Stem Cell Research

Stem Cell Research

Human stem cells have become widely used for both studying fundamental molecular processes of developmental biology, as well as developing new therapies for previously intractable diseases.  The manipulation of stem cells in vitro enable disease modeling and new possibilities for drug development.  Most research with human stem cells has shifted toward the use of induced pluripotent stem cells (iPSCs) for moral and ethical reasons, and regulatory restrictions.  The creation of iPSC has developed rapidly with many alternative technologies, most involving expression vectors or viral delivery.  Although effective, these technologies are increasingly problematic as the basic research shifts to translational research and clinical applications.  REPROCELL iPSC reprogramming technology is based on RNA delivery and consequently much more clinically relevant than others.

Stemgent® RNA Reprogramming Technology

mRNA provides a non-integrating, non-retained expression vehicle for gene expression, making it ideal for introducing reprogramming factors to cells. Whether you are interested in reprogramming in your lab or outsourcing reprogramming to experts, REPROCELL has the products and services to support your research. The StemRNA-NM (00-0076) and StemRNA-SR (00-0075) Reprogramming Kits provide high-efficiency, cost-effective solution for deriving iPS cells from fibroblasts, skin, or urine. When resources and time are limited, we can provide iPS cells tailored to your specific project.  See our Custom iPSC Services pages for more details.

Above: Created using the StemRNA-NM kit are iPSC colonies show above.  The cells are stained for TRA-1-60 (left), SSEA-4 (middle), NANOG (right).  

NutriStem® hPSC XF Medium

NutriStem hPSC XF Medium (01-0005) is a defined, xeno-free, serum-free, GMP-grade medium to support the growth and expansion of human iPS and ES cells. NutriStem medium provides consistent medium performance and reproducibility of human iPS and ES cells in culture. The medium is a complete formulation that maintains pluripotency and provides a stable genotype over long-terms in culture.

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Above: Human iPS (left) and ES (right) cells cultured in NutriStem hPSC XF Medium.

Other Stem Cell Reagents & Services from REPROCELL

REPROCELL has a large portfolio of catalog products to support the in vitro growth, maintenance and analysis of human iPS and stem cells.   Browse our Reagents section of the website to explore the portfolio for products that meet your needs.  From REPROCELL, you can even find iPSC-derived cell types such as neurons, cardiomyocytes and hepatocytes available in the Cells section of our web-catalog.  As a merged business organization of diverse companies, REPROCELL has products and capabilities that span a vast breadth of the stem cell and drug discovery workflow.  For your convenience, a few of our most popular products are shown below.  This REPROCELL global website provides extensive information on the entire portfolio of products and services.  We also have a brief Corporate Capabilities Guide book for your download if you would like a quick snapshot of the entire company in 8 pages.  Regardless, if you cannot find that for which you are seeking, or simply have a question, you can inquire by using the "? Make an Inquiry" link found in the sidebar or the "? Ask a Question" link on the bottom blue footer of every webpage.  We are happy to help you.

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