, G. C.: Dose dependency of aflatoxin B1 binding on human high molecular weight DNA in the activation of proto-oncogenes. Environ. Health Perspect., 62: 231-238, 1985.
1984NULLYang, S. S., Modali, R. and Yang, G. C.: Formation of aflatoxin B1-DNA adducts in normal rat and hepatoma tissue culture cells and in human livers from fetal, Reye’s syndrome and hepatocellular carcinoma. Advances in Gene Technology: Human Genetic Disorders, In: Ahmad, F., Black, S., Schultz, J., Scott, W. A. and Whelan, W. J. (Eds.), ICSU Press, Florida, pp. 272-273, 1984.
1984Yang, S. S., Modali, R. and Murphy, E., Jr.: Cloning of the rat endogenous helper leukemia virus DNA sequence and expression of the helper activity encoded by the cloned DNA sequence in normal rat kidney cells by micro-injection. Eucaryotic Cell Culture: Basic and Application. Advances in Experimental Medicine and Biology, 172, In: Acton, R. and Lynn, J. D. (Eds.), Plenum Press, New York, pp. 295-319, 1984.
1983Yang, S. S. and Modali, R.: An analysis of the genomic complexity of the cloned wild rat endogenous retrovirus (WR-RaLV) DNA. Leukemia Rev., 1: 310-312, 1983.
1982Yang, S. S., Taub, J., Modali, R. and Gardner, M.: Molecular cloning of the rat leukemia-helper virus DNA sequences and functional analysis of some restricted DNA fragments. Advances in Comparative Leukemia Research 1981, In: Yohn, D. S. and Blakeslee, J. R. (Eds.), Elsevier/North-Holland Biomedical Press, pp. 351-352, 1982.
1982Yang, S. S., Modali, R., Wu, R. and Gardner, M.: Molecular cloning of the endogenous rat C-type helper virus DNA sequence: Structural organization and functional analysis of some restricted DNA fragments. J. Gen. Virol., 63: 25-36, 1982.
1982Yang, S. S., Taub, J., Modali, R., Brown, D. and Murphy, E., Jr.: Biological activity of cloned rat endogenous C-type viral DNA transferred by microinjection. J. Gen. Virol., 63: 37-43, 1982.
1982Yang, S. S. and Modali, R.: Genomic complexity and molecularly cloning of a proviral DNA specific for a feral rat endogenous C-type virus, originated from a 3-methyl cholanthrene induced fibrosarcoma. Progress in Nucleic Acid Research and Molecular Biology, Vol. 29, In: Cohn, W. (Ed.), Academic Press, New York, pp. 145-149, 1982.