Target Validation in Human Tissues, 3D Models and iPSCs
Drug Discovery and Development Services
REPROCELL offers functional validation of disease targets using our human-relevant systems. Investigate the target's potential as a drug using fresh patient tissue or patient-specific iPSC-derived disease model cells.
- Ask REPROCELL to source the diseased tissue of interest
- Activate the potential target in a fresh, functional diseased tissue and measure the biological response
- Explore differences in drug response between patients and relate responses to the patient’s clinical history
- Generate customised 2D and 3D tissue models using iPSCs generated from patients with the diseased of interest
- Conduct follow-up gene expression analysis or sequencing to relate the functional activation of the target to genotype